Results 31 to 40 of about 11,943 (150)
Regulation of squalene epoxidase in HepG2 cells.
Journal of Lipid Research, 1990 Regulation of squalene epoxidase in the cholesterol biosynthetic pathway was studied in a human hepatoma cell line, HepG2 cells. Since the squalene epoxidase activity in cell homogenates was found to be stimulated by the addition of Triton X-100, enzyme ...
Y Hidaka, T Satoh, T Kamei
doaj +1 more source
The use and mechanism of action of terbinafine compared to other antifungal drugs used in the pharmacotherapy of candidiasis [PDF]
Farmacja Polska, 2021 Terbinafine as an antifungal drug was introduced to the world market in 1991, which was a great advance in dermatology. From that time to 1999, it was used orally with good results in over 10 million people and locally in over 30 million.
Piotr Mariusz Dwiecki +2 more
doaj +1 more source
Journal of Lipid Research, 1987 Squalene epoxidase activity has been studied in cell-free preparations of Chinese hamster ovary (CHO) cells and rat liver. In contrast to rat liver microsomal squalene epoxidase, the enzyme of CHO cells is only slightly activated by the autologous ...
H Eilenberg, I Shechter
doaj +1 more source
Emerging Infectious Diseases, 2022 We describe 7 cases of extensive tinea corporis since 2018 in a hospital in Paris, France, after failure to cure with terbinafine. Molecular analysis indicated Trichophyton mentagrophytes internal transcribed spacer type VIII (T. indotineae).
Sarah Dellière +10 more
doaj +1 more source
Journal of Lipid Research, 1989 The activity of rat liver microsomal squalene epoxidase is inhibited effectively by digitonin. Concentrations of 0.8 to 1.2 mg/ml of digitonin cause total inhibition of microsomal (0.75 mg protein/ml) squalene epoxidase either in microsomes that were ...
H Eilenberg +3 more
doaj +1 more source
Purification and characterization of recombinant squalene epoxidase
Journal of Lipid Research, 1995 Recombinant rat squalene epoxidase (rSE) was expressed in E. coli and purified to an apparent homogeneity. This expression system was constructed using squalene epoxidase (SE) cDNA in which nucleotides coding 99 amino acids in the N-terminal were deleted
A Nagumo, T Kamei, J Sakakibara, T Ono
doaj +1 more source
Stimulation by unsaturated fatty acid of squalene uptake in rat liver microsomes.
Journal of Lipid Research, 1985 Supernatant protein factor (SPF) and anionic phospholipids such as phosphatidylglycerol (PG) stimulate squalene epoxidase activity in rat liver microsomes by promoting [3H]squalene uptake as well as substrate translocation (Chin, J., and K. Bloch.
J Chin, K Bloch
doaj +1 more source
Green Microalgae Strain Improvement for the Production of Sterols and Squalene
Plants, 2021 Sterols and squalene are essential biomolecules required for the homeostasis of eukaryotic membrane permeability and fluidity. Both compounds have beneficial effects on human health. As the current sources of sterols and squalene are plant and shark oils,
Supakorn Potijun +4 more
doaj +1 more source
Journal of Fungi, 2021 Numerous reports describe the emergence of resistance in dermatophytes, especially in T. rubrum and T. mentagrophytes/indotineae strains. We here present a review of the current status of resistance in dermatophytes worldwide.
Rosalie Sacheli, Marie-Pierre Hayette
doaj +1 more source
, 2022 supplementary materials for article 'A prospective cross-sectional study of squalene epoxidase mutations in U.S. onychomycosis patients: implications for management – our troubles are just beginning'
Wang, T (via Mendeley Data), Wang, Tong
core +2 more sources