Results 51 to 60 of about 14,323,807 (202)

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

FEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

Analisis Kemampuan Technological Pedagogical Content Knowledge Mahasiswa Calon Guru Kimia

JIPI (Jurnal IPA dan Pembelajaran IPA), 2022
The effectiveness of a learning is determined by the combination of various dimensions of knowledge with technology carried out by teachers. This study aims to analyse the TPACKs’ skills of chemistry education students of FKIP Untan who will become the ...
Maria Ulfah*, Erlina Erlina
doaj   +1 more source

Unlocking the potential of cell‐permeable nanobodies for intracellular applications

FEBS Letters, EarlyView.
This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés, Luise Franz, Christian P.R. Hackenberger   +2 more
wiley   +1 more source

Assessing pre-service science teachers' technological pedagogical content knowledge (TPACK) through observations and lesson plans [PDF]

, 2016
WOS: 000373840100007Background: Technological pedagogical content knowledge (TPACK) is critical for effective teaching with technology. However, generally science teacher education programs do not help pre-service teachers develop TPACK.
Bilici, Sedef Canbazoğlu, Yamak, Havva, Guzey, Sedef, Canbazoğlu Bilici, Sedef, Guzey, Sıddıka Selcen   +4 more
core   +1 more source

Introducing technological pedagogical content design: A model for transforming knowledge into practice

, 2021
With the extraordinary growth of both mis- and disinformation, it has become even more vital to prepare content to provide accurate information so that users receive concepts correctly.
Hosseini, Zahra, Hytönen, Kimmo, Kinnunen, Jani, Kimmo Hytönen, Zahra Hosseini, Jani Kinnunen   +5 more
core   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Technological Pedagogical and Content Knowledge of Biology Prospective Teachers

Biosaintifika: Journal of Biology & Biology Education, 2017
This research was conducted for analyzing Technological Pedagogical and Content Knowledge (TPACK) of biology prospective teachers in Riau Province. The study was carried out to fulfill Indonesian Government’s policy on Indonesian Qualification Framework (
Evi Suryawati, Mariani Natalina Linggasari, Arnentis Arnentis   +2 more
doaj   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

Molecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou, Niki Tzenaki, Anna Tsapara, Maria Tzardi, Evangelia A. Papakonstanti   +4 more
wiley   +1 more source

DEVELOPING TECHNOLOGICAL PEDAGOGICAL CONTENT KNOWLEDGE OF ENGLISH LANGUAGE TEACHERS

Journal on Efficiency and Responsibility in Education and Science, 2013
Integration of information and communication technology into other than Information Technology subjects taught at schools of all levels in the Czech Republic has become of great importance.
CARBOVÁ, Anna, BETÁKOVÁ, Lucie
doaj   +1 more source