Results 61 to 70 of about 873 (170)

5-(2-Methylsulfanylethyl)-3-prop-2-enyl-2-sulfanylideneimidazolidin-4-one

open access: yesMolbank
An amino acid-derived 2-thiohydantoin, 5-(2-methylsulfanylethyl)-3-prop-2-enyl-2-sulfanylideneimidazolidin-4-one, obtained from l-methionine, was synthesized in a two-step reaction protocol with allyl isothiocyanate.
Petar Stanić   +2 more
doaj   +1 more source

Design, synthesis and evaluation of anticancer activity of novel 2-thioxoimidazolidin-4-one derivatives bearing pyrazole, triazole and benzoxazole moieties

open access: yesChemistry Central Journal, 2018
A novel series of substituted 2-thiohydantoin incorporated with benzoimidazole, pyrazole, triazole and/or benzoxazole moieties has been synthesized using (E)-3-[1-(4-bromophenyl)ethylideneamino]-2-thioxoimidazolidin-4-one 1 as the key starting material ...
Heba A. Elhady   +2 more
doaj   +1 more source

Organic-salt-mediated highly regioselective N3-alkylation of 2-thiophenytoin via Michael reaction under solvent-free conditions

open access: yesGreen Chemistry Letters and Reviews, 2016
A regioselective N3-alkylation of 5,5-diphenyl-2-thiohydantoin (2-thiophenytoin) using a very efficient mild base K2CO3 and α,β-unsaturated esters in the presence of organic salt TBAB (tetrabutylammonium bromide) at room temperature has been reported (3b–
Gholamhassan Imanzadeh   +2 more
doaj   +1 more source

Advances in Chemistry of Isothiocyanate-derived Colourants

open access: yesCzech Journal of Food Sciences, 2009
This study is focused on the reactions of isothiocyanates (ITCs) in the presence of amino compounds leading to coloured structures via substituted 2-thiohydantoins.
K. Cejpek, J. Velíšek
doaj   +1 more source

LC/MS/MS Analysis of N-Terminal Protein Adducts with Improved Sensitivity: A Comparison of Selected Edman Isothiocyanate Reagents

open access: yesInternational Journal of Analytical Chemistry, 2009
This study provides a basis for a new and straightforward method for LC/MS/MS-based screening of N-terminal protein adducts. This procedure is denoted the “FIRE procedure” as fluorescein isothiocyanate (FITC) gave superior sensitivity by LC/MS/MS when ...
Per Rydberg   +3 more
doaj   +1 more source

A FLUORIMETRIC ASSAY FOR MINUTE AMOUNTS OF SOME THIOHYDANTOINS

open access: yesJournal of Pharmacy and Pharmacology, 1958
Abstract A fluorimetric assay sensitive to μg. quantities of certain thiohydantoins has been devised using dichloroquinone chloroimide as a fluorescence reagent. The nature of the buffer used is critical. Satisfactory results have been obtained for recoveries from urine, spinal fluid and plasma.
M E, AUERBACH, E, ANGELL
openaire   +2 more sources

An efficient synthesis of imidazo[2,1-b][1,3]thiazins via a one-pot, three-component and solvent-free reaction

open access: yesGreen Chemistry Letters and Reviews, 2016
A simple and eco-friendly method for the synthesis of novel imidazo[2,1-b][1,3]thiazin derivatives has been developed via the one-pot, three-component and solvent-free reaction of thiohydantoins, aromatic aldehyde and 5,5-dimethylcyclohexane-1,3-dione in
Mohammad Mehdi Ghanbari
doaj   +1 more source

A conceptual review of rhodanine: current applications of antiviral drugs, anticancer and antimicrobial activities

open access: yesArtificial Cells, Nanomedicine, and Biotechnology, 2019
Rhodanines are accepted as advantaged heterocycles in medicinal chemistry as one of the 4-thiazolidinones subtypes. The aim of this paper is to analyze the features of rhodanine and its application in pharmacy and medicine.
Seyyed Mojtaba Mousavi   +4 more
doaj   +1 more source

Study of the Anticancer and Antimicrobial Biological Activity of a New Series of Thiohydantoin Derivatives

open access: yesمجلة بغداد للعلوم
        Recently, some prostate cancer patients have acquired resistance to the second -generation drugs (anzalutamide and apalutamide) prescribed for the treatment of this disease due to the emergence of the F876L mutation, which represents a challenge
Qusay Hussein Hays   +1 more
doaj   +1 more source

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