Results 91 to 100 of about 1,246 (203)
Advances in Chemistry of Isothiocyanate-derived Colourants
This study is focused on the reactions of isothiocyanates (ITCs) in the presence of amino compounds leading to coloured structures via substituted 2-thiohydantoins.
K. Cejpek, J. Velíšek
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868-874The generation and applications of carbon-sulfur (C-S) bonds in numerous natural and medicinal products have led to the development of efficient techniques for C-S bond creation.
Patel, Dixita J, Chikhalia, Kishor H
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A new polymorph of 1-acetyl-2-thiohydantoin
The crystal structure of a new polymorph of 1-acetyl-2-thiohydantoin has been determined by X-ray diffraction. The crystal, C5H6N2O2S, belongs to space group P1 with cell dimensions of a = 4.9865(7)Å, b = 5.5716(7)Å, c = 12.544(2)Å, a = 74.793(8)°, b ...
藤波, 修平 +12 more
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Experimental and computational study of the energetics of hydantoin and 2-thiohydantoin [PDF]
This work reports an experimental and a theoretical study of two imidazolidine derivatives, hydantoin (CAS No. 461-72-3) and 2-thiohydantoin (CAS No. 503-87-7).
Ana L R Silva +5 more
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Treatment of 5-arylidene-2-thiohydantoin (1a-d) with alkyl bromoacetate and chloroacetic acid gave the esters 2a-f and the acids 2g-j, respectively. 2a was refluxed with concentrated hydrochloric acid to give 5-benzylidene hydantoin. 2 was cyclized with acetic anhydride to give the bicyclic product 3. 5-Arylidene-2-thiohydantoin derivatives (1a, b) and
A. F. A. Shalaby +2 more
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Hydantoins have been known as medicinally active compounds since the 1940s and thiohydantoin derivatives are currently undergoing clinical trials as potent androgen receptor antagonist drugs.
Silversides, Jon D. +3 more
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This study provides a basis for a new and straightforward method for LC/MS/MS-based screening of N-terminal protein adducts. This procedure is denoted the “FIRE procedure” as fluorescein isothiocyanate (FITC) gave superior sensitivity by LC/MS/MS when ...
Per Rydberg +3 more
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Rhodanines are accepted as advantaged heterocycles in medicinal chemistry as one of the 4-thiazolidinones subtypes. The aim of this paper is to analyze the features of rhodanine and its application in pharmacy and medicine.
Seyyed Mojtaba Mousavi +4 more
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Synthesis of Thiohydantoin-Castanospermine Glycomimetics as Glycosidase Inhibitors
The preparation of bicyclic carbohydrate mimics related to (+)-castanospermine incorporating a thiohydantoin moiety is reported. The synthetic approach is compatible with molecular diversity-oriented strategies and involves α-azidoesters, built at the C ...
Matilde Aguilar-Moncayo (2358781) +3 more
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Reactions with 5-Arylazo- and 5-Arylidene-4-thiohydantoin Derivatives
5-Arylazo-3-phenyl-4-thiohydantoins (IIa-g) have been prepared and then treated with primary aromatic amines to afford the corresponding 5-arylazo-4-arylimino-3-phenyl hydantoins (VIIa-c).
M . A. Abd Allah +5 more
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