Results 41 to 50 of about 14,323,807 (202)

Developing TPACK: Envisioning Technological Pedagogical Reasoning

open access: yes, 2016
In this chapter, we explore and propose that teachers undertake technological pedagogical reasoning, which can assist in deepening an understanding of how we can represent the knowledge base of teaching.
Sim, Cheryl   +5 more
core   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Educational Neuroscience Training for Teachers’ Technological Pedagogical Content Knowledge Construction

open access: yesFrontiers in Psychology, 2021
The attention to the laws of the brain and the mechanism of learning in the smart education era becomes the starting point for the convergence and development of education and neuroscience, which also inspired educational neuroscience (EN) affecting the ...
Yulu Cui, Hai Zhang
doaj   +1 more source

A bibliometric analysis of research on Technological Pedagogical Content Knowledge on in-service teachers in higher education [PDF]

open access: yes
Technological Pedagogical Content Knowledge illustrates the interconnected nature of knowledge required to effectively integrate technology in enhancing student learning. While numerous review studies on Technological Pedagogical Content Knowledge exist,
Jeyaraj, Joanna Joseph   +3 more
core   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

TPCK (Technological Pedagogical and Content Knowledge) Competence for Educator: A Literature Review

open access: yesEdukasia
This study aimed to analyze the competence of TPCK (Technological Pedagogical and Content Knowledge) in teachers through a literature review. The research conducted literature searches through academic databases, journals, books, and other sources of ...
Yudis Korin Sihanita   +2 more
doaj   +1 more source

Does the TPACK framework help to design a more engaging learning environment? [PDF]

open access: yes, 2011
This paper describes an attempt to design an e-learning course within a framework that combines theoretical underpinnings with pedagogy and content knowledge. It focuses on how a university lecturer can facilitate learning that integrates pedagogical and
Roberts, P., Maor, D.
core  

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

Development of Technological, Pedagogical and Content Knowledge Based Learning Media

open access: yesJurnal Teknologi Pendidikan, 2023
Problems in education are very diverse, one of which is that students are lazy to read and do not understand how to draw the right conclusions so that this has an impact on the learning achievement of Indonesian language students in grade VI SDN Petojo ...
Nurrohmatul Amaliyah
doaj   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

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