Results 191 to 200 of about 12,900 (288)

Store-Operated Ca²⁺ Entry in Skeletal Muscle Contributes to the Increase in Body Temperature during Exertional Stress. [PDF]

Int J Mol Sci, 2022
Girolami B, Serano M, Michelucci A, Pietrangelo L, Protasi F.   +4 more
europepmc   +1 more source

ATL2 Recruits TRAK1 to Promote Mitochondrial Transport at ER–Mitochondria Contact Sites

Advanced Science, EarlyView.
ABSTRACT Mitochondrial transport and distribution are crucial for cellular homeostasis, yet whether and how they are regulated by endoplasmic reticulum (ER)–mitochondria contact sites remains unclear. Here, we demonstrate that the ER protein atlastin‐2 (ATL2) orchestrates mitochondrial transport and distribution by promoting assembly of the transport ...
Yiru Cheng, Peiyuan Chai, Xiayuhe Pei, Yiwen Chen, Xiaoshuai Huang, Bei Liu, Yiqian Wu, Junlin Teng, Pengli Zheng, Jianguo Chen   +9 more
wiley   +1 more source

Defining the interactome of the pancreas-specific SPCA2 isoform (SPCA2C) identifies unique links to store-operated Ca²⁺ entry. [PDF]

FEBS J
Samardzija P, Fenech MA, Hassan O, Lang R, Carter MC, Chen S, Shi S, Ramachandran R, Stathopulos PB, Pin CL.   +9 more
europepmc   +1 more source

Orai2 Modulates Store-Operated Ca²⁺ Entry and Cell Cycle Progression in Breast Cancer Cells. [PDF]

Cancers (Basel), 2021
Sanchez-Collado J, Lopez JJ, Cantonero C, Jardin I, Regodón S, Redondo PC, Gordillo J, Smani T, Salido GM, Rosado JA.   +9 more
europepmc   +1 more source

Scalable Crackle‐Lithography for Multifunctional Enclosed Plastic Nanofluidic Devices

Advanced Science, EarlyView.
Crackle‐lithography enables scalable fabrication of enclosed plastic‐substrate‐based nanofluidic devices with interconnected nanochannels that enable molecular transport, optical interrogation, confined electroless copper deposition, and ionic memristive behavior.
Tirumala Rao Dumpala, S. Kiruthika, Siddhi Vinayak Pandey, Junyang Zhang, Solleti Goutham, Marcos Vinicius Surmani Martins, Harry Whittingham, Boya Radha, Ashok Keerthi   +8 more
wiley   +1 more source

Store-operated Ca²⁺ entry is involved in endothelium-to-mesenchymal transition in lung vascular endothelial cells. [PDF]

Am J Physiol Lung Cell Mol Physiol
Babicheva A, Elmadbouh I, Song S, Thompson MA, Powers R, Jain PP, Izadi A, Chen J, Yung L, Parmisano S, Paquin C, Wang WT, Chen Y, Wang T, Alotaibi M, Shyy JY, Thistlethwaite PA, Wang J, Makino A, Prakash YS, Pabelick CM, Yuan JX.   +21 more
europepmc   +1 more source

The interplay between mitochondria and store-operated Ca²⁺ entry: Emerging insights into cardiac diseases. [PDF]

J Cell Mol Med, 2021
Nan J, Li J, Lin Y, Saif Ur Rahman M, Li Z, Zhu L.   +5 more
europepmc   +1 more source

A Rare De Novo Missense Mutation in IFT122 Confers a Genetic Susceptibility Factor of Idiopathic Pediatric Uveitis Via Trio‐based Whole‐Exome Sequencing

Advanced Science, EarlyView.
A rare de novo IFT122‐A773E variant is identified in idiopathic pediatric uveitis and shown to exacerbate retinal inflammation and barrier dysfunction. Mechanistically, the variant enhances IFT43 interaction, elevates calcium signaling, and activates the MEK/ERK/FRA1 axis, revealing a previously unrecognized cilia‐associated pathway that may increase ...
Qian Zhou, Jiaxing Huang, Yilin Wang, Xingran Li, Xianyang Liu, Lingyu Dai, Hongshun Li, Qingfeng Wang, Jiangyi Liu, Guannan Su, Wanyun Zhang, Yang Deng, Qingfeng Cao, Yujie Lai, Xiang Luo, Changwei Huang, Ling Chen, Shengping Hou, Peizeng Yang   +18 more
wiley   +1 more source

Side-by-side comparison of published small molecule inhibitors against thapsigargin-induced store-operated Ca2+ entry in HEK293 cells. [PDF]

PLoS One
Norman K, Hemmings KE, Shawer H, Appleby HL, Burnett AJ, Hamzah N, Gosain R, Woodhouse EM, Beech DJ, Foster R, Bailey MA.   +10 more
europepmc   +1 more source

Role of Store-Operated Ca²⁺ Entry in the Pulmonary Vascular Remodeling Occurring in Pulmonary Arterial Hypertension. [PDF]

Biomolecules, 2021
Masson B, Montani D, Humbert M, Capuano V, Antigny F.   +4 more
europepmc   +1 more source