Results 1 to 10 of about 156,491 (330)
TLR2 variants and Helicobacter pylori: revisiting a controversial link [PDF]
Upsala Journal of Medical SciencesObjective: Although polymorphisms in the Toll-like receptor 2 (TLR2) gene have been proposed as host genetic factors influencing susceptibility to Helicobacter pylori infection, existing data remain inconclusive.
Duygu Kirkik +2 more
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Сучасна педіатрія: Україна, 2022 Атопічний дерматит являє собою хронічне рецидивне запальне захворювання шкіри, яке уражує 5-20% дітей. Повітряні алергени, що походять із кліщів домашнього пилу, можуть викликати атопічний дерматит.
O.V. Mozyrska
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The role of Toll-like receptors in chemoradiotherapy-induced gastrointestinal mucositis
口腔疾病防治, 2021 Mucositis is a common gastrointestinal complication in cancer patients undergoing chemoradiotherapy, including oral mucositis and gastrointestinal mucositis, with clinical manifestations of oral ulcers, vomiting, diarrhea and pain that seriously reduce ...
JI Ling +3 more
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Effect of Lipopolysaccharide from Rhodobacter sphaeroides on Inflammatory Pathway and Oxidative Stress in Renal Ischemia/Reperfusion Injury in Male Rats [PDF]
Archives of Razi Institute, 2021 Ischemia/reperfusion injury (IRI) is caused by a sudden temporary impairment of the blood flow to the particular organ. The IRI of the kidneys is one of the main causes of acute kidney injury.
M Aal-Aaboda, A. R Abu Raghif, N. R Hadi
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Pifu-xingbing zhenliaoxue zazhi, 2023 Objective To investigate the effect of G12R mutation in Cx26 on the expression of TLR2 and its downstream inflammatory factors in human keratinocytes.
Zhaoying LIU, Yankun LU, Han MA
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Targeting TLR2 for Vaccine Development [PDF]
Journal of Immunology Research, 2014 Novel and more effective immunization strategies against many animal diseases may profit from the current knowledge on the modulation of specific immunity through stimulation of innate immune receptors. Toll-like receptor (TLR)2-targeting formulations, such as synthetic lipopeptides and antigens expressed in fusion with lipoproteins, have been shown to
Afonso P. Basto, Alexandre Leitão
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TLR2 Looks at Lipoproteins [PDF]
Immunity, 2009 Toll-like receptors (TLRs) have evolved to recognize lipoproteins from diverse species of bacteria. In this issue of Immunity, Kang et al. (2009) provide insight into the mechanisms by which TLR2-TLR6 heterodimers recognize diacylated liporoteins, whereas TLR2-TLR1 heterodimers recognize triacylated lipopeptides.
Schenk, Mirjam +2 more
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Sialylation of TLR2 initiates osteoclast fusion [PDF]
Bone Research, 2022 AbstractThe molecular control of osteoclast formation is still not clearly elucidated. Here, we show that a process of cell recognition mediated by Siglec15-TLR2 binding is indispensable and occurs prior to cell fusion in RANKL-mediated osteoclastogenesis. Siglec15 has been shown to regulate osteoclastic bone resorption.
Ce Dou +5 more
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Generation of anti-TLR2 intrabody mediating inhibition of macrophage surface TLR2 expression and TLR2-driven cell activation [PDF]
BMC Biotechnology, 2010 AbstractBackgroundToll-like receptor (TLR) 2 is a component of the innate immune system and senses specific pathogen associated molecular patterns (PAMPs) of both microbial and viral origin. Cell activation via TLR2 and other pattern recognition receptors (PRRs) contributes to sepsis pathology and chronic inflammation both relying on overamplification ...
Kirschning, Carsten Jürgen +9 more
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TLR2 & Co: a critical analysis of the complex interactions between TLR2 and coreceptors [PDF]
Journal of Leukocyte Biology, 2013 ABSTRACTTLRs play a major role in microbe-host interactions and innate immunity. Of the 10 functional TLRs described in humans, TLR2 is unique in its requirement to form heterodimers with TLR1 or TLR6 for the initiation of signaling and cellular activation.
Bergenhenegouwen, J. van +7 more
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