Results 161 to 170 of about 25,496 (206)

Editorial: Tumor-associated tertiary lymphoid structures response during immunotherapy

Frontiers in Immunology
Ileana Soto Mauldin, Christine Mall Minnar, Antoine Italiano, Antoine Italiano   +3 more
openaire   +3 more sources

Radiotherapy-derived engineered stem cell exosomes improve anti-glioma immunotherapy by promoting the formation of tertiary lymphoid structure and improve the release of type I interferon. [PDF]

J Nanobiotechnology
Li M, Lu L, Bao Q, Zhou M, Nie B, Liu Y, Shu K, Lei T, Zhu M.   +8 more
europepmc   +1 more source

Lymphocyte homing and recirculation with tumor tertiary lymphoid structure formation: predictions for successful cancer immunotherapy. [PDF]

Front Immunol
Tian W, Wei W, Qin G, Bao X, Tong X, Zhou M, Xue Y, Zhang Y, Shao Q.   +8 more
europepmc   +1 more source

Development of a tertiary lymphoid structure-based prognostic model for breast cancer: integrating single-cell sequencing and machine learning to enhance patient outcomes. [PDF]

Front Immunol
Zhang X, Li L, Shi X, Zhao Y, Cai Z, Ni N, Yang D, Meng Z, Gao X, Huang L, Wang T.   +10 more
europepmc   +1 more source

Tertiary lymphoid structure-related score as a predictor for survival prognosis and immunotherapy response in head and neck squamous cell carcinoma. [PDF]

Front Immunol
Wu F, Cao H, Ren S, Wu J, Liu X, Li Q, Xu Q, Chen J, Wang R, Chen S, Kuang S, Xia B, Li Y, Wang L, Li J, Li B, Li J, Lan T.   +17 more
europepmc   +1 more source

Associations between tertiary lymphoid structure density and immune checkpoint inhibitor efficacy in solid tumors: systematic review and meta-analysis. [PDF]

Front Immunol
Jiang B, Wu Z, Zhang Y, Yang X.
europepmc   +1 more source

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Tertiary lymphoid structures in cancer

Science, 2022
Tertiary lymphoid structures in cancer Tertiary lymphoid structures (TLSs) are lymphoid formations that are found in nonlymphoid tissues. TLS can develop in inflamed tissues and are associated with chronic inflammatory disorders, autoimmunity, and cancer. In the setting of tumors, TLSs facilitate the influx of immune cells into the tumor site
Ton N. Schumacher, Daniela S. Thommen
openaire   +4 more sources

Tertiary lymphoid structures in cancer and beyond

Trends in Immunology, 2014
Tertiary lymphoid structures (TLS) are ectopic lymphoid formations found in inflamed, infected, or tumoral tissues. They exhibit all the characteristics of structures in the lymph nodes (LN) associated with the generation of an adaptive immune response, including a T cell zone with mature dendritic cells (DC), a germinal center with follicular ...
Marie-Caroline, Dieu-Nosjean, Jérémy, Goc, Nicolas A, Giraldo, Catherine, Sautès-Fridman, Wolf Herman, Fridman   +4 more
openaire   +4 more sources

Tertiary lymphoid structures in anticancer immunity

Nature Reviews Cancer
Tertiary lymphoid structures (TLS) are transient ectopic lymphoid aggregates where adaptive antitumour cellular and humoral responses can be elaborated. Initially described in non-small cell lung cancer as functional immune lymphoid structures associated with better clinical outcome, TLS have also been found in many other carcinomas, as well as ...
Jean-Luc Teillaud, Ana Houel, Marylou Panouillot, Clémence Riffard, Marie-Caroline Dieu-Nosjean   +4 more
openaire   +4 more sources

Tertiary lymphoid structures improve immunotherapy and survival in melanoma

Nature, 2020
Checkpoint blockade therapies that reactivate tumour-associated T cells can induce durable tumour control and result in the long-term survival of patients with advanced cancers1. Current predictive biomarkers for therapy response include high levels of intratumour immunological activity, a high tumour mutational burden and specific characteristics of ...
Cabrita, Rita, Lauss, Martin, Sanna, Adriana, Donia, Marco, Skaarup Larsen, Mathilde, Mitra, Shamik, Johansson, Iva, Phung, Bengt, Harbst, Katja, Vallon-Christersson, Johan, van Schoiack, Alison, Lövgren, Kristina, Warren, Sarah, Jirström, Karin, Olsson, Håkan, Pietras, Kristian, Ingvar, Christian, Isaksson, Karolin, Schadendorf, Dirk, Schmidt, Henrik, Bastholt, Lars, Carneiro, Ana, Wargo, Jennifer A., Svane, Inge Marie, Jönsson, Göran   +24 more
openaire   +8 more sources