Green Synthesis and Catalysis, 2021 An uncommon aza-Diels-Alder reaction of electron-deficient azoalkenes and electron-deficient 3-phenacylideneoxindoles was successfully developed for convenient construction of the heterocyclic spirooxindoles.
Wenjing Shi, Jing Sun, Chao-Guo Yan
doaj
Efficient synthesis of spirooxindole-pyrrolizidines and dispirooxindole-piperazines
Synthetic Communications, 2018 A simple and efficient approach for the construction of spirooxindole-pyrrolizidines and dispirooxindole-piperazines by cycloaddition reaction of azomethine ylide generated by isatin and proline has been demonstrated successfully. The formation of two different types of frameworks by two different modes of cycloaddition is explored.
Keshri Nath Tiwari +3 more
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Porous CuO catalysed green synthesis of some novel 3-alkylated indoles as potent antitubercular agents [PDF]
A green multicomponent one pot synthesis of novel 2-(1H-indol-3-ylmethyl)-5,5-dimethyl-cyclohexane-1,3-diones (4a–l) in excellent yields was conveniently carried out in aqueous medium at room temperature over mpCuO as heterogeneous catalyst.
Das, Ratnesh +4 more
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Journal of Enzyme Inhibition and Medicinal Chemistry, 2020 In the current medical era, spirooxindole motif stands out as a privileged heterospirocyclic scaffold that represents the core for a wide range of bioactive naturally isolated products (such as Strychnofoline and spirotryprostatins A and B) and synthetic
Sara T. Al-Rashood +7 more
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RSC Advances, 2015 The development of a versatile new one pot, catalyst free, multicomponent-tandem strategy for assembly of spirooxindole-indazolones and spirooxindole-pyrazolines is described.
Jagdamba Singh +4 more
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Morphological Profiling Identifies the Motor Protein Eg5 as Cellular Target of Spirooxindoles [PDF]
, 2023 Jie Liu +13 more
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Design, synthesis, and antitumor activity of novel dispiro[oxindole-cyclohexanone]-pyrrolidines [PDF]
, 2022 Azab, Mohamed +7 more
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Expanding the chemical diversity of spirooxindoles via alkylative pyridine dearomatization
Beilstein Journal of Organic Chemistry, 2012 A mild and practical synthesis of spirooxindole [1,3]oxazino derivatives from N-substituted isatins and 1,3-dicarbonyl compounds with pyridine derivatives is reported. The reactions provided good to excellent yields.
Chunhui Dai +2 more
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A novel alpha‐amylase inhibitor‐based
, 2023 Mohammad Shahidul Islam +9 more
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Green Synthesis of Spirooxindoles via Lipase-Catalyzed One-Pot Tandem Reaction in Aqueous Media [PDF]
, 2023 Yong Tang +7 more
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