Results 21 to 30 of about 797 (157)
Txnip, Tanycytes, and Torpor [PDF]
As biologists, we are brought up with the concept that mammals are homeothermic, so they tightly regulate body temperature through a complex balance between thermogenesis and heat conservation and dissipation mechanisms. One of the remarkable features of the natural world is that many mammals can also show torpor or hibernation.
Francis J P, Ebling, Ricardo, Samms
openaire +2 more sources
Glial functions in the blood-brain communication at the circumventricular organs
The circumventricular organs (CVOs) are located around the brain ventricles, lack a blood-brain barrier (BBB) and sense blood-derived molecules. This review discusses recent advances in the importance of CVO functions, especially glial cells transferring
Seiji Miyata
doaj +1 more source
Endogenous Neural Stem Cell Mediated Oligodendrogenesis in the Adult Mammalian Brain
Oligodendrogenesis is essential for replacing worn-out oligodendrocytes, promoting myelin plasticity, and for myelin repair following a demyelinating injury in the adult mammalian brain.
Daniel Z. Radecki, Jayshree Samanta
doaj +1 more source
Irx3 and Irx5 - Novel Regulatory Factors of Postnatal Hypothalamic Neurogenesis
The hypothalamus is a brain region that exhibits highly conserved anatomy across vertebrate species and functions as a central regulatory hub for many physiological processes such as energy homeostasis and circadian rhythm. Neurons in the arcuate nucleus
Zhengchao Dou +4 more
doaj +1 more source
Background: Tanycytic ependymoma (TE) (WHO grade II) is a rare and morphologically distinct variant of ependymoma with only 77 cases reported worldwide so far. Variable clinical and radio-pathological features lead to misdiagnosis as WHO grade 1 tumors. On imaging, differentials of either schwannoma, meningioma, low-grade glial
Pragya, Jain +5 more
openaire +2 more sources
The role of tanycytes in hypothalamic glucosensing [PDF]
AbstractTanycytes are elongated hypothalamic glial cells that cover the basal walls of the third ventricle; their apical regions contact the cerebrospinal fluid (CSF), and their processes reach hypothalamic neuronal nuclei that control the energy status of an organism. These nuclei maintain the balance between energy expenditure and intake, integrating
Elizondo-Vega, Roberto +5 more
openaire +4 more sources
Cooperative tanycytes fuel the neuronal tank
Tanycytes are specialized radial glial cells of the hypothalamus that have emerged as important players that sense and respond to fluctuations in whole-body energy status to maintain energy homeostasis. However, the underlying mechanisms by which tanycytes influence energy balance remain incompletely understood.
Roberta Haddad-Tóvolli, Marc Claret
openaire +2 more sources
Background: Circumventricular organs (CVOs) are specialized structures border the brain ventricles and lack the blood-brain barrier. These CVOs are lined by specialized ependymal cells (ECs) called tanycyte.
Haider F. Jawad +2 more
doaj +6 more sources
Single-Cell RNA-Seq Reveals Hypothalamic Cell Diversity
The hypothalamus is one of the most complex brain structures involved in homeostatic regulation. Defining cell composition and identifying cell-type-specific transcriptional features of the hypothalamus is essential for understanding its functions and ...
Renchao Chen +3 more
doaj +1 more source
ATP‐mediated glucosensing by hypothalamic tanycytes [PDF]
Non‐technical summary The hypothalamus contains key neural circuits involved in the control of feeding and energy balance. Stimulated by the inexorable rise of obesity, there has been intense study of these neural circuits. However, the possible role of non‐neuronal cells in the brain has not been extensively considered.
Frayling, Cameron +2 more
openaire +2 more sources

