Results 11 to 20 of about 260,137 (386)
The Alterations in and the Role of the Th17/Treg Balance in Metabolic Diseases
Frontiers in Immunology, 2021 Chronic inflammation plays an important role in the development of metabolic diseases. These include obesity, type 2 diabetes mellitus, and metabolic dysfunction-associated fatty liver disease.
Siwen Zhang +6 more
semanticscholar +1 more source
Immunological Medicine, 2022 Th17 cells are implicated in the pathogenesis of several autoimmune diseases. During the inflammation, Th17 cells exposed to IL-12 can shift towards the Th1 phenotype. These shifted cells are defined as ‘non-classic Th1 cells’.
Bo-Young Shin +5 more
doaj +1 more source
Th17 cells and HIV infection [PDF]
Current Opinion in HIV and AIDS, 2010 This review summarizes the recent literature about the potential perturbation and role of Th17 cells in HIV pathogenesis. We discuss the recent findings on Th17 deficiency in HIV/simian immunodeficiency virus (SIV) infection and how this deficiency may impact the mucosal host defenses, potentially contributing to chronic immune activation.Th17 cells ...
Aimee El-Hed, Derya Unutmaz
openalex +4 more sources
Lactate induces metabolic and epigenetic reprogramming of pro‐inflammatory Th17 cells
EMBO Reports, 2022 Increased lactate levels in the tissue microenvironment are a well‐known feature of chronic inflammation. However, the role of lactate in regulating T cell function remains controversial.
Aleksandra Lopez Krol +14 more
semanticscholar +1 more source
Frontiers in Immunology, 2020 During pregnancy, various immune effectors and molecules participating in the immune-microenvironment establish specific maternal tolerance toward the semi-allogeneic fetus.
Wen-juan Wang +3 more
semanticscholar +1 more source
Changes in Bone Metabolism and Structure in Primary Hyperparathyroidism
Acta Medica Bulgarica, 2020 Parathyroid hormone (PTH) is a key regulator of bone turnover. Depending on the duration of action, the hormone causes catabolic and anabolic effects by binding with specific receptors (PTHR1) in the bone.
Yankova I., Shinkov A., Kovatcheva R.
doaj +1 more source
Human gut bacteria produce TH17-modulating bile acid metabolites
bioRxiv, 2021 The microbiota plays a pivotal role in gut immune homeostasis. Bacteria influence the development and function of host immune cells, including T helper cells expressing interleukin-17a (TH17 cells).
Donggi Paik +18 more
semanticscholar +1 more source
Features of peripheral blood Treg and Th17 subsets during physiological pregnancy [PDF]
Exploration of ImmunologyAim: Regulatory T (Treg) cells and interleukin-17-producing T helper (Th17) cells play a critical role in successful pregnancy. Treg and Th17 cells differentiate predominantly in the thymus.
Olga Gorbunova +3 more
doaj +1 more source
Concomitant Expression of IL-6 and TGF-β Cytokines and their Receptors in Peripheral Blood of Patients with Multiple Sclerosis: The Effects of INFβ Drugs [PDF]
Iranian Journal of Immunology, 2022 Background: Concomitant signals from IL-6 and TGF-β have a central role in the Th17 cells development and differentiation, and these cells are the main promoters of demyelinating inflammation in the central nervous system (CNS) resulting in multiple ...
Parisa Maleki +2 more
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How to treat a patient with psoriatic arthritis and chronic lymphocytic leukemia? [PDF]
Exploration of Musculoskeletal DiseasesA 76-year-old male patient who has been suffering from psoriatic arthritis (PsA) for 15 years was diagnosed with chronic lymphocytic leukemia (CLL) 18 months ago.
Jürgen Braun +2 more
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