Results 11 to 20 of about 133,056 (344)
Phloretin as a Potent Natural TLR2/1 Inhibitor Suppresses TLR2-Induced Inflammation [PDF]
Nutrients, 2018 Toll-like receptor 2 (TLR2) responses are involved in various inflammatory immune disorders. Phloretin is a naturally occurring dietary flavonoid that is abundant in fruit.
Jieun Kim +6 more
semanticscholar +4 more sources
The Role of TLR2, TLR4, and TLR9 in the Pathogenesis of Atherosclerosis [PDF]
International Journal of Inflammation, 2016 Toll-like receptors (TLRs) are key players in the pathogenesis of inflammatory conditions including coronary arterial disease (CAD). They are expressed by a variety of immune cells where they recognize pathogen-associated molecular patterns (PAMPs). TLRs
Mohsin H. K. Roshan, Amos Tambo, N. Pace
semanticscholar +6 more sources
Biology, 2022 Simple Summary Due to the broad functions of Toll-like receptor 2 (TLR2) in innate immunity, the drive for the development of TLR2-targeted therapeutic treatments has accelerated in recent decades.
Wanbin Hu, H. Spaink
semanticscholar +1 more source
TLR2 Looks at Lipoproteins [PDF]
Immunity, 2009 Toll-like receptors (TLRs) have evolved to recognize lipoproteins from diverse species of bacteria. In this issue of Immunity, Kang et al. (2009) provide insight into the mechanisms by which TLR2-TLR6 heterodimers recognize diacylated liporoteins, whereas TLR2-TLR1 heterodimers recognize triacylated lipopeptides.
Robert L. Modlin +3 more
openaire +3 more sources
Журнал микробиологии, эпидемиологии и иммунобиологии, 2022 The aim of the work was to evaluate the diagnostic value of TLR2 and TLR4 expression on periodontal and peripheral blood lymphoid cells by immunofluorescence microscopy in patients with chronic periodontitis associated with key periodontal pathogenic ...
Viktor N. Tsarev +5 more
doaj +1 more source
TLR2 and TLR4 in Parkinson’s disease pathogenesis: the environment takes a toll on the gut
Translational Neurodegeneration, 2021 Parkinson’s disease (PD) is an incurable, devastating disorder that is characterized by pathological protein aggregation and neurodegeneration in the substantia nigra. In recent years, growing evidence has implicated the gut environment and the gut-brain
A. Gorecki +2 more
semanticscholar +1 more source
TLR2 is expressed on activated T cells as a costimulatory receptor [PDF]
Proceedings of the National Academy of Sciences, 2004 Toll is the founder of a group of pattern recognition receptors that play a critical role in the innate immunity in Drosophila . At least 10 distinct Toll-like receptors (TLRs), recognizing pathogen-associated molecular patterns, have now been identified in humans.
Mousa Komai‐Koma +4 more
openalex +6 more sources
TLR2 & Co: a critical analysis of the complex interactions between TLR2 and coreceptors [PDF]
Journal of Leukocyte Biology, 2013 ABSTRACTTLRs play a major role in microbe-host interactions and innate immunity. Of the 10 functional TLRs described in humans, TLR2 is unique in its requirement to form heterodimers with TLR1 or TLR6 for the initiation of signaling and cellular activation.
Bergenhenegouwen, J. van +7 more
openaire +5 more sources
Bioinformatic analysis of differentially expressed genes in porcine intestinal epithelial cells infected with transmissible gastroenteritis virus [PDF]
Kafkas Universitesi Veteriner Fakültesi Dergisi, 2021 Transmissible Gastroenteritis Virus (TGEV) infection is one of the leading causes of diarrhea in piglets. Intestinal immune system plays an important role in maintaining the intestinal mucosa"s integrity and resisting infection by pathogens. However, the
Xu-xuan ZHANG +7 more
doaj +1 more source
Endothelial TLR2 promotes proangiogenic immune cell recruitment and tumor angiogenesis
Science Signaling, 2021 Toll-like receptor 2 contributes to innate immune responses in endothelial cells as well as in immune cells. A shared Toll for innate immunity Toll-like receptor 2 (TLR2) is found in various tissues but is best known for its role in the innate immune ...
Michael G. McCoy +7 more
semanticscholar +1 more source