Results 41 to 50 of about 373 (115)
, 2022 Hypothalamic tanycytes are neural stem and progenitor cells, but little is known of how they are regulated. Here we provide evidence that the cell adhesion molecule, NrCAM, regulates tanycytes in the adult niche.
Fran Ebling (12367651) +13 more
core +1 more source
ENT1 inhibition links oligodendrocyte lipid metabolism to connectivity in tauopathy
Alzheimer's &Dementia, Volume 22, Issue 9, September 2026.Abstract INTRODUCTION Metabolic dysfunction, altered adenosine signaling, and white matter abnormalities are implicated in tauopathies, but their relationship to network disconnection remains unclear. Myelinating oligodendrocytes may represent a metabolically vulnerable hub linking these processes to circuit dysfunction.
Ching‐Pang Chang +7 more
wiley +1 more source
Single‐cell atlas of neuroglial dynamics in SNCA‐A53T Parkinson's disease mouse model
Animal Models and Experimental Medicine, Volume 9, Issue 8, Page 1613-1632, August 2026.We performed single‐cell RNA sequencing of midbrain and striatal tissues from SNCA‐A53T Parkinson's disease (PD) mice, revealing glia‐enriched PD‐risk gene signatures and disease‐specific subpopulations. Transcriptional dysregulation of key TFs (e.g., Rorb, Foxc1) and enhanced neuroinflammatory signaling (SEMA, CCL, MIF) were identified.
Binqing Qin +7 more
wiley +1 more source
Organization of the ventricular zone of the cerebellum
Frontiers in Cellular Neuroscience, 2022 The roof of the fourth ventricle (4V) is located on the ventral part of the cerebellum, a region with abundant vascularization and cell heterogeneity that includes tanycyte-like cells that define a peculiar glial niche known as ventromedial cord.
Gabriela B. Gómez-González +4 more
doaj +1 more source
Glia, Volume 74, Issue 8, August 2026.Single‐nucleus multiomic profiling of postmortem brain reveals coordinated immune, metabolic, and epigenomic reprogramming in glia of people with HIV consistent with maladaptive trained immunity sustaining neuroinflammation in HAND. ABSTRACT HIV‐associated neurocognitive disorders (HAND) remain prevalent in people with HIV (PWH) despite effective ...
Siera Martinez +8 more
wiley +1 more source
, 2022 Hypothalamic tanycytes are neural stem and progenitor cells, but little is known of how they are regulated. Here we provide evidence that the cell adhesion molecule, NrCAM, regulates tanycytes in the adult niche.
Fran Ebling (12367651) +13 more
core +1 more source
Addiction Biology, Volume 31, Issue 7, July 2026.Thirty‐three AUD patients enrolled in an Alcohol Detoxification Program at Hospital Universitario 12 de Octubre (Madrid, Spain) and 34 healthy controls were followed for 12 months. AUD patients exhibited impaired general cognitive functioning, elevated plasma LPS and altered apolipoproteins (APOAI, APOAE, APOAJ, APOAM), which progressively normalized ...
Berta Escudero +3 more
wiley +1 more source
The influence of extended fasting on thyroid hormone: local and differentiated regulatory mechanisms
Frontiers in EndocrinologyThe hypometabolism induced by fasting has great potential in maintaining health and improving survival in extreme environments, among which thyroid hormone (TH) plays an important role in the adaptation and the formation of new energy metabolism ...
Xiukun Sui +11 more
doaj +1 more source
Emerging directions in tauopathy research
Alzheimer's &Dementia, Volume 22, Issue 6, June 2026.Abstract The Tau Global Conference 2025, hosted by the Alzheimer's Association, CurePSP, and the Rainwater Charitable Foundation, convened international experts from academia, industry, government, and philanthropy to explore advances and challenges in tauopathy research. The meeting highlighted progress across tau biology, including emerging models of
Luc Buée +41 more
wiley +1 more source
Schematic illustration of axonal uptake and regulation of T3 in the mediobasal hypothalamus.
, 2013 We suggest that T3 generated by D2 is released from tanycyte processes and taken up by MCT8 into axons of hypophysiotropic neurons. T3 concentrations are subjected to local regulation by D3-containing axon varicosities (At1), but absent in D3-negative ...
László Barna (5064671) +19 more
core +1 more source