Results 71 to 80 of about 1,373 (204)

Facile regiodivergent synthesis of spiro pyrrole-substituted pseudothiohydantoins and thiohydantoins via reaction of [e]-fused 1H-pyrrole-2,3-diones with thiourea

Beilstein Journal of Organic Chemistry, 2019
A highly divergent synthesis of regioisomeric thiohydantoins and pseudothiohydantoins spiro-fused to a pharmacologically valuable pyrrole-2-one fragment involving the reaction of [e]-fused 1H-pyrrole-2,3-diones with thioureas was developed.
Aleksandr I. Kobelev, Nikita A. Tretyakov, Ekaterina E. Stepanova, Maksim V. Dmitriev, Michael Rubin, Andrey N. Maslivets   +5 more
doaj   +1 more source

Microwave Assisted Synthesis of Novel Functionalized Hydantoin Derivatives and Their Conversion to 5-(Z) Arylidene-4H-imidazoles

Molecules, 2011
2-(Alkyl-1-yl)-1H-imidazol-5(4H)-ones 5a–n were synthesized via nucleophilic substitution of the methylsulfanyl group of the corresponding 2-(methylthio)-1H-imidazol-5(4H)-ones 3a–c with suitably substituted secondary amines.
Edward R. Biehl, Haribabu Ankati, Sukanta Kamila   +2 more
doaj   +1 more source

Determination of Acid Dissociation Constants (pKa) of Bicyclic Thiohydantoin-Pyrrolidine Compounds in 20% Ethanol-Water Hydroorganic Solvent

International Journal of Analytical Chemistry, 2014
The acid dissociation constants of potential bioactive fused ring thiohydantoin-pyrrolidine compounds were determined by potentiometric titration in 20% (v/v) ethanol-water mixed at 25±0.1°C, at an ionic background of 0.1 mol/L of NaCl using the ...
Yahya Nural, H. Ali Döndaş, Hayati Sarı, Hasan Atabey, Samet Belveren, Müge Gemili   +5 more
doaj   +1 more source

Enobosarm in Muscle Wasting

JCSM Communications, Volume 9, Issue 1, January/June 2026.
Stephan von Haehling
wiley   +1 more source

Investigating the Kinetic Impact of DMSO on Platinum(II) Coordination: An Experimental and Computational Study of Cisplatin and 2-Thiohydantoin Ligands

Inorganics
This study presents a thorough investigation of chemical outcomes during the reaction of cisplatin and 2-thiohydantoin ligands in the presence of DMSO. Aided by NMR spectroscopy and quantum chemical calculations, the influence of DMSO substitution on the
Petar B. Stanić, Amina I. Nurović, Tanja V. Soldatović, Darko P. Ašanin, Marko V. Rodić, Biljana M. Šmit, Goran V. Janjić   +6 more
doaj   +1 more source

Progress on the Chemical Constituents Derived from Glucosinolates in Maca (Lepidium meyenii)

Natural Products and Bioprospecting, 2018
Maca (Lepidium meyenii Walp.), a famous food supplement, has drawn an unprecedented international interest over the last two decades. It was assumed that glucosinolates, macamides, macaenes, and alkaloids are the main bioactive components of Maca before.
Yan-Jie Huang, Xing-Rong Peng, Ming-Hua Qiu   +2 more
doaj   +1 more source

Solution-Phase Synthesis of a Combinatorial Thiohydantoin Library¹

, 2016
An efficient one-pot three-component synthesis of thiohydantoins was developed. In the first step, amino acid esters were alkylated by imine formation with aldehydes and reduction by sodium triacetoxyborohydride.
Mui Mui Sim (3030531), Arasu Ganesan (3040221)   +1 more
core   +2 more sources

Apoptotic Effects of Some Thiohydantoin Derivatives

, 2010
WOS: 000282700000017Objectives: The aim of this study is to investigate the effects of newly synthesized 3-phenly-and 3-(4-methoxyphenyl)-2-thiohydantoin derivatives on 5RP7 ve CO25 cell apoptosis.
Akalın Çiftçi, Gülsen, Seller, Zerrin   +1 more
core  

Synthesis, antimicrobial and anticancer activities of some 2-thiohydantoin derivatives [PDF]

, 2017
641-648The vital organic compound 3-[(2-hydroxy-3-methoxybenzylidene)- amino]-2-thiohydantoin 3 has been prepared via the reaction of 2-hydroxy-3-methoxybenzaldehyde 1 with thiosemicarbazide to give N-[(2-hydroxy-3-methoxybenzylidene) amino]thiourea 2 ...
Abubshait, Samar A
core  

5-(2-Methylsulfanylethyl)-3-prop-2-enyl-2-sulfanylideneimidazolidin-4-one

Molbank
An amino acid-derived 2-thiohydantoin, 5-(2-methylsulfanylethyl)-3-prop-2-enyl-2-sulfanylideneimidazolidin-4-one, obtained from l-methionine, was synthesized in a two-step reaction protocol with allyl isothiocyanate.
Petar Stanić, Marko V. Rodić, Biljana Šmit   +2 more
doaj   +1 more source