Results 81 to 90 of about 2,082 (147)
Synthesis, biological activity and electron impact of mass spectra of trisubstituted-2-thiohydantoins [PDF]
3-[1-(2-Hydroxyphenyl)ethylideneamino]-2-thiohydantoin (2) was prepared via cyclization of 2-hydroxyacetophenone thiosemicarbazone (1) with ethyl chloroacetate in the presence of fused sodium acetate. The chemical behaviour of 2 towards acetic anhydride,
Abd El-Meniem, Mohamad +2 more
core
Role of necroptosis in the pathogenesis of solid organ injury [PDF]
, 2015 Necroptosis is a type of regulated cell death dependent on the activity of receptor-interacting serine/threonine-protein (RIP) kinases. However, unlike apoptosis, it is caspase independent.
Eguchi, S +5 more
core +1 more source
Green Chemistry Letters and Reviews, 2016 A regioselective N3-alkylation of 5,5-diphenyl-2-thiohydantoin (2-thiophenytoin) using a very efficient mild base K2CO3 and α,β-unsaturated esters in the presence of organic salt TBAB (tetrabutylammonium bromide) at room temperature has been reported (3b–
Gholamhassan Imanzadeh +2 more
doaj +1 more source
Solvent effects on the structure-property relationship of anticonvulsant hydantoin derivatives: A solvatochromic analysis [PDF]
, 2011 Considering the pharmaceutical importance of hydantoins, a set of 25 derivatives of phenytoin, nirvanol and 5-methyl-5-phenylhydantoin, the lipophilicities of which were gradually increased by the introduction of different alkyl, cycloalkyl and alkenyl ...
Gordana Ušćumlić +2 more
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Advances in Chemistry of Isothiocyanate-derived Colourants
Czech Journal of Food Sciences, 2009 This study is focused on the reactions of isothiocyanates (ITCs) in the presence of amino compounds leading to coloured structures via substituted 2-thiohydantoins.
K. Cejpek, J. Velíšek
doaj +1 more source
Synthetic, enzyme kinetic, and protein crystallographic studies of C-[béta]-D-glucopyranosyl pyrroles and imidazoles reveal and explain low nanomolar inhibition of human liver glycogen phosphorylase [PDF]
, 2016 LBK
Batta, Gyula +11 more
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Sibiriline, a new small chemical inhibitor of receptor-interacting protein kinase 1, prevents immune-dependent hepatitis [PDF]
, 2017 Necroptosis is a regulated form of cell death involved in several disease models including in particular liver diseases. Receptor-interacting protein kinases, RIPK1 and RIPK3, are the main serine/threonine kinases driving this cell death pathway.
Afonso +47 more
core +5 more sources
International Journal of Analytical Chemistry, 2009 This study provides a basis for a new and straightforward method for LC/MS/MS-based screening of N-terminal protein adducts. This procedure is denoted the “FIRE procedure” as fluorescein isothiocyanate (FITC) gave superior sensitivity by LC/MS/MS when ...
Per Rydberg +3 more
doaj +1 more source
Artificial Cells, Nanomedicine, and Biotechnology, 2019 Rhodanines are accepted as advantaged heterocycles in medicinal chemistry as one of the 4-thiazolidinones subtypes. The aim of this paper is to analyze the features of rhodanine and its application in pharmacy and medicine.
Seyyed Mojtaba Mousavi +4 more
doaj +1 more source
1,3-Dipolar cycloadditions of azomethine imines [PDF]
, 2015 Azomethine imines are considered 1,3-dipoles of the aza-allyl type which are transient intermediates and should be generated in situ but can also be stable and isolable compounds.
Nájera, Carmen +2 more
core +3 more sources