Results 41 to 50 of about 139,652 (262)

Development of Technological, Pedagogical and Content Knowledge Based Learning Media

open access: yesJurnal Teknologi Pendidikan, 2023
Problems in education are very diverse, one of which is that students are lazy to read and do not understand how to draw the right conclusions so that this has an impact on the learning achievement of Indonesian language students in grade VI SDN Petojo ...
Nurrohmatul Amaliyah
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Research on the Model of Technological Pedagogical Content Knowledge of Teachers (TPACK)

open access: yesZhishi guanli luntan, 2019
[Purpose/significance] TPACK framework doesn’t describe the level of knowledge, and the generation and transformation process of knowledge. This paper constructed a TCP teacher knowledge system model to describe the TPACK structure of teachers more ...
Zhan Rui
doaj   +1 more source

Analisis Kemampuan Technological Pedagogical Content Knowledge Mahasiswa Calon Guru Kimia

open access: yesJIPI (Jurnal IPA dan Pembelajaran IPA), 2022
The effectiveness of a learning is determined by the combination of various dimensions of knowledge with technology carried out by teachers. This study aims to analyse the TPACKs’ skills of chemistry education students of FKIP Untan who will become the ...
Maria Ulfah*, Erlina Erlina
doaj   +1 more source

Discerning protein pools by selective staining with self‐labeling tags

open access: yesFEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

DEVELOPING TECHNOLOGICAL PEDAGOGICAL CONTENT KNOWLEDGE OF ENGLISH LANGUAGE TEACHERS

open access: yesJournal on Efficiency and Responsibility in Education and Science, 2013
Integration of information and communication technology into other than Information Technology subjects taught at schools of all levels in the Czech Republic has become of great importance.
CARBOVÁ, Anna, BETÁKOVÁ, Lucie
doaj   +1 more source

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