Results 91 to 100 of about 1,373 (204)
Green Chemistry Letters and Reviews, 2016 A simple and eco-friendly method for the synthesis of novel imidazo[2,1-b][1,3]thiazin derivatives has been developed via the one-pot, three-component and solvent-free reaction of thiohydantoins, aromatic aldehyde and 5,5-dimethylcyclohexane-1,3-dione in
Mohammad Mehdi Ghanbari
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Artificial Cells, Nanomedicine, and Biotechnology, 2019 Rhodanines are accepted as advantaged heterocycles in medicinal chemistry as one of the 4-thiazolidinones subtypes. The aim of this paper is to analyze the features of rhodanine and its application in pharmacy and medicine.
Seyyed Mojtaba Mousavi +4 more
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868-874The generation and applications of carbon-sulfur (C-S) bonds in numerous natural and medicinal products have led to the development of efficient techniques for C-S bond creation.
Patel, Dixita J, Chikhalia, Kishor H
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, 2010 Hydantoins have been known as medicinally active compounds since the 1940s and thiohydantoin derivatives are currently undergoing clinical trials as potent androgen receptor antagonist drugs.
Silversides, Jon D. +3 more
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Experimental and computational study of the energetics of hydantoin and 2-thiohydantoin [PDF]
, 2013 This work reports an experimental and a theoretical study of two imidazolidine derivatives, hydantoin (CAS No. 461-72-3) and 2-thiohydantoin (CAS No. 503-87-7).
Ana L R Silva +5 more
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1H NMR study of interactions between cisplatin and N-allyl-2-thiohydantoin type ligand
, 2018 cis-Diamminedichloridoplatinum(II) or cisplatin, cis-[PtCl2(NH3)2], is the one of most widely used anticancer drug. Its effectiveness against various cancer types is well established.
Živković, Marija +4 more
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Biological potential of new molecular hybrids of thiohydantoin and zingerone derivatives
, 2022 Molecular hybridization is one of the most valuable structure modification tools currently used in drug construction. The concept of hybridization is usually achieved via chemical connection of two or more biologically active pharmacophoric moieties to ...
Virijevic, Katarina +3 more
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مجلة بغداد للعلومRecently, some prostate cancer patients have acquired resistance to the second -generation drugs (anzalutamide and apalutamide) prescribed for the treatment of this disease due to the emergence of the F876L mutation, which represents a challenge
Qusay Hussein Hays +1 more
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Synthesis of Thiohydantoin-Castanospermine Glycomimetics as Glycosidase Inhibitors
, 2016 The preparation of bicyclic carbohydrate mimics related to (+)-castanospermine incorporating a thiohydantoin moiety is reported. The synthetic approach is compatible with molecular diversity-oriented strategies and involves α-azidoesters, built at the C ...
Matilde Aguilar-Moncayo (2358781) +3 more
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, 2004 WOS: 000221424800004PubMed ID: 151099823-substituted-2-thiohydantoin derivatives were synthesized and their Structures elucidated by IR, H-1-NMR spectroscopy and elemental analysis.
Benkli, Kadriye +3 more
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