Results 51 to 60 of about 44,470 (243)

Antioxidant and Anti-Inflammatory Effects of Garlic in Ischemic Stroke: Proposal of a New Mechanism of Protection through Regulation of Neuroplasticity

Antioxidants, 2023
Stroke represents one of the main causes of death and disability in the world; despite this, pharmacological therapies against stroke remain insufficient. Ischemic stroke is the leading etiology of stroke.
Sandra Monserrat Bautista-Perez, Carlos Alfredo Silva-Islas, Oscar Uriel Sandoval-Marquez, Jesús Toledo-Toledo, José Manuel Bello-Martínez, Diana Barrera-Oviedo, Perla D. Maldonado   +6 more
doaj   +1 more source

Synaptogenesis in the Developing Rat Cerebellum [PDF]

, 2017
cerebellum, development, synaptogenesis, synaptophysin.The aim of the present work was to perform a qualitative and quantitative evaluation of synaptogenesis in the developing rat cerebellum (2-45 days after birth) by immunohistochemical detection of the
Karnyushko, O. A., Zimatkin, S. M.
core   +1 more source

The Cytoplasmic MicroRNA‐Production Complex Regulates MicroRNA Sorting to Extracellular Vesicles During Synaptogenesis

Advanced Science, EarlyView.
The mechanisms of microRNA cargo sorting to extracellular vesicles, important mediators of cell communication, are not fully understood. This study reveals that the microRNA‐production machinery acts as a ‘hub’ for the sorting of microRNAs to extracellular vesicles, a process regulated by dynamic organelle interactions.
Yuzhou Zeng, Selina Luhmann, Aditi Saha, Marta Orlando, Haider Sami, Timo Glatter, Anna Antoniou   +6 more
wiley   +1 more source

Author Correction: An activity-regulated transcriptional program directly drives synaptogenesis [PDF]

Correction to: "An activity-regulated transcriptional program directly drives ...
Boyle, Alan P., Herbst, Wendy A., Reddy, Anay R., Matus, David Q., Yee, Callista, Xu, Bing, Zhang, Wan, Medwig-Kinney, Taylor N., Xiao, Yutong, Xiang, Yang Kevin, Shen, Kang, Chen, Hongwen   +11 more
core   +1 more source

KIF1A‐Mediated Axonal Transport of Netrin‐1 in iPSC‐Derived Human Forebrain Neurons

Cytoskeleton, EarlyView.
ABSTRACT Netrin‐1 is a secreted laminin‐like protein that functions as a guidance cue for axon pathfinding in development. Netrin‐1 also modulates synapse formation in developing neurons and long‐term potentiation in mature neurons. Netrin‐1 is expressed in human neurons; however, its intracellular distribution and trafficking have not been assessed ...
T. Y. Leung, J. Sidhu, A. Hsieh, Y. Ma, J. Liu, M. A. Silverman   +5 more
wiley   +1 more source

Melatonin as an Alleviator in Decabromodiphenyl Ether-Induced Aberrant Hippocampal Neurogenesis and Synaptogenesis: The Role of Wnt7a

Biomolecules
Developmental exposure to polybrominated diphenyl ethers (PBDEs), which are commonly used as flame retardants, results in irreversible cognitive impairments.
Jinghua Shen, Lu Gao, Jingjing Gao, Licong Wang, Dongying Yan, Ying Wang, Jia Meng, Hong Li, Dawei Chen, Jie Wu   +9 more
doaj   +1 more source

Generation of functional inhibitory synapses incorporating defined combinations of GABA(A) or glycine receptor subunits

Frontiers in Molecular Neuroscience, 2015
Fast inhibitory neurotransmission in the brain is mediated by wide range of GABAA receptor (GABAAR) and glycine receptor (GlyR) isoforms, each with different physiological and pharmacological properties.
Christine Laura Dixon, Yan eZhang, Joe eLynch   +2 more
doaj   +1 more source

NMDA receptor subunit composition controls synaptogenesis and synapse stabilization

, 2011
During early postnatal development in the rat hippocampus, synaptogenesis occurs in parallel with a developmental switch in the subunit composition of NMDA receptors from NR2B to NR2A.
Andres Barria, Abigail C. Gambrill
core   +1 more source

Psilocybin as a Transdiagnostic Treatment for Eating Disorders and Comorbid Psychopathology: Implications for Clinical Nosology and Research Directions

International Journal of Eating Disorders, EarlyView.
ABSTRACT Objective Eating disorders (EDs) are characterized by high rates of psychiatric comorbidity and suboptimal treatment outcomes. There remain critical gaps in research, including the exploration of effective transdiagnostic interventions. This forum article examines the potential of psilocybin treatment (PT) as a transdiagnostic intervention for
Elena Koning, Jérémie Richard, Aaron Keshen   +2 more
wiley   +1 more source

The Role of Citicoline in Neuroprotection and Neurorepair in Ischemic Stroke

Brain Sciences, 2013
Advances in acute stroke therapy resulting from thrombolytic treatment, endovascular procedures, and stroke units have improved significantly stroke survival and prognosis; however, for the large majority of patients lacking access to advanced therapies ...
Gustavo C. Román, José Álvarez-Sabín
doaj   +1 more source