Results 31 to 40 of about 101,572 (275)

Prognostic role of TLR4 and TLR2 in hepatocellular carcinoma [PDF]

open access: yesActa Oncologica, 2021
Hepatocellular carcinoma (HCC) is the second most common cause of cancer mortality [1]. The overall 5-year survival of HCC is only 8%; with curative surgery, the survival rate increases up to 40% [...
Huhta Heikki   +5 more
openaire   +4 more sources

Hyperexpression of TLR2 and TLR4 in patients with ischemic stroke in acute period of the disease

open access: yesМедицинская иммунология, 2020
Pathogenesis of ischemic stroke  is actively  involved  in the  system  of innate immunity. Under conditions of cerebral  ischemia, a number of biologically  active  substances are  released  that  interact with innate immunity receptors, in particular ...
L. V. Gankovskaya   +7 more
doaj   +1 more source

The association of rs4696480 polymorphism in TLR2 gene and Staphylococcus aureus skin colonization in children with atopic dermatitis

open access: yesУкраїнський журнал Перинатологія і педіатрія, 2022
Topicality. Up to 90% of patients with atopic dermatitis are colonized with S. aureus, with S. aureus predominance being unique to atopic dermatitis. TLR2 play a role in the presentation of S. aureus antigens in a course of atopic dermatits. Purpose -
O.V. Mozyrska
doaj   +1 more source

EXPRESSION FEATURES OF TOLL-LIKE RECEPTOR 2 AND TOLL-LIKE RECEPTOR 4 IN CHILDREN WITH ASTHMA

open access: yesМедицинская иммунология, 2017
Currently actively  discussed  the  role  of innate immunity receptors, in particular TLRs  in the immunopathogenesis of bronchial asthma (BA).The aim of our work was to study the expression of ТLR2 and TLR4 on the nasal mucosal cells and peripheral ...
L. V. Gankovskaya   +7 more
doaj   +1 more source

Activation of Ca2+-Dependent Signaling by TLR2 [PDF]

open access: yesThe Journal of Immunology, 2006
Abstract Upon contact with airway epithelial cells, bacterial products activate Ca2+ fluxes that are required for induction of NF-κB-dependent gene expression. TLR2 is apically displayed on airway cells, making it a likely transducer linking bacterial stimuli and kinases that affect Ca2+ release. Using biochemical and genetic approaches,
Jarin Chun, Alice Prince
openaire   +2 more sources

Toll-Like Receptor (TLR) 1, 2, and 6 Gene Polymorphisms Support Evidence of Innate Immune Factors in Schizophrenia

open access: yesNeuropsychiatric Disease and Treatment, 2023
Carlo E Sotelo-Ramírez,1,2 Beatriz Camarena,2 Marco Antonio Sanabrais-Jiménez,2 Julio Uriel Zaragoza-Hoyos,2 Bruno Ordoñez-Martínez,2 Raul I Escamilla-Orozco,3 Beatriz Gómez-González4 1Posgrado en Biología Experimental, Universidad Autónoma Metropolitana-
Sotelo-Ramírez CE   +6 more
doaj  

High Expression of TLR2 in the serum of patients with tuberculosis and lung cancer, and can promote the progression of lung cancer

open access: yesMathematical Biosciences and Engineering, 2020
PurposeThe present paper investigated the expression of TLR2 in serum of patients with pulmonary tuberculosis and lung cancer, and verifiedthe effect of TLR2 on the biological characteristics of lung cancer cells.
Ming Zhang, Yingying Zhou, Yanli Zhang
doaj   +1 more source

Hemagglutinin protein of Peste des Petits Ruminants virus (PPRV) activates the innate immune response via Toll-like receptor 2 signaling

open access: yesVirulence, 2021
The toll-like receptor (TLR) family comprises both cell-surface and intracellular receptors that recognize different types of pathogen-associated molecular patterns (PAMPs) leading to the production of pro-inflammatory cytokines and subsequent ...
José M. Rojas   +7 more
doaj   +1 more source

TLR2 Mediates Immunity to Experimental Cysticercosis [PDF]

open access: yesInternational Journal of Biological Sciences, 2011
Information concerning TLR-mediated antigen recognition and regulation of immune responses during helminth infections is scarce. TLR2 is a key molecule required for innate immunity and is involved in the recognition of a wide range of viruses, bacteria, fungi and parasites. Here, we evaluated the role of TLR2 in a Taenia crassiceps cysticercosis model.
Yadira Ledesma-Soto   +4 more
openaire   +2 more sources

Trypanosoma evansi evades host innate immunity by releasing extracellular vesicles to activate TLR2-AKT signaling pathway

open access: yesVirulence, 2021
Surra, one of the most important animal diseases with economic consequences in Asia and South America, is caused by Trypanosoma evansi. However, the mechanism of immune evasion by T. evansi has not been extensively studied.
Ran Wei   +7 more
doaj   +1 more source

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