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Synthesis of 4-(2-Methylthiazol-4-yl)-Hexahydroquinoline and 1,4-Dihydropyrimidin Derivatives [PDF]
A series of new hexahydroquinoline and 1,4-dihydropyrimidine derivatives were synthesized. Condensation of 2-methyl- thiazole-4-carboxaldehyde (1) with 1,3-cyclohexanedione and alkyl 3- aminocrotonate afforded 4-(2-methyl-thiazol-4-yl)-hexahydroquinoline
A. Shafiee
doaj
Reactions of hydrazonoyl halides and each of methyl 2-(1-(5-methyl-1-phenyl-1H-1,2,3-triazol-4-yl)ethylidene)hydrazine-1-carbodithioate and 2-(1-(5-methyl-1-phenyl-1H-1,2,3-triazol-4-yl)ethylidene)hydrazine-1-carbothioamide afforded 2-(1-(5-methyl-1 ...
Sobhi M. Gomha+2 more
doaj +1 more source
Selective anti-malarial minor groove binders [PDF]
A set of 31 DNA minor groove binders (MGBs) with diverse structural features relating to both physical chemical properties and DNA binding sequence preference has been evaluated as potential drugs to treat Plasmodium falciparum infections using a ...
Avery, Vicky M.+4 more
core +1 more source
A ketol‐acid reductoisomerase inhibitor that has antituberculosis and herbicidal activity.
Ketol‐acid reductoisomerase (KARI) is a target for the development of new biocidal agents. This is based on its essential role in branched chain amino acid biosynthesis in plants and microorganisms, and its absence in animals. The lack of success in developing KARI inhibitors as biocides may be because the inhibitors assessed to date compete directly ...
Luke William Guddat+9 more
wiley +1 more source
Factors Affecting Cooked Chicken Meat Flavour: A Review [PDF]
Flavour, one of the most important factors affecting consumers’ meat-buying behaviour and preferences, comprises mainly of taste and aroma. The cooked meat flavour, that is important from the producer and consumer point of view, is affected by several ...
Ahn, Dong+4 more
core +3 more sources
N‐heteroaromatic alkyl alcohols and amines are inherently unstable in acidic and/or basic solution due to an irreversible dehydrogenation that proceeds from a minority tautomer. In many cases, this reaction results in quantitative oxidation to the corresponding aldehyde, providing a simple, convenient, and green approach for preparing versatile ...
Omid Ghasemloo+4 more
wiley +1 more source
Synthesis and evaluation of novel 2,4-disubstituted arylthiazoles against T. brucei. [PDF]
The design, synthesis and pharmacological evaluation of the 4-substituted-2-[3-(adamant-1-yl)-4-fluorophenyl]thiazoles 1a-j, the 4-substituted-2-[4-(adamant-1-yl)phenyl]thiazoles 2a-h, the 2-substituted-4-[4-(adamant-1-yl)phenyl]thiazoles 3a-e, the N ...
Georgiadis, Markos-Orestis+5 more
core +1 more source
TzTz derivatives are promising materials for flexible optoelectronic and sensing applications due to their easy synthesis, tunable properties, and stability. This study analyzes 10 TzTz derivatives, detailing their synthesis, spectroscopic characterization (FTIR, NMR, UV‐Vis), fluorescence behavior, and synchrotron XANES findings, showcasing their ...
Karolina Gutmańska+9 more
wiley +1 more source
It is well known that growth and morphogenesis of plant tissue cultures can be improved by small amounts of some organic compounds. Heterocyclic compounds such as chromanones and thiazoles derivatives, valuable because of their potential biological ...
OANA-IRINA PATRICIU +6 more
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N-Propargylamines: versatile building blocks in the construction of thiazole cores
Thiazoles and their hydrogenated analogues are not only key structural units in a wide variety of natural products but they also constitute important building blocks in medicinal chemistry.
S. Arshadi+4 more
doaj +1 more source