Results 191 to 200 of about 260,137 (386)
The design of the entire paper. Green part represents the bioinformatics analysis approach. Yellow part represents the ideas of animal experiment. Abstract Background Chronic obstructive pulmonary disease (COPD) is a type of chronic respiratory disease.
Xuejing Luan +5 more
wiley +1 more source
Pro‐Inflammatory c‐Met+ CD4 T Cells in Multiple Sclerosis
Objective Hepatocyte growth factor (HGF) binds exclusively the c‐Met surface receptor, and the HGF/c‐Met axis regulates T cell function in autoimmune diseases. We analyzed c‐Met expression on human CD4 T cells in the blood and cerebrospinal fluid (CSF) from patients with multiple sclerosis (MS) versus non‐inflammatory neurological disease (NIND), to ...
Gautier Breville +6 more
wiley +1 more source
Th17 cells have crucial functions in host defense, and dysregulated Th17 responses mediate a variety of autoimmune and inflammatory conditions. Th17 cells coexpress IL-22, and its receptor is expressed on epidermal keratinocytes. IL-17 and /or IL-22 induce the production of certain cytokines, chemokines and antimicrobial peptides by keratinocytes, and ...
openaire +3 more sources
Cladribine tablets are approved for relapsing multiple sclerosis, mediating their clinical effect by moderately depleting lymphocytes. In a prospective, monocentric study including 22 patients completing 2 annual cycles of cladribine, B‐ and T‐cell receptor repertoires and relapse activity were assessed at baseline and after 24 months. T‐cell clonality
Tilman Schneider‐Hohendorf +8 more
wiley +1 more source
Except the widely accepted use of immune Checkpoint inhibitors in the treatment of microsatellite instability-high (MSI-H) mismatch repair-deficient (MMRd) CRCs representing about 5% of all metastatic (m)CRC patients, new strategies are applied to cure ...
Gulubova M. +3 more
doaj +1 more source
The emerging role of aryl hydrocarbon receptor in the activation and differentiation of Th17 cells
Eszter Baricza +4 more
openalex +2 more sources
This review explains how biomaterials and nanoparticles can be used to induce or modulate tertiary lymphoid structures (TLSs), which are ectopic immune hubs that form in nonlymphoid tissues during chronic disease and cancer. By comparing different methods, the article highlights design principles for modeling TLSs or recapitulating specific TLS ...
Shaza Karaman, Mei ElGindi, Jeremy Teo
wiley +1 more source
B cells control lupus autoimmunity by inhibiting Th17 and promoting Th22 cells [PDF]
Ji Yang, Xue Yang, Luman Wang, Ming Li
openalex +1 more source
Serum Th1, Th2 and Th17 cytokine profiles and alpha‐enolase levels in recurrent aphthous stomatitis [PDF]
Kemal Özyurt +7 more
openalex +1 more source

