Results 11 to 20 of about 36,497 (260)
Editorial: Chromosome bi-orientation, tension and the spindle-assembly checkpoint. [PDF]
Front Cell Dev Biol, 2023 Schuyler SC.
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Deficient spindle assembly checkpoint in multiple myeloma.
PLoS ONE, 2011 Multiple myeloma (MM) is a hematological disease characterized by an abnormal accumulation of plasma cells in the bone marrow. These cells have frequent cytogenetic abnormalities including translocations of the immunoglobulin heavy chain gene and ...
Elena Díaz-Rodríguez +7 more
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Human kinetochores are swivel joints that mediate microtubule attachments [PDF]
eLife, 2016 Chromosome segregation is a mechanical process that requires assembly of the mitotic spindle – a dynamic microtubule-based force-generating machine.
Chris A Smith +2 more
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Kinetic framework of spindle assembly checkpoint signaling [PDF]
Nature Cell Biology, 2013 Author Posting. © The Author(s), 2013. This is the author's version of the work. It is posted here by permission of Nature Publishing Group for personal use, not for redistribution. The definitive version was published in Nature Cell Biology 15 (2013):
Dick, Amalie E., Gerlich, Daniel W.
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Evaluation of the Spindle Assembly Checkpoint Integrity in Mouse Oocytes. [PDF]
J Vis Exp, 2022 Aboelenain M, Schindler K, Blengini CS.
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Chronic deregulation of the spindle assembly checkpoint triggers myelosuppression and gastrointestinal atrophy [PDF]
, 2023 Karbon G +11 more
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Spindle assembly checkpoint and its regulators in meiosis [PDF]
Human Reproduction Update, 2011 BACKGROUND Meiosis is a unique form of cell division in which cells divide twice but DNA is duplicated only once. Errors in chromosome segregation during meiosis will result in aneuploidy, followed by loss of the conceptus during pregnancy or birth defects. During mitosis, cells utilize a mechanism called the spindle assembly checkpoint (SAC) to ensure
Shao‐Chen Sun, Nam‐Hyung Kim
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The spindle assembly checkpoint [PDF]
Current Biology, 2008 (Current Biology 18, R391–R395; July 22, 2008)Because of an editorial mistake, Figure 1Figure 1 of this Primer shows pairs of kinetochores (indicated by pairs of yellow dots) during telophase, instead of single kinetochores as indicated in the corrected figure that appears here. The journal regrets this error.Figure 1The SAC as a synchronization device(
Varetti, Gianluca, Musacchio, Andrea
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PICH impacts the spindle assembly checkpoint via its DNA translocase and SUMO-interaction activities. [PDF]
Life Sci AllianceLama B +11 more
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Scientific Reports, 2021 Phosphatidylinositol glycan anchor biosynthesis class N (PIGN) has been linked to the suppression of chromosomal instability. The spindle assembly checkpoint complex is responsible for proper chromosome segregation during mitosis to prevent chromosomal ...
Emmanuel K. Teye +9 more
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