Results 51 to 60 of about 16,641 (185)
Journal of Fungi, 2021 Numerous reports describe the emergence of resistance in dermatophytes, especially in T. rubrum and T. mentagrophytes/indotineae strains. We here present a review of the current status of resistance in dermatophytes worldwide.
Rosalie Sacheli, Marie-Pierre Hayette
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Effect of detergents on sterol synthesis in a cell-free system of yeast
Journal of Lipid Research, 1982 In order to obtain information about the reactivity of enzymes in sterol synthesis of yeast, the effects of some detergents were investigated. Among the detergents used, Triton X-100 was found to exert a unique action, and its effect on the incorporation
S Hata, T Nishino, N Ariga, H Katsuki
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Cholesterol mediated ferroptosis suppression reveals essential roles of Coenzyme Q and squalene
Communications Biology, 2023 Recent findings have shown that fatty acid metabolism is profoundly involved in ferroptosis. However, the role of cholesterol in this process remains incompletely understood.
Qi Sun +11 more
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Intermembrane transfer of squalene promoted by supernatant protein factor
Journal of Lipid Research, 1983 Supernatant protein factor (SPF), a protein that stimulates squalene epoxidation, mediates the transfer of squalene between two separable microsomal populations (Kojima, Y., E. J. Friedlander, and K. Bloch, 1981. J. Biol Chem. 256: 7235-7239).
D Fuks-Holmberg, K Bloch
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Journal of Lipid Research, 1997 The relationship between the inhibition of cholesterol biosynthesis and occurrence of myopathy was studied in L6 myoblasts using two lines of cholesterol biosynthesis inhibitors, 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase inhibitor ...
S Matzno +8 more
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Improving the co-production of triacylglycerol and isoprenoids in Chlamydomonas [PDF]
Biofuel Research Journal, 2020 Biodiesel and natural products derived from microalgae require a smaller land area and have higher production rates compared to plants and animals and has recently attracted considerable interest.
Supakorn Potijun +4 more
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Journal of Lipid Research, 1996 Exposure of weanling rats to a diet containing the element tellurium results in specific inhibition of squalene epoxidase, an obligate enzyme in cholesterol biosynthesis.
A D Toews +4 more
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Mycoses (Berlin), 2023 Numerous reports of resistance to terbinafine in Trichophyton spp. from all over the world are arousing justified attention and concern. Point mutations in the gene that encodes the squalene epoxidase (SQLE) enzyme are responsible for these therapeutic ...
P. Bortoluzzi +11 more
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Squalene epoxidase as a target for manipulation of squalene levels in the yeastSaccharomyces cerevisiae [PDF]
FEMS Yeast Research, 2013 Squalene is a valuable natural substance with several biotechnological applications. In the yeast Saccharomyces cerevisiae, it is produced in the isoprenoid pathway as the first precursor dedicated to ergosterol biosynthesis. The aim of this study was to explore the potential of squalene epoxidase encoded by the ERG1 gene as the target for manipulating
Martina, Garaiová +4 more
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1% film-forming terbinafine solution in therapy in patients with long-lasting foot mycoses
Медицинский совет, 2019 Topical antimycotic agents are used in the treatment of foot mycosis. Numerous studies have shown the efficacy of terbinafine. Fungistatic activity of the medication is provided by blockade of action of squalene epoxidase enzyme and subsequent inhibition
I. V. Hamaganova, A. A. Tsykin
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