Results 41 to 50 of about 797 (157)
Emerging directions in tauopathy research
Alzheimer's &Dementia, Volume 22, Issue 6, June 2026.Abstract The Tau Global Conference 2025, hosted by the Alzheimer's Association, CurePSP, and the Rainwater Charitable Foundation, convened international experts from academia, industry, government, and philanthropy to explore advances and challenges in tauopathy research. The meeting highlighted progress across tau biology, including emerging models of
Luc Buée +41 more
wiley +1 more source
Tanycyte Gene Expression Dynamics in the Regulation of Energy Homeostasis
Frontiers in Endocrinology, 2019 Animal survival relies on a constant balance between energy supply and energy expenditure, which is controlled by several neuroendocrine functions that integrate metabolic information and adapt the response of the organism to physiological demands ...
Fanny Langlet
doaj +1 more source
Organization of the ventricular zone of the cerebellum
Frontiers in Cellular Neuroscience, 2022 The roof of the fourth ventricle (4V) is located on the ventral part of the cerebellum, a region with abundant vascularization and cell heterogeneity that includes tanycyte-like cells that define a peculiar glial niche known as ventromedial cord.
Gabriela B. Gómez-González +4 more
doaj +1 more source
Tanycytes: bloodhounds of the metabolic brain. [PDF]
Trends Endocrinol MetabConstant monitoring and fine-tuning of internal body status to maintain energy homeostasis despite changing physiological needs and environmental conditions are essential brain functions. Hypothalamic tanycytes - specialized ependymoglial cells at the interface between the blood and the brain - play crucial roles in this regulation through mechanisms ...
Rodriguez-Cortes B +6 more
europepmc +3 more sources
Synchronous presentation of prolactinoma and supratentorial tanycytic ependymoma
Journal of Neurosciences in Rural Practice, 2023 Tanycytic ependymomas mostly occur in the spinal cord and it is the rarest histological subtype of ependymoma. A 29-year-old male was referred from the infertility clinic after serum prolactin levels were found to be elevated. Magnetic resonance imaging (MRI) brain showed an irregular necrotic lesion in the periventricular region of the left parietal ...
Nair, Jishnu Narayanan +3 more
openaire +2 more sources
Cilia in Nervous System Development, Function, and Disease
MedComm – Future Medicine, Volume 5, Issue 2, June 2026.Cilia are evolutionarily conserved organelles that function as essential sensory and motility platforms in the nervous system. This review outlines key cilia‐dependent signaling pathways and their roles in neural development and function. Furthermore, it highlights how ciliary dysfunction can lead to a variety of neurological disorders, known as ...
Qingchao Li, Anqi Zhang, Ting Song
wiley +1 more source
How does type 2 diabetes modify the risk of Alzheimer's disease?
Alzheimer's &Dementia, Volume 22, Issue 5, May 2026.Abstract Type 2 diabetes (T2D) and Alzheimer's disease (AD) are both increasing exponentially worldwide. T2D has also been identified as one of 14 modifiable risk factors for dementia, but the mechanism is unknown. T2D could promote dementia via vascular or AD neuropathological changes, and mechanistic hypotheses include central insulin resistance and ...
G. T. Sutherland +7 more
wiley +1 more source
The influence of extended fasting on thyroid hormone: local and differentiated regulatory mechanisms
Frontiers in EndocrinologyThe hypometabolism induced by fasting has great potential in maintaining health and improving survival in extreme environments, among which thyroid hormone (TH) plays an important role in the adaptation and the formation of new energy metabolism ...
Xiukun Sui +11 more
doaj +1 more source
Review: “The Disappointment Dilemma: Short‐ and Long‐Term Learning From Negative Outcomes”
European Journal of Neuroscience, Volume 63, Issue 9, May 2026.The habenula routes negative‐outcome signals to VTA, RMTg, and IPN to shape aversive learning and motivation. The lateral habenula encodes acute negative prediction errors to rapidly adapt behavior to threat, fear, and avoidance. The medial habenula integrates repeated stress, drug, and aversive experiences into long‐term negative mood and expectations.
Ines Ibañez‐Tallon +4 more
wiley +1 more source
Targeting Multiple Gut‐Brain Pathways in Obesity: Rationale for Combination Pharmacotherapy
Obesity Science &Practice, Volume 12, Issue 2, April 2026.ABSTRACT Background As a disease of energy dysregulation, obesity involves metabolic, hormonal, and neural factors, the interconnection of which is referred to as the “gut‐brain axis.” Objective This review aimed to provide an overview of the clinical evidence of physiological and objective or subjective changes in eating behavior with gut hormone ...
Alexander D. Miras, Muzamil Hussain
wiley +1 more source