Precocious activation of APC/C-Cdh1 at pre-anaphase causes genome instability [PDF]
, 2008 Faithful chromosome segregation and thereby accurate gene transmission are crucial for all organisms. Until proper attachment of the mitotic spindle to the kinetochore is established, the ubiquitin ligase (E3) Cdc20-activated APC/C (anaphase promoting ...
Asuka Suzuki +6 more
core +1 more source
Signaling protein abundance modulates the strength of the spindle assembly checkpoint. [PDF]
Curr Biol, 2023 Jema S +5 more
europepmc +1 more source
Spindle assembly checkpoint and chromosome stability in Caenorhabditis elegans
, 2009 Maja Tarailo‐Graovac
openalex +1 more source
Scientific ReportsThe spindle assembly checkpoint (SAC) and spindle position checkpoint (SPOC) are essential surveillance systems that ensure accurate chromosome segregation and proper spindle orientation during mitosis.
Bashar Ibrahim
doaj +1 more source
BRCA2 Fine-Tunes the Spindle Assembly Checkpoint through Reinforcement of BubR1 Acetylation [PDF]
, 2012 Eunhee Choi +10 more
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The spindle assembly checkpoint is satisfied in the absence of interkinetochore tension during mitosis with unreplicated genomes [PDF]
, 2008 Christopher B. O’Connell +5 more
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The Spindle Assembly Checkpoint Is a Vulnerability of Aneuploid Cells [PDF]
, 2021 openalex +1 more source
PP2A-B56 opposes Mps1 phosphorylation of Knl1 and thereby promotes spindle assembly checkpoint silencing [PDF]
, 2014 Antonio Espert +5 more
openalex +1 more source
Spindle assembly checkpoint insensitivity allows meiosis-II despite chromosomal defects in aged eggs. [PDF]
EMBO Rep, 2023 Mihajlović AI +3 more
europepmc +1 more source
Functional framework of the kinetochore and spindle assembly checkpoint in Arabidopsis thaliana [PDF]
Aladár Pettkó‐Szandtner +2 more
openalex +1 more source