Results 91 to 100 of about 44,470 (243)
Tubulin gene expression during synaptogenesis in rat, mouse and chick brain
, 1991 Studies on tubulin gene expression in brains from three different species, viz rat, mouse and chick, varying with respect to their periods of synaptogenesis, show that the rise and fall in the level of tubulin during synaptogenesis is closely parallel to
P.K. Sarkar +3 more
core +1 more source
Agrin isoforms and their role in synaptogenesis [PDF]
, 1992 Agrin is thought to mediate the motor neuron-induced aggregation of synaptic proteins on the surface of muscle fibers at neuromuscular junctions. Recent experiments provide direct evidence in support of this hypothesis, reveal the nature of agrin ...
McMahan, U. J. +12 more
core +1 more source
Cannabinoid exposure during pregnancy: Cardiorespiratory effects and offspring outcomes
The Journal of Physiology, EarlyView.Abstract figure legend Prenatal exposure to cannabinoids has been investigated across human and animal studies to understand its impact on physiological development. Evidence suggests that early‐life cannabinoid exposure influence multiple developmental processes, extending beyond neurodevelopmental outcomes to potentially affect placental function ...
Luis Gustavo A. Patrone +1 more
wiley +1 more source
Cerebellar synaptogenesis is compromised in mouse models of DYT1 dystonia
, 2015 Early-onset torsion dystonia (DYT1) is an autosomal-dominant movement disorder characterized by sustained muscle contractions and abnormal posturing. It is caused by a three base-pair deletion (ΔGAG) in the gene encoding the AAA(+) protein torsinA, which
Mandolesi G +6 more
core +2 more sources
New insights into Reelin-mediated signaling pathways
Frontiers in Cellular Neuroscience, 2016 Reelin, a multifunctional extracellular protein that is important for mammalian brain development and function, is secreted by different cell types in the prenatal or postnatal brain.
Gum Hwa eLee, Gabriella eD'Arcangelo
doaj +1 more source
Astrocytes promote peripheral nerve injury-induced reactive synaptogenesis in the neonatal CNS
, 2011 Neonatal damage to the trigeminal nerve leads to “reactive synaptogenesis” in the brain stem sensory trigeminal nuclei. In vitro models of brain injury-induced synaptogenesis have implicated an important role for astrocytes.
Fu-Sun Lo +2 more
core +1 more source
Identification of Small Molecules that Enhance Synaptogenesis Using Synapse Microarrays [PDF]
, 2013 Synaptic function is affected in many brain diseases and disorders. Technologies for large-scale synapse assays can facilitate identification of drug leads.
Shi, Peng +7 more
core +1 more source
Psychotropic medication and the fetal brain
The Journal of Physiology, EarlyView.Abstract figure legend Brain region changes linked to in‐utero psychotropic exposure. Abstract Medications known to cross the blood–brain barrier (psychotropic medications) are commonly prescribed to women during pregnancy, often for the management of mental illness.
Oliver Gale‐Grant, Tomoki Arichi
wiley +1 more source
Neuromuscular synaptogenesis in wild type and mutant zebrafish
, 2006 The specificity of synaptic connections that is essential for nervous system function arises during development through a series of events, including axon outgrowth, pathway selection, target selection, and synaptogenesis.
Panzer, Jessica A
core
The Journal of Physiology, EarlyView.Abstract figure legend Suboptimal maternal nutrition alters placental and developing blood–brain barrier (BBB) protective function and is associated with increased fetal brain vulnerability. In the placenta, nutritional adversity may reduce the exchange surface area and promote meta‐inflammation, compromising barrier efficiency in a model‐ and context ...
Kristin L. Connor +4 more
wiley +1 more source