Results 1 to 10 of about 132,938 (232)
Extracts of Feijoa Inhibit Toll-Like Receptor 2 Signaling and Activate Autophagy Implicating a Role in Dietary Control of IBD [PDF]
, 2015 Inflammatory bowel disease (IBD) is a heterogeneous chronic inflammatory disease affecting the gut with limited treatment success for its sufferers.
A Asea +39 more
core +28 more sources
SARS-CoV-2 spike protein induces inflammation via TLR2-dependent activation of the NF-κB pathway
eLife, 2021 The pathogenesis of COVID-19 is associated with a hyperinflammatory response; however, the precise mechanism of SARS-CoV-2-induced inflammation is poorly understood. Here, we investigated direct inflammatory functions of major structural proteins of SARS-
Shahanshah Khan +5 more
semanticscholar +2 more sources
TLR2 senses the SARS-CoV-2 envelope protein to produce inflammatory cytokines
Nature Immunology, 2021 The innate immune response is critical for recognizing and controlling infections through the release of cytokines and chemokines. However, severe pathology during some infections, including SARS-CoV-2, is driven by hyperactive cytokine release, or a ...
Min Zheng +7 more
semanticscholar +1 more source
Сучасна педіатрія: Україна, 2022 Атопічний дерматит являє собою хронічне рецидивне запальне захворювання шкіри, яке уражує 5-20% дітей. Повітряні алергени, що походять із кліщів домашнього пилу, можуть викликати атопічний дерматит.
O.V. Mozyrska
doaj +1 more source
Effect of Lipopolysaccharide from Rhodobacter sphaeroides on Inflammatory Pathway and Oxidative Stress in Renal Ischemia/Reperfusion Injury in Male Rats [PDF]
Archives of Razi Institute, 2021 Ischemia/reperfusion injury (IRI) is caused by a sudden temporary impairment of the blood flow to the particular organ. The IRI of the kidneys is one of the main causes of acute kidney injury.
M Aal-Aaboda, A. R Abu Raghif, N. R Hadi
doaj +1 more source
Cell Death and Differentiation, 2021 During cancer therapy, phagocytic clearance of dead cells plays a vital role in immune homeostasis. The nonapoptotic form of cell death, ferroptosis, exhibits extraordinary potential in tumor treatment.
Xiang Luo +12 more
semanticscholar +1 more source
The role of Toll-like receptors in chemoradiotherapy-induced gastrointestinal mucositis
口腔疾病防治, 2021 Mucositis is a common gastrointestinal complication in cancer patients undergoing chemoradiotherapy, including oral mucositis and gastrointestinal mucositis, with clinical manifestations of oral ulcers, vomiting, diarrhea and pain that seriously reduce ...
JI Ling +3 more
doaj +1 more source
Nature Communications, 2021 Pathways to control the spreading of α-synuclein (α-syn) and associated neuropathology in Parkinson’s disease (PD), multiple system atrophy (MSA) and dementia with Lewy bodies (DLB) are unclear.
Debashis Dutta +5 more
semanticscholar +1 more source
Pifu-xingbing zhenliaoxue zazhi, 2023 Objective To investigate the effect of G12R mutation in Cx26 on the expression of TLR2 and its downstream inflammatory factors in human keratinocytes.
Zhaoying LIU, Yankun LU, Han MA
doaj +1 more source
A. Muciniphila Suppresses Colorectal Tumorigenesis by Inducing TLR2/NLRP3-Mediated M1-Like TAMs
Cancer immunology research, 2021 The authors show that A. muciniphila can induce M1-like macrophages through a TLR2/NF-κB/NLRP3 pathway to suppress colorectal cancer progression, suggesting a new potential therapeutic strategy for colorectal cancer prevention and treatment.
Lina Fan +11 more
semanticscholar +1 more source