Results 71 to 80 of about 2,082 (147)

Determination of Acid Dissociation Constants (pKa) of Bicyclic Thiohydantoin-Pyrrolidine Compounds in 20% Ethanol-Water Hydroorganic Solvent

International Journal of Analytical Chemistry, 2014
The acid dissociation constants of potential bioactive fused ring thiohydantoin-pyrrolidine compounds were determined by potentiometric titration in 20% (v/v) ethanol-water mixed at 25±0.1°C, at an ionic background of 0.1 mol/L of NaCl using the ...
Yahya Nural, H. Ali Döndaş, Hayati Sarı, Hasan Atabey, Samet Belveren, Müge Gemili   +5 more
doaj   +1 more source

Enobosarm in Muscle Wasting

JCSM Communications, Volume 9, Issue 1, January/June 2026.
Stephan von Haehling
wiley   +1 more source

Progress on the Chemical Constituents Derived from Glucosinolates in Maca (Lepidium meyenii)

Natural Products and Bioprospecting, 2018
Maca (Lepidium meyenii Walp.), a famous food supplement, has drawn an unprecedented international interest over the last two decades. It was assumed that glucosinolates, macamides, macaenes, and alkaloids are the main bioactive components of Maca before.
Yan-Jie Huang, Xing-Rong Peng, Ming-Hua Qiu   +2 more
doaj   +1 more source

Glikoenzim-inhibítorok előállítása = Synthesis of glycoenzyme inhibitors [PDF]

, 2008
A szénhidrát alapú gyógyszerek kifejlesztésének egyik iránya a glikoenzimek gátlószereinek és szerkezet?hatás összefüggéseiknek (SAR) felderítése. A kutatás során glikozidázokat, amilázokat és glikogén foszforilázokat (GP) gátló cukorszármazékokat ...
Czifrák, Katalin, Györgydeák, Zoltán, Hadady, Zsuzsa, Nagy, Veronika, Somsák, László, Vágvölgyiné dr.Tóth, Marietta   +5 more
core  

Sinteza i biološko djelovanje novih 1-benzil i 1-benzoil 3-heterocikličkih derivata indola [PDF]

, 2010
Starting from 1-benzyl- (2a) and 1-benzoyl-3-bromoacetyl indoles (2b) new heterocyclic, 2-thioxoimidazolidine (4a,b), imidazolidine-2,4-dione (5a,b), pyrano(2,3-d)imidazole (8a,b and 9a,b), 2-substituted quinoxaline (11a,b–17a,b) and triazolo(4,3-a ...
A. Barry, A. Kar, A. Mandour, A. Mndzhoyan, E. El-Sawy, E. Szymanska, Eslam El-Sawy, Fatma Bassyouni, Hanaa Rady, J. Dickstein, J. Okuda, J. William, K. Bodendorf, M. Radwan, Mohamed Abdlla, R. Cao, R. Tiwari, S. Kotharkar, S. Martin, S. Sondhi, Sherifa Abu-Bakr, T. Mosmann, W. Qinjie, W. Reeve   +23 more
core   +2 more sources

Sturgeon osteocalcin shares structural features with matrix gla protein evolutionary relationship and functional implications [PDF]

, 2013
Osteocalcin (OC) and matrix Gla protein (MGP) are considered evolutionarily related because they share key structural features, although they have been described to exert different functions.
Beck, Bendtsen, Blom, Boskey, Cancela, Cancela, Carla S.B. Viegas, Conceição, Conceição, Cranenburg, Dina C. Simes, Fraser, Gundberg, Hale, Hall, Hashimoto, Hauschka, Hauschka, Hinoi, Hosoda, Hur, Karsenty, Krieger, Laizé, Laizé, Lian, Luo, M. Leonor Cancela, Matthew K. Williamson, Murshed, Ortiz-Delgado, Otawara, Oury, Paul A. Price, Pinto, Price, Price, Price, Price, Proudfoot, Rice, Schurgers, Schurgers, Seidah, Shanahan, Shearer, Simes, Simes, Sofia Cavaco, Thomas, Thomas, Viegas, Viegas, Viegas, Viegas, Vincent Laizé, Wallace, Yagami   +57 more
core   +1 more source

Synthesis and molecular modeling studies of new thiohydantoin-triazole hybrids as anticancer agents

Journal of Saudi Chemical Society
The targeted thiohydantoin-triazole hybrid compounds 5a-d and 9a-d were synthesized by the copper-catalyzed click reaction of 2-azido-N-arylacetamides 3a-d with the appropriate alkynes, thiohydantoin moiety linked to a propargyl group.
Wael M. Alamoudi
doaj   +1 more source

α-Amylase inhibitors : a review of raw material and isolated compounds from plant source [PDF]

, 2012
Inhibition of α-amylase, enzyme that plays a role in digestion of starch and glycogen, is considered a strategy for the treatment of disorders in carbohydrate uptake, such as diabetes and obesity, as well as, dental caries and periodontal diseases ...
Batista, Pérola de Oliveira Magalhães Dias, Sales, Paloma Michelle de, Silveira, Dâmaris, Simeoni, Luiz Alberto, Souza, Paula Monteiro de   +4 more
core   +2 more sources

Design, synthesis and evaluation of anticancer activity of novel 2-thioxoimidazolidin-4-one derivatives bearing pyrazole, triazole and benzoxazole moieties

Chemistry Central Journal, 2018
A novel series of substituted 2-thiohydantoin incorporated with benzoimidazole, pyrazole, triazole and/or benzoxazole moieties has been synthesized using (E)-3-[1-(4-bromophenyl)ethylideneamino]-2-thioxoimidazolidin-4-one 1 as the key starting material ...
Heba A. Elhady, Refat El-Sayed, Hamedah S. Al-nathali   +2 more
doaj   +1 more source

5-(2-Methylsulfanylethyl)-3-prop-2-enyl-2-sulfanylideneimidazolidin-4-one

Molbank
An amino acid-derived 2-thiohydantoin, 5-(2-methylsulfanylethyl)-3-prop-2-enyl-2-sulfanylideneimidazolidin-4-one, obtained from l-methionine, was synthesized in a two-step reaction protocol with allyl isothiocyanate.
Petar Stanić, Marko V. Rodić, Biljana Šmit   +2 more
doaj   +1 more source