Results 131 to 140 of about 3,124 (225)

Stereoselective synthesis of CF₃-containing spirocyclic-oxindoles using N-2,2,2-trifluoroethylisatin ketimines: an update. [PDF]

RSC Adv, 2023
Borah B, Veeranagaiah NS, Sharma S, Patat M, Prasad MS, Pallepogu R, Chowhan LR.   +6 more
europepmc   +1 more source

Spirooxindole Derivative SOID-8 Induces Apoptosis Associated with Inhibition of JAK2/STAT3 Signaling in Melanoma Cells

, 2012
Yan Tian, Sangkil Nam, Lucy Liu, Fumiko Yakushijin, Kenichi Yakushijin, Ralf Buettner, Wei Liang, Fan Yang, Yuelong Ma, David Horne, Richard Jove   +10 more
openalex   +2 more sources

Spirooxindoles derivatives as novel inhibitors of the respiratory syncytial virus [PDF]

, 2017
Respiratory Syncytial Virus (RSV) is an important pathogen that affects the lower respiratory track resulting in hospitalisation in infants and young children and is a significant cause of morbidity and mortality in the elderly and immunocompromised ...
Paradowski, Michael
core  

Rational drug design, synthesis, and biological evaluation of novel chiral tetrahydronaphthalene-fused spirooxindole as MDM2-CDK4 dual inhibitor against glioblastoma

Acta Pharmaceutica Sinica B, 2020
Simultaneous inhibition of MDM2 and CDK4 may be an effective treatment against glioblastoma. A collection of chiral spirocyclic tetrahydronaphthalene (THN)-oxindole hybrids for this purpose have been developed.
Biao Wang, Fu Peng, Wei Huang, Jin Zhou, Nan Zhang, Jia Sheng, Phensinee Haruehanroengra, Gu He, Bo Han   +8 more
doaj  

H3PW12O40: An Efficient Catalyst for the Synthesis of Spirooxindoles Under Ultrasound Irradiation

, 2013
Marjaneh Samadizadeh
openalex   +1 more source

Synthesis of Spirooxindoles Using CuFe2O4 Nanoparticles [PDF]

Synfacts, 2013
Makoto Nagaosa, Yasuhiro Uozumi
openaire   +2 more sources

Titanium(IV)-Catalyzed Stereoselective Synthesis of Spirooxindole-1-pyrrolines

, 2014
Joseph J. Badillo, Carlos J. A. Ribeiro, Marilyn M. Olmstead, Annaliese K. Franz   +3 more
openalex   +1 more source

Editorial: Biosynthesis and regulation of plant specialized metabolisms. [PDF]

Front Plant Sci, 2023
Zhang W, Xu F, Kwon M.
europepmc   +1 more source

Combined Scaffold Evaluation and Systems‐Level Transcriptome‐Based Analysis for Accelerated Lead Optimization Reveals Ribosomal Targeting Spirooxindole Cyclopropanes

, 2019
Kevin X. Rodriguez, Erin N. Howe, Emily P. Bacher, Miranda Burnette, Jennifer L. Meloche, Jayda E. Meisel, Patricia M. Schnepp, Xuejuan Tan, Mayland Chang, Jeremiah J. Zartman, Siyuan Zhang, Brandon L. Ashfeld   +11 more
openalex   +2 more sources

Quantitative structure-activity relationship and ADME prediction studies on series of spirooxindoles derivatives for anti-cancer activity against colon cancer cell line HCT-116

Heliyon
Forty-one derivatives of spirooxindoles, active against HCT-116 colon cancer cells, underwent pharmacophore-based 3D-QSAR analysis to understand their correlation with anti-cancer activity. The study identified a seven-point pharmacophore model (ADHHRRR1)
Sukhmeet Kaur, Jasneet Kaur, Bilal Ahmad Zarger, Nasarul Islam, Nazirah Mir   +4 more
doaj