Results 61 to 70 of about 1,937 (151)

Perception and processing of stress signals by plant mitochondria

The Plant Journal, Volume 120, Issue 6, Page 2337-2355, December 2024.
Significance Statement Besides their role in energy metabolism, plant mitochondria have emerged as highly dynamic signalling hubs that integrate external stimuli to coordinate numerous cellular processes including responses to environmental stress. In this review, we provide an overview of the current knowledge on perception and processing of stress ...
Jennifer Selinski, Stephanie Frings, Romy Schmidt‐Schippers   +2 more
wiley   +1 more source

QTL Mapping of Melampsora Leaf Rust Resistance and Yield Component Traits in the Salix F1 Hybrid Common Parent Population

GCB Bioenergy, Volume 16, Issue 10, October 2024.
Pedigrees of the Salix F1 hybrid common parent (HCP) mapping populations. The Salix F1 HCP was comprised of two half‐sib families, both with a S. purpurea common parent and each consisting of four F1 families. Reciprocal crosses were made with male and female S. viminalis and S. suchowensis while S. integra, S. udensis, and S.
Dustin G. Wilkerson, Chase R. Crowell, Christine D. Smart, Lawrence B. Smart   +3 more
wiley   +1 more source

Nrf2 as a regulator of energy metabolism and mitochondrial function

FEBS Letters, Volume 598, Issue 17, Page 2092-2105, September 2024.
Nrf2 activates the expression of many genes involved in intermediary metabolic pathways such as glycolysis, the pentose phosphate pathway, fatty acid oxidation, and glutaminolysis. Nrf2 also modulates substrate utilization for mitochondrial respiration.
Alina Luchkova, Ana Mata, Susana Cadenas
wiley   +1 more source

Sulfiredoxin is Regulated by NRF2 During Oxidative Stress in Lungs

The FASEB Journal, 2008
Mammalian sulfiredoxin (SRX) plays a role in the regulation of oxidative stress. However, the transcriptional regulation of SRX in response to oxidative stress is not clear. Here we demonstrated that NRF2 transcription factor regulates SRX expression following oxidative stress in lungs. In response to cigarette smoke exposure, lungs from wild‐type mice
Guoyu Ling, Thomas E Sussan, Rajesh K Thimmulappa, Shyam Biswal   +3 more
openaire   +1 more source

Dissecting the integrative antioxidant and redox systems in plant mitochondria. Effect of stress and S-nitrosylation.

Frontiers in Plant Science, 2013
Mitochondrial respiration provides the energy needed to drive metabolic and transport processes in cells. Mitochondria are a significant site of reactive oxygen species (ROS) production in plant cells, and redox-system components obey fine regulation ...
Juan José Lázaro, Ana eJiménez, Daymi eCamejo, Iván eiglesias-Baena, María Carmen Martí, Alfonso eLázaro-Payo, Sergio eBarranco-Medina, Francisca eSevilla   +7 more
doaj   +1 more source

Diabetic neuropathy: A NRF2 disease?

Journal of Diabetes, Volume 16, Issue 9, September 2024.
Highlights Nuclear factor erythroid 2‐related factor 2 (NRF2) is an oxidant stress response transcription factor, and is involved in metabolism, inflammation, autophagy, proteostasis, mitochondrial physiology, and immune responses. Chronic hyperglycemia in diabetes and prediabetes conditions induces a decrease in NRF2 that leads to an increase of ...
Monica Neagu, Carolina Constantin, Mihaela Surcel, Adriana Munteanu, Cristian Scheau, Ilinca Savulescu‐Fiedler, Constantin Caruntu   +6 more
wiley   +1 more source

The Dual-Targeted Plant Sulfiredoxin Retroreduces the Sulfinic Form of Atypical Mitochondrial Peroxiredoxin   [PDF]

Plant Physiology, 2010
Abstract Sulfiredoxin (Srx) couples the energy of ATP hydrolysis to the energetically unfavorable process of reducing the inactive sulfinic form of 2-cysteine peroxiredoxins (Prxs) to regenerate its active form. In plants, Srx as well as typical 2-cysteine Prx have been considered as enzymes with exclusive chloroplast localization.
Iván, Iglesias-Baena, Sergio, Barranco-Medina, Francisca, Sevilla, Juan-José, Lázaro   +3 more
openaire   +2 more sources

Hydroxymethylglutaryl‐CoA reductase activity is essential for mitochondrial β‐oxidation of fatty acids to prevent lethal accumulation of long‐chain acylcarnitines in the mouse liver

British Journal of Pharmacology, Volume 181, Issue 16, Page 2750-2773, August 2024.
Abstract Background and Purpose Statins are competitive inhibitors of 3‐hydroxy‐3‐methylglutaryl coenzyme A (HMG‐CoA) reductase (HMGCR), and exert adverse effects on mitochondrial function, although the mechanisms underlying these effects remain unclear.
Edgars Liepinsh, Liga Zvejniece, Laura Clemensson, Melita Ozola, Edijs Vavers, Helena Cirule, Stanislava Korzh, Sandra Skuja, Valerija Groma, Monta Briviba, Solveiga Grinberga, Wen Liu, Paweł Olszewski, Mélissa Gentreau, Robert Fredriksson, Maija Dambrova, Helgi B. Schiöth   +16 more
wiley   +1 more source

CRL3Keap1 E3 ligase facilitates ubiquitin-mediated degradation of oncogenic SRX to suppress colorectal cancer progression

Nature Communications
The antioxidant protein sulfiredoxin-1 (SRX) is an oncogenic factor that promotes tumor progression, but the regulatory mechanism underlying SRX degradation remains to be understood.
Feng Zhu, Liangshan Li, Yuanyuan Chen, Yongfu Pan, Wenjuan Zhang, Lihui Li, Lili Cai, Xiaoxue Zhao, Hu Zhao, Shiwen Wang, Lijun Jia   +10 more
doaj   +1 more source

Association of Salivary Levels of Heme Oxygenase-1 and Sulfiredoxin-1 with Periodontal Health in Smokers and Nonsmokers: A Cross-Sectional Analytical Study

Dental Hypotheses
Introduction: We aimed to determine the association between salivary levels of heme oxygenase 1 (HO-1) and sulfiredoxin-1 (SRXN-1) with periodontal health in smokers and nonsmokers.
Tamara A. Mohammmed, Omar Husham Ali
doaj   +1 more source