Results 41 to 50 of about 151,127 (263)

Toll-like receptor (TLR) 2 and TLR4 gene expression in canine heart [PDF]

open access: yes, 2007
Toll-like receptors (TLRs) are archetypal pattern recognition receptors of immediate importance for an efficacious innate immune response. TLRs exhibit marked differential tissue activity and their levels within a discrete cell type can be highly dynamic.
Blecha, Frank   +2 more
core   +2 more sources

Toll-Like Receptor (TLR) 1, 2, and 6 Gene Polymorphisms Support Evidence of Innate Immune Factors in Schizophrenia

open access: yesNeuropsychiatric Disease and Treatment, 2023
Carlo E Sotelo-Ramírez,1,2 Beatriz Camarena,2 Marco Antonio Sanabrais-Jiménez,2 Julio Uriel Zaragoza-Hoyos,2 Bruno Ordoñez-Martínez,2 Raul I Escamilla-Orozco,3 Beatriz Gómez-González4 1Posgrado en Biología Experimental, Universidad Autónoma Metropolitana-
Sotelo-Ramírez CE   +6 more
doaj  

Trypanosoma evansi evades host innate immunity by releasing extracellular vesicles to activate TLR2-AKT signaling pathway

open access: yesVirulence, 2021
Surra, one of the most important animal diseases with economic consequences in Asia and South America, is caused by Trypanosoma evansi. However, the mechanism of immune evasion by T. evansi has not been extensively studied.
Ran Wei   +7 more
doaj   +1 more source

Increased Expression of Toll-Like Receptor (TLR) 2 and TLR6 on Peripheral Blood Monocytes by Induction of Staphylococcal Enterotoxin B During Exacerbation of Atopic Dermatitis Patients

open access: yesClinical, Cosmetic and Investigational Dermatology, 2023
Fitria Salim,1,2 Hendra Gunawan,3 Oki Suwarsa,3 Endang Sutedja3 1Doctoral Study Program, Faculty of Medicine, Universitas Padjadjaran, Bandung, West Java, Indonesia; 2Department of Dermatology and Venereology, Faculty of Medicine, Universitas Syiah Kuala,
Salim F, Gunawan H, Suwarsa O, Sutedja E
doaj  

A Review: The Significance of Toll-Like Receptors 2 and 4, and NF-κB Signaling in Endothelial Cells during Atherosclerosis

open access: yesFrontiers in Bioscience-Landmark
Atherosclerosis (AS) is a chronic inflammatory vascular disease that begins with endothelial activation followed by a series of inflammatory responses, plaque formation, and finally rupture.
Baoxin Yan   +10 more
doaj   +1 more source

Insights on adaptive and innate immunity in canine leishmaniosis [PDF]

open access: yes, 2016
Canine leishmaniosis (CanL) is caused by the parasite Leishmania infantum and is a systemic disease, which can present with variable clinical signs, and clinicopathological abnormalities.
Abi Abdallah   +19 more
core   +4 more sources

Ketogenic Diet as an Epigenetic Therapy in SETD1B‐Related Epilepsy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Histone lysine methyltransferases such as SETD1B regulate chromatin structure and gene transcription. Ketone bodies, including butyrate, act as histone deacetylase inhibitors. We report a 4‐year‐old boy with SETD1B‐related absence epilepsy, refractory to conventional medications, who achieved sustained > 90% seizure reduction on the Modified ...
Erica Tsang   +10 more
wiley   +1 more source

Argon Alleviates Bone Cancer Pain by Mitigating Neuronal Ferroptosis via the TLR2-COX-2 Pathway

open access: yesFrontiers in Bioscience-Landmark
Background: Bone cancer pain (BCP) related neuronal damage is associated with ferroptosis, a regulated cell death dependent on iron. The noble gas argon is known to have neuroprotective effects, reducing neuroinflammation and enhancing
Peipei Kang   +9 more
doaj   +1 more source

Microbiological Aspects and Immunity Response of Bacteria Causing Pulpitis [PDF]

open access: yes, 2011
The oral cavity is a very widely distributed ecosystem in which several hundred microbial species normally cohabit harmoniously. Under special conditions some microorganisms with potential are promoted, leading to inflammation & infection by ...
Deepak Dwivedi   +2 more
core   +2 more sources

Controlling 3D Contractility via Engineered Fibrous Hydrogel Composites

open access: yesAdvanced Functional Materials, EarlyView.
A tunable composite contractile assembly (CCA) is developed that can permit or resist contraction without changing cell‐adhesion and density, unlike collagen whose inherent coupling of these ECM cues limits its use as a platform in contractility studies.
Karen L. Xu   +7 more
wiley   +1 more source

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