Results 11 to 20 of about 845 (125)
Gene-Set Enrichment Analysis for Identifying Genes and Biological Activities Associated with Growth Traits in Dromedaries [PDF]
Animals, 2022 Growth is an important heritable economic trait for dromedaries and necessary for planning a successful breeding program. Until now, genome-wide association studies (GWAS) and QTL-mapping have identified significant single nucleotide polymorphisms (SNPs)
Morteza Bitaraf Sani +8 more
doaj +5 more sources
Ecotoxicology and Environmental SafetyEthylene thiourea (ETU), a metabolite of the fungicide ethylene bisdithiocarbamate (EBDC), has received great concern because of its harmful effects. ETU-induced anorectal malformations (ARMs) in rat models have been reported and widely used in the study
Peiqi Liu +7 more
doaj +2 more sources
Tmod3 participates in platelet formation and sizing in mouse fetal liver (278.9)
FASEB Journal, 2014 Tropomodulins (Tmod) bind tropomyosin and cap the pointed ends of actin filaments. Tmod3 is the only Tmod isoform detected in human and mouse platelets. To study its function in platelets we have examined platelets from Tmod3 ‐/‐
Diane Krause
exaly +2 more sources
Tropomodulin’s Actin-Binding Abilities Are Required to Modulate Dendrite Development [PDF]
Frontiers in Molecular Neuroscience, 2018 There are many unanswered questions about the roles of the actin pointed end capping and actin nucleation by tropomodulins (Tmod) in regulating neural morphology.
Kevin T. Gray +13 more
doaj +4 more sources
Role of Tropomodulins in brain physiology and pathology
Neurobiology of DiseaseActin dynamics are crucial for the morphogenesis and function of neurons in the brain. Tropomodulins (Tmods) belong to a family of actin-binding proteins that cap the pointed-end of actin filaments. There are four Tmod isoforms, and three of which, Tmod1,
Chuan Hong +6 more
doaj +2 more sources
Heterozygous Tropomodulin 3 mice have improved lung vascularization after chronic hypoxia. [PDF]
Hum Mol Genet, 2022 The molecular mechanisms leading to high-altitude pulmonary hypertension (HAPH) remains poorly understood. We previously analyzed the whole genome sequence of Kyrgyz highland population and identified eight genomic intervals having a potential role in ...
Stobdan T +5 more
europepmc +2 more sources
Advances in Cancer Biology - Metastasis, 2021 Background: Oral cancer is one of the highly aggravated conditions of oral pathologies. The commonly diagnosed form of oral cancer is oral squamous cell carcinoma (OSCC).
Sapna Khowal +4 more
doaj +1 more source
MiR-145 modulates the radiosensitivity of non-small cell lung cancer cells by suppression of TMOD3
Carcinogenesis, 2021 AbstractRadioresistance is a major problem encountered in the treatment of non-small cell lung cancer (NSCLC). Aberrant microRNA (miRNA) expression contributes to multiple cancer-associated signaling pathways and profoundly influences effects of radiotherapy (RT) in cancers.
Hang Li +5 more
openaire +2 more sources