Results 191 to 200 of about 110,474 (301)

Morphometric Similarity Patterning of Amyloid-β and Tau Proteins Correlates with Transcriptomics in the Alzheimer's Disease Continuum. [PDF]

Int J Mol Sci
Brusini L, Dolci G, Pini L, Cruciani F, Pizzagalli F, Provero P, Menegaz G, Boscolo Galazzo I, Alzheimer’s Disease Neuroimaging Initiative.   +8 more
europepmc   +1 more source

Modeling the dynamical interaction Tau Proteins - microtubules

, 2018
La maladie d’Alzheimer, de nombreux syndromes parkinsoniens, certaines démences fronto-temporales telle que la maladie de Pick sont des exemples de maladies neurodégénératives appelées « tauopathies » qui sont caractérisées par la présence d’agrégats ...
Hervy, Jordan
core  

Condition‐Associated Pattern Extraction and Recovery From Multi‐Condition Single‐Cell RNA‐seq Data With CAPER

Advanced Science, EarlyView.
Decoupling biological signals from unwanted variation in multi‑condition single‑cell RNA sequencing data remains challenging. CAPER disentangles condition‑associated biological effects from sample heterogeneity through matrix factorization, producing interpretable latent factors and a batch‑corrected expression matrix.
Ye Li, Jin Ning, An Wang, Minxi Shi, Yuanze Chen, Guoliang Liu, Shiquan Sun   +6 more
wiley   +1 more source

Klotho null mutation leads to retinal degeneration characterized by functional impairment, gliosis, and deposition of amyloid-beta and hyperphosphorylated tau proteins. [PDF]

PLoS One
Chen ZJ, Wu CY, Hsiao FY, Ma JC, Lai G, Chang HH, Lin DP.   +6 more
europepmc   +1 more source

AI‐Assisted Digital Single‐Molecule Activity Tracker for Decoupling Intrinsic Heterogeneity from Photo‐Oxidative Damage in High‐Photon‐Flux Enzymology

Advanced Science, EarlyView.
Employing a digital single‐molecule activity tracker (dSMAT), this research demonstrates that high‐photon‐flux irradiation drives progressive oxidative scarring in polymerases. Unlike simple thermal denaturation, real‐time kinetic tracking dynamically visualizes enzymes degrading into multiple impaired subpopulations.
Anran Zheng, Qi Yang, Jinze Li, Fuqiang Ma, Xuefeng Wang, Zhen Guo, Chuanyu Li, Dongshu Li, Jia Yao, Zhiqi Zhang, Wei Zhang, Lianqun Zhou   +11 more
wiley   +1 more source

The Role of Alpha-Synuclein and Tubulin-Associated Unit (Tau) Proteins in the Diagnosis, Prognosis, and Treatment of Parkinson's Disease: A Systematic Review. [PDF]

Cureus
Lin YM, Banoth D, Wali MH, Bekova K, Abdulla N, Gurugubelli S, Khan S.   +6 more
europepmc   +1 more source

Cavity Microelectrode Arrays for Electrical Recordings From Neurons

Advanced Electronic Materials, EarlyView.
Microelectrode arrays (MEAs) are used to study electrophysiological activity. However, their signals are small with high noise. By adding a 100‐nanometer‐high cavity above the electrode, which reduces impedance without affecting resolution, we improve signal quality.
Johannes Lewen, Bernhard Wolfrum, Andreas Offenhäusser   +2 more
wiley   +1 more source

Pilot Study of the Total and Phosphorylated Tau Proteins in Early-Stage Multiple Sclerosis. [PDF]

Medicina (Kaunas)
Masiulienė I, Pampuščenko K, Žemgulytė G, Bilskienė D, Borutaitė V, Balnytė R.   +5 more
europepmc   +1 more source

Dynamical decoration of stabilized-microtubules by Tau-proteins. [PDF]

Sci Rep, 2019
Hervy J, Bicout DJ.
europepmc   +1 more source

Foreign labor, peer‐networking and agricultural efficiency in the Italian dairy sector

Agribusiness, EarlyView.
Abstract While the presence of immigrants in the agricultural sector is widely acknowledged, the empirical evidence on its economic consequences is lacking, especially from a microeconomic perspective. Using the Farm Accountancy Data Network panel data for Italian dairy farms in the period 2008–2018, the present study investigates the relationship ...
Federico Antonioli, Simone Severini, Mauro Vigani   +2 more
wiley   +1 more source