Results 81 to 90 of about 35,245 (228)

Differential expression of synaptophysin and synaptoporin during pre- and postnatal development of the hippocampal network [PDF]

, 1994
The closely related synaptic vesicle membrane proteins synaptophysin and synaptoporin are abundant in the hippocampal formation of the adult rat. But the prenatal hippocampal formation contains only synaptophysin, which is first detected at embryonic day
Amaral, Assaf, Bayer, Bergmann, Bergmann, Betz, Blackstad, Blasi, Bliss, Cameron, Crawford, D. Grabs, Dyck, Feany, Frotscher, Fykse, Haug, Hollmann, Howell, Hsu, Jahn, Jahn, Johnston, Johnston, Knaus, Laemmli, Lah, Lahr, Linstedt, Linstedt, M. Bergmann, M. Brich, M. Gratzl, Marquèze-Pouey, Mundigl, O'Connor, Ovtscharoff, Oyler, P. A. Fox, Règnier-Vigouroux, Scarfone, Schiavo, Schilling, Schmied, Slomianka, Sloviter, Söllner, Th. Schuster, Thomas, Towbin, Westbrook, Zimmer   +51 more
core   +1 more source

COCHLEATA controls spatial regulation of cytokinin and auxin during nodule development

New Phytologist, EarlyView.
Nodule development defects in the coch mutant include root‐like structures, reduced colonisation, and vascular disorganisation. Summary Root nodules host nitrogen‐fixing bacteria and likely evolved through modifications of the lateral root program. Members of the NOOT‐BOP‐COCH‐LIKE transcriptional coregulator family suppress root identity in nodules ...
Karen Velandia, Muhammad Nouman Sohail, Tiana E. Scott, Alejandro Correa‐Lozano, Alannah Mannix, Eloise Foo   +5 more
wiley   +1 more source

Analysis of synaptotagmin, SV2, and Rab3 expression in cortical glutamatergic and GABAergic axon terminals

Frontiers in Cellular Neuroscience, 2012
We investigated whether cortical glutamatergic and GABAergic release machineries can be differentiated on the basis of the nature and amount of proteins they express, by performing a quantitative analysis of the degree of co-localization of synaptotagmin
Luca eBragina, Giorgia eFattorini, Silvia eGiovedì, Marcello eMelone, Federica eBosco, Fabio eBenfenati, Fabio eBenfenati, Fiorenzo eConti, Fiorenzo eConti   +8 more
doaj   +1 more source

Circulating Pro- and Anti-Inflammatory Metabolites and Its Potential Role in Rheumatoid Arthritis Pathogenesis. [PDF]

, 2020
Rheumatoid arthritis (RA) is a chronic systemic autoimmune disease that affects synovial joints, leading to inflammation, joint destruction, loss of function, and disability.
Coras, Roxana, Guma, Monica, Murillo-Saich, Jessica D   +2 more
core   +2 more sources

Genome Sequencing in 19 Families With Bladder Exstrophy and Epispadias Complex Indicates Involvement of the ADGR ‐Gene Family

American Journal of Medical Genetics Part A, Volume 200, Issue 6, Page 1286-1305, June 2026.
ABSTRACT Bladder exstrophy and epispadias complex (BEEC) is one of the most severe congenital malformations of the urogenital tract, significantly impacting continence, sexual function, and renal function. To date, the only recurrent genetic aberration identified is the 22q.11.2 microduplication, but several candidate regions and genes including ...
Agneta Nordenskjöld, Samara Alm, Jesper Eisfeldt, Jia Cao, Magnus Anderberg, Gillian Barker, Hans Matsson, Gundela Holmdahl, Anna Lindstrand, Kristina Lagerstedt‐Robinson   +9 more
wiley   +1 more source

C-terminal ECFP fusion impairs synaptotagmin 1 function: crowding out synaptotagmin 1.

The Journal of biological chemistry, 2005
To allow the monitoring of synaptotagmin 1 trafficking in vivo, we generated transgenic mice expressing a synaptotagmin 1-enhanced cyan fluorescent protein (ECFP) fusion protein under control of the Thy1 promoter. Transgenic synaptotagmin 1-ECFP is expressed throughout the brain where it localizes to synapses and marks synapses in vivo.
Han, W., Rhee, J., Maximov, A., Lin, W., Hammer, R., Rosenmund, C., Suedhof, T.   +6 more
openaire   +3 more sources

Preferential localization of a vesicular monoamine transporter to dense core vesicles in PC12 cells. [PDF]

, 1994
Neurons and endocrine cells have two types of secretory vesicle that undergo regulated exocytosis. Large dense core vesicles (LDCVs) store neural peptides whereas small clear synaptic vesicles store classical neurotransmitters such as acetylcholine ...
Edwards, RH, Evans, CJ, Liu, Y, Nirenberg, MJ, Pickel, VM, Schweitzer, ES   +5 more
core  

Association of Superoxide Dismutase 2 (SOD2) Genotype with Gray Matter Volume Shrinkage in Chronic Alcohol Users: Replication and Further Evaluation of an Addiction Gene Panel. [PDF]

, 2016
BackgroundReduction in brain volume, especially gray matter volume, has been shown to be one of the many deleterious effects of prolonged alcohol consumption. High variance in the degree of gray matter tissue shrinkage among alcohol-dependent individuals
Gitik, Miri, Goldman, David, Hodgkinson, Colin A, Meyerhoff, Dieter J, Shen, Pei-Hong, Srivastava, Vibhuti   +5 more
core   +1 more source

Identification of Alzheimer's disease subtypes and biomarkers from human multi‐omics data using subspace merging algorithm

Alzheimer's &Dementia, Volume 22, Issue 5, May 2026.
Abstract INTRODUCTION Alzheimer's disease (AD) is a heterogeneous disease with diverse disease progression trajectories and brain pathology. Identifying AD subtypes is essential for understanding AD etiology, heterogeneity, and developing precise treatment. METHODS We applied a subspace‐merging algorithm to integrate multi‐omics data from brain tissues
Ziyan Song, Xiaoqing Huang, Asha Jacob Jannu, Travis S. Johnson, Jie Zhang, Kun Huang   +5 more
wiley   +1 more source

Unveiling physiological functions of extended synaptotagmins [PDF]

Cell Cycle, 2015
The endoplasmic reticulum (ER) is an extensive membrane network in eukaryotic cells important for many cellular processes. To orchestrate cellular functions, the ER forms junctions with other organelles, where the 2 membranes are closely tethered by protein-lipid and/or protein-protein interactions within 10–25 nm.
Jen, Liou, Chi-Lun, Chang
openaire   +2 more sources