Results 31 to 40 of about 32,791,583 (267)

TGF beta 1 attenuates expression of prolactin and IGFBP-1 in decidualized endometrial stromal cells by both SMAD-dependent and SMAD-independent pathways [PDF]

open access: yes, 2010
Background: Decidualization (differentiation) of the endometrial stromal cells during the secretory phase of the menstrual cycle is essential for successful implantation.
Jones Marius   +30 more
core   +1 more source

Control of PD-L1 expression in CLL-cells by stromal triggering of the Notch-c-Myc-EZH2 oncogenic signaling axis

open access: yesJournal for ImmunoTherapy of Cancer, 2021
Chronic lymphocytic leukemia (CLL) is the most common leukemia in adults. Emerging data suggest that CLL-cells efficiently evade immunosurveillance. T-cell deficiencies in CLL include immuno(metabolic) exhaustion that is achieved by inhibitory molecules,
Paolo Ghia   +9 more
doaj   +1 more source

Relative contributions of stromal interaction molecule 1 and CalDAG-GEFI to calcium-dependent platelet activation and thrombosis: STIM1 and CalDAG-GEFI in platelet activation [PDF]

open access: yes, 2011
Stromal interaction molecule 1 (STIM1) was recently identified as a critical component of store-operated calcium entry (SOCE) in platelets. We previously reported the Ca2+-sensing guanine nucleotide exchange factor CalDAG-GEFI as critical molecule in Ca2+
OUELLETTE, T. D.   +6 more
core   +1 more source

Novel fluorescent reporters for the Stromal Interaction Molecule 1

open access: yesThe FASEB Journal, 2013
The stromal interaction molecule 1 (Stim1) is a Ca 2+ sensor in the endoplasmic/sarcoplasmic reticulum whose Ca 2+ sensing triggers its dimerization and subsequent activation of store‐operated Ca 2+ entry via ...
Mark VerMeer, KIM TRAN
openaire   +1 more source

Characterization of lymph node stromal cells during Treg-mediated tolerance [PDF]

open access: yes, 2013
Solid organs transplantation is therapy of choice for several human diseases. The success of this treatment is determined by the recipientÕs ability to prevent rejection.
Broggi, Maria Anna Sofia
core   +1 more source

Control of human endometrial stromal cell motility by PDGF-BB, HB-EGF and trophoblast-secreted factors [PDF]

open access: yes, 2013
Human implantation involves extensive tissue remodeling at the fetal-maternal interface. It is becoming increasingly evident that not only trophoblast, but also decidualizing endometrial stromal cells are inherently motile and invasive, and likely ...
Annemarie Samalecos   +39 more
core   +1 more source

Effects of subchronic fluoride exposure through drinking water on renal toxicity and the expressions of STIM1 and ORAI1 in renal tissues in mice

open access: yes环境与职业医学, 2022
BackgroundIt has been found that fluoride may cause cell damage by inducing intracellular calcium overload. Store-operated calcium entry (SOCE) plays an important role in maintaining intracellular calcium homeostasis, but the effect of fluoride on renal ...
Xuan WU, Fan DING, Yingying LIU, Qing WU
doaj   +1 more source

Mesenchymal Differentiation and Organ Distribution of Established Human Stromal Cell Lines in NOD/SCID Mice [PDF]

open access: yes, 2001
Two human stromal cell lines were established previously from bone marrow-derived primary long-term cultures by immortalization using the SV40 large T antigen and cellular cloning. After irradiation, the fibroblast-like cell lines L87/4 and L88/5 support
Thalmeier, Karin   +6 more
core   +1 more source

Melanoma-associated adhesion molecule MUC18/MCAM (CD146) and transcriptional regulator Mader in normal human CNS [PDF]

open access: yes, 1998
The proteins MUC18 and Mader have been identified as markers of tumor progression in melanoma cells, MUC18, also known as MCAM (melanoma cell adhesion molecule) and as CD146 (endothelial antigen), is a cell adhesion molecule belonging to the ...
Müller, Norbert   +7 more
core   +1 more source

Single molecule force spectroscopy on ligand-DNA complexes: from molecular binding mechanisms to biosensor applications [PDF]

open access: yes, 2004
Ros R, Eckel R, Bartels FW, et al. Single molecule force spectroscopy on ligand-DNA complexes: from molecular binding mechanisms to biosensor applications. Journal of Biotechnology.
Baumgarth, Birgit   +9 more
core   +1 more source

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