Results 51 to 60 of about 14,256 (222)

Synthetic strategies toward 1,3-oxathiolane nucleoside analogues

open access: yesBeilstein Journal of Organic Chemistry, 2021
Sugar-modified nucleosides have gained considerable attention in the scientific community, either for use as molecular probes or as therapeutic agents. When the methylene group of the ribose ring is replaced with a sulfur atom at the 3’-position, these ...
Umesh P. Aher   +3 more
doaj   +1 more source

Synthetic explorations of the briarane jungle: progress in developing a synthetic route to a common family of diterpenoid natural products [PDF]

open access: yesRoyal Society Open Science, 2018
The briarane diterpenoids are a large family of marine natural products that have been primarily isolated from gorgonian octocorals around the world.
Nicholas G. Moon, Andrew M. Harned
doaj   +1 more source

Understand the Specific Regio- and Enantioselectivity of Fluostatin Conjugation in the Post-Biosynthesis

open access: yesBiomolecules, 2020
Fluostatins, benzofluorene-containing aromatic polyketides in the atypical angucycline family, conjugate into dimeric and even trimeric compounds in the post-biosynthesis.
Yuanqi Wang   +4 more
doaj   +1 more source

Synthetic avenues towards a tetrasaccharide related to Streptococcus pneumonia of serotype 6A

open access: yesBeilstein Journal of Organic Chemistry, 2018
Streptococcus pneumonia (SPn) is a Gram-positive bacterium which causes life threatening diseases. The bacteria protect themselves against non-specific host defence by an external polysaccharide (PS) capsule which bears a repeating unit, α-D-Galp(1->3)-α-
Aritra Chaudhury   +2 more
doaj   +1 more source

Stereoselective synthesis of tetrasubstituted alkenes via a sequential carbocupration and a new sulfur–lithium exchange

open access: yesBeilstein Journal of Organic Chemistry, 2012
We have designed a new sequential carbocupration and sulfur–lithium exchange that leads stereo- and regioselectively to trisubstituted alkenyllithiums.
Andreas Unsinn, Cora Dunst, Paul Knochel
doaj   +1 more source

stereoselectivity

open access: yes, 2014
Citation: 'stereoselectivity' in the IUPAC Compendium of Chemical Terminology, 3rd ed.; International Union of Pure and Applied Chemistry; 2006. Online version 3.0.1, 2019. 10.1351/goldbook.S05991 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire   +1 more source

N-Heterocyclic carbene/Brønsted acid cooperative catalysis as a powerful tool in organic synthesis

open access: yesBeilstein Journal of Organic Chemistry, 2012
The interplay between metals and N-heterocyclic carbenes (NHCs) has provided a window of opportunities for the development of novel catalytic strategies within the past few years.
Rob De Vreese, Matthias D’hooghe
doaj   +1 more source

Influência da estrutura do catalisador a base de Zirconoceno na estereorregularidade e propriedades do polipropileno formado Influence of Zirconocene structure on polypropylene stereorregularity and properties

open access: yesPolímeros, 1997
RESUMO: Catalisadores de metalocenos com diferentes simetrias, cocatalisados por metilaluminoxanas (MAO), foram avaliados em diferentes temperaturas de polimerização do propileno.
Mário R. Meneghetti   +2 more
doaj   +1 more source

Synthesis of Chiral Acyclic Pyrimidine Nucleoside Analogues from DHAP-Dependent Aldolases

open access: yesBiomolecules
Dihydroxyacetone phosphate (DHAP)-dependent aldolases catalyze the aldol addition of DHAP to a variety of aldehydes and generate compounds with two stereocenters.
Mariano Nigro   +7 more
doaj   +1 more source

Genome‐Guided Discovery of Antimalarial 4‐Amino‐2,4‐Pentadienoate‐Containing Cyclolipodepsipeptides

open access: yesAngewandte Chemie International Edition, EarlyView.
Halogenated and glycosylated 4‐amino‐2,4‐pentadienoate‐containing cyclolipodepsipeptides (APD‐CLDs) exhibit potent antiplasmodial activity (IC50 = 25–161 nM) against drug‐sensitive and resistant Plasmodium falciparum strains. ABSTRACT 4‐Amino‐2,4‐pentadienoate‐containing cyclolipodepsipeptides (APD‐CLDs) represent a structurally distinctive family of ...
Hartono Candra   +10 more
wiley   +1 more source

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