Results 201 to 210 of about 104,850 (261)

Molecular Engineering Boosts Photon‐Activated Immunotherapy for Prostate Cancer Through Concurrent Pyroptosis and cGAS‐STING Pathway Activation

Angewandte Chemie, EarlyView.
The engineered DTSe‐based photosensitizer, DZTSe, emerges as an avant‐garde molecular entity, which can distribute to both the endoplasmic reticulum and mitochondria to concurrently trigger pyroptosis and activate the cGAS‐STING pathway. This dual‐action strategy effectively reprograms the tumor microenvironment, enabling potent eradication of primary ...
Cheng Zhang, Xiaolan Yin, Jeongyeon Hong, Qixian Chen, Weijie Chi, Jingyun Wang, Juyoung Yoon, Haidong Li   +7 more
wiley   +2 more sources

Caging Polyhalide Anions in Polycyclodextrin for Long‐Lasting Aqueous Zinc‐Iodine Batteries

Angewandte Chemie, EarlyView.
We demonstrated poly(β‐cyclodextrin) gel as an ideal host material that effectively contains and releases polyhalide anions in aqueous zinc‐iodine batteries. Such a unique host‐guest chemistry prevents the shuttle effect of polyhalides. The corresponding batteries can operate via both 2e and 4e storage, attaining 60,000 cycles with more than 99% and 85%
Shangxu Jiang, Zhipeng Pei, Yanlin Shi, Kai Zhang, Justin M. Chalker, Sara J. Fraser‐Miller, Michelle L. Coote, Zhongfan Jia   +7 more
wiley   +2 more sources

Tau profiling of brain extracellular vesicles reveals PHF6 peptide as core for pathological tau seeding in Alzheimer's disease. [PDF]

J Biomed Sci
Oosterlynck M, Fichter L, Leroux E, Eddarkaoui S, Bouillet T, Lefebvre C, Nguyen M, Maurage CA, Accart B, Dupré E, Landrieu I, Danis C, Lehmann S, Vialaret J, Buée L, Hirtz C, Colin M.   +16 more
europepmc   +1 more source

Meta-cancer phosphoproteomic analysis unveils association of Tau phosphosites with DNA damage response. [PDF]

Front Syst Biol
Poojari TR, Dcunha L, Mahin A, Gopalakrishnan AP, Ahmed M, Sekhar PS, Ummar S, John L, Modi PK, Soman S, Raju R, Palollathil A.   +11 more
europepmc   +1 more source

Morphometric analysis of postnatal lung development in the gray short‐tailed opossum (Monodelphis domestica): An ultrastructural study

The Anatomical Record, EarlyView.
Abstract An ultrastructural morphometric analysis of the postnatal development of the lung in the gray short‐tailed opossum (Monodelphis domestica) has been conducted to evaluate the morphofunctional status of this poorly developed marsupial lung immediately following parturition.
Kirsten Ferner
wiley   +1 more source

SynCAR platform for capturing neuronal synaptic proteopathic seeds. [PDF]

iScience
Sebastian RM, Kupp R, Nanavati D, Parfentev I, Krzystek TJ, Romanul N, Yanamandra K, Preiss CN, Manos JD, Wu HY, Volkova A, Crescenti S, Titterton K, Welker AM, Townsend M, Karran E, Langlois X, Wu JW.   +17 more
europepmc   +1 more source

From development to dissection: A coaching‐focused workshop for anatomy educators from the viewpoint of the coaches

Anatomical Sciences Education, EarlyView.
Abstract The use of different coaching models can provide an effective environment for skill learning. The Anatomical Donor Stewardship (ADS) Coaching subcommittee, within the Human Anatomy and Physiology Society (HAPS), developed and held an inaugural Coaching workshop for human anatomical dissection for HAPS members at the 2025 HAPS Annual Conference
Danielle N. Edwards, Bobbie J. Leeper, Kelsey E. Stevens, Jonathan J. Wisco, Abbey Breckling, Rhiannon E. Robinson, Jeremy J. Grachan   +6 more
wiley   +1 more source

Biophysical assessment of the molecular mechanisms of Tau aggregation and its role in Alzheimer's disease. [PDF]

Protein Sci
Skrehot JT, Kurouski D.
europepmc   +1 more source

Label-free optical observation of disordered-to-ordered transitions in single intrinsically disordered proteins. [PDF]

NPJ Biosens
Zargarbashi S, Dominguez C, Peters M, Yousefi A, Munday S, Wang Y, Chatterjee S, Hudson AJ, Gordon R, Mellor CJ, Xu L, Rahmani M, Ying C.   +12 more
europepmc   +1 more source