Results 61 to 70 of about 1,373 (204)

HYDANTOINS: THE SYNTHESIS OF 2-THIOHYDANTOIN. [SEVENTH PAPER.] [PDF]

Journal of the American Chemical Society, 1911
n ...
Johnson, Treat B., Nicolet, Ben H.
openaire   +1 more source

Chiral Quaternary Ammonium Salt‐Catalyzed Enantioselective Addition Reactions of Hydantoins

Helvetica Chimica Acta, Volume 107, Issue 3, March 2024.
Abstract We herein report a protocol for the asymmetric 1,4‐addition of hydantoins to various Michael acceptors by utilizing Cinchona alkaloid‐based chiral quaternary ammonium salt catalysts. Various products were obtained with moderate to good enantioselectivities and accompanying computational investigations helped to identify key interactions ...
Katharina Röser, Lucas Prameshuber, Sajid Jahangir, Sharath Chandra Mallojjala, Jennifer S. Hirschi, Mario Waser   +5 more
wiley   +1 more source

Dopaminergic neuronal death via necroptosis in Parkinson's disease: A review of the literature

European Journal of Neuroscience, Volume 59, Issue 6, Page 1079-1098, March 2024.
We reviewed the current literature on the potential role of necroptosis, a recently characterized regulated cell death mechanism, in Parkinson's disease (PD) pathogenesis. We summarized findings from studies on necroptosis in PD preclinical models and PD human tissue samples, discussing how manipulating necroptosis might open a novel therapeutic ...
Maria Regoni, Flavia Valtorta, Jenny Sassone   +2 more
wiley   +1 more source

A new polymorph of 1-acetyl-2-thiohydantoin [PDF]

, 2009
The crystal structure of a new polymorph of 1-acetyl-2-thiohydantoin has been determined by X-ray diffraction. The crystal, C5H6N2O2S, belongs to space group P1 with cell dimensions of a = 4.9865(7)Å, b = 5.5716(7)Å, c = 12.544(2)Å, a = 74.793(8)°, b ...
10242538, Fujinami, Shuhei, Kuwae, Akio, 10377400, 国本, 浩喜, Taniguchi, Kazutaka, 911, 10115272, Suda, Mitsuhiro, 藤波, 修平, Maeda, Shiro, Honda, Mitsunori, 60242533, 須田, 光広, 220, 10605, 本田, 光典, 14600, 604, Okumura, Hisako, Hanai, Kazuhiko, 14603, Kunimoto, Ko-Ki, 14604, 14601, 14602   +25 more
core   +1 more source

Fluorous parallel synthesis of a hydantoin/thiohydantoin library [PDF]

Molecular Diversity, 2005
Fluorous tagging strategy is applied to solution-phase parallel synthesis of a library containing hydantoin and thiohydantoin analogs. Two perfluoroalkyl (Rf)-tagged alpha-amino esters each react with six aromatic aldehydes under reductive amination conditions. Twelve amino esters then each react with 10 isocyanates and isothiocyanates in parallel. The
Yimin, Lu, Wei, Zhang
openaire   +2 more sources

Necrostatin‐1 releasing nanoparticles: In vitro and in vivo efficacy for supporting immunoisolated islet transplantation outcomes

Journal of Biomedical Materials Research Part A, Volume 112, Issue 2, Page 288-295, February 2024.
Abstract Immunoisolation of pancreatic islets in alginate microcapsules allows for transplantation in the absence of immunosuppression but graft survival time is still limited. This limited graft survival is caused by a combination of tissue responses to the encapsulating biomaterial and islets. A significant loss of islet cells occurs in the immediate
Alexandra M. Smink, Juan D. Medina, Bart J. de Haan, Andrés J. García, Paul de Vos   +4 more
wiley   +1 more source

Solid-Phase Synthesis of Novel Heterocycles Containing Thiohydantoin and Isoxazole Rings

, 2016
Solid-Phase Synthesis of Novel Heterocycles Containing Thiohydantoin and Isoxazole ...
Mark J. Kurth (1328874), Kyung-Ho Park (770569)   +1 more
core   +1 more source

Synthesis and molecular modeling studies of new thiohydantoin-triazole hybrids as anticancer agents

Journal of Saudi Chemical Society
The targeted thiohydantoin-triazole hybrid compounds 5a-d and 9a-d were synthesized by the copper-catalyzed click reaction of 2-azido-N-arylacetamides 3a-d with the appropriate alkynes, thiohydantoin moiety linked to a propargyl group.
Wael M. Alamoudi
doaj   +1 more source

A comparison of the exposure system of glycidol‐related chemicals on the formation of glycidol‐hemoglobin adducts

Food Science &Nutrition, Volume 12, Issue 1, Page 471-480, January 2024.
The exposure systems of glycidol‐related chemicals on the formation of glycidol‐hemoglobin adducts diHOPrVal were compared. DiHOPrVal formation was observed using several chemicals other than glycidol with different behaviors in vitro and in vivo. However, in both cases, the amount of diHOPrVal produced was very small compared with glycidol. This study
Yuko Shimamura, Yuri Wada, Moeka Tashiro, Hiroshi Honda, Shuichi Masuda   +4 more
wiley   +1 more source

Synthesis and crystal structure of (S)-5-isopropyl-5-methyl-2-thiohydantoin [PDF]

, 2013
(S)-5-Isopropyl-5-methyl-2-thiohydantoin was synthesized by one-pot reaction of α-methyl-L-valine and thiourea in the absence of solvent. The crystal structure of this compound has been determined from single crystal X-ray diffraction data.
Fujinami, Shuhei, Tanaka, Keiko, Ichitani, Masaki, Kuwae, Akio, Kitoh, Soh-ichi, Suda, Mitsuhiro, Honda, Mitsunori, Hanai, Kazuhiko, Kunimoto, Ko-Ki   +8 more
core   +1 more source