Results 31 to 40 of about 807 (128)

Additional file 1 of Cleavage of tropomodulin-3 by asparagine endopeptidase promotes cancer malignancy by actin remodeling and SND1/RhoA signaling [PDF]

, 2022
Additional file 1: Fig. S1. Relationship between AEP, Tmod3 and lysosome. (A) Representative images showing lysosomal status of A172 and U87-MG cells treated with shCtrl or shAEP (left panel) with quantification (right panel). Scale bar, 100 μm.
Keman Liao (11611105), Yongming Qiu (171424), Yingying Lin (1790404), Binghong Chen (11080383), Zhonggang Shi (12972190), Qi Lv (169217), Yan Lin (285018), Wenrui Zhang (1486636), Chunhui Ma (668361), Junjun Qiu (10462250), Jiazhou Ye (5712152), Zhongrun Qian (11645269), Rong Liang (587636), Mengying Wang (4443901)   +13 more
core   +1 more source

Identification of tumor antigens and immune subtypes of pancreatic adenocarcinoma for mRNA vaccine development

Molecular Cancer, 2021
Background Although mRNA vaccines have been effective against multiple cancers, their efficacy against pancreatic adenocarcinoma (PAAD) remains undefined.
Xing Huang, Gang Zhang, Tianyu Tang, Tingbo Liang   +3 more
doaj   +1 more source

Additional file 13 of Cleavage of tropomodulin-3 by asparagine endopeptidase promotes cancer malignancy by actin remodeling and SND1/RhoA signaling [PDF]

, 2022
Additional file 13: Supplementary Table 3.
Keman Liao (11611105), Yongming Qiu (171424), Yingying Lin (1790404), Binghong Chen (11080383), Zhonggang Shi (12972190), Qi Lv (169217), Yan Lin (285018), Wenrui Zhang (1486636), Chunhui Ma (668361), Junjun Qiu (10462250), Jiazhou Ye (5712152), Zhongrun Qian (11645269), Rong Liang (587636), Mengying Wang (4443901)   +13 more
core   +1 more source

Additional file 7 of Cleavage of tropomodulin-3 by asparagine endopeptidase promotes cancer malignancy by actin remodeling and SND1/RhoA signaling [PDF]

, 2022
Additional file 7: Fig. S7. AEP promotes GBM progression by cleaving Tmod3 in vitro and in vivo. (A) CCK-8 assays of U87-MG and A172 cells with NC, AEP KD, AEP KD/tTmod3-N res, AEP KD/tTmod3-C res and AEP KD/tTmod3-N res/tTmod3-C res.
Keman Liao (11611105), Yongming Qiu (171424), Yingying Lin (1790404), Binghong Chen (11080383), Zhonggang Shi (12972190), Qi Lv (169217), Yan Lin (285018), Wenrui Zhang (1486636), Chunhui Ma (668361), Junjun Qiu (10462250), Jiazhou Ye (5712152), Zhongrun Qian (11645269), Rong Liang (587636), Mengying Wang (4443901)   +13 more
core   +1 more source

Proteomic Screening for Cellular Targets of the Duck Enteritis Virus Protein VP26 Reveals That the Host Actin-Myosin II Network Regulates the Proliferation of the Virus. [PDF]

Int J Mol Sci
Duck enteritis virus (DEV) is responsible for duck viral enteritis, a contagious and lethal disease in waterfowls. The host proteins targeted by DEV are unknown.
Chen L, Zhu YC, Yun T, Ye WC, Ni Z, Hua JG, Zhang C.   +6 more
europepmc   +2 more sources

Advances in the discovery of genetic elements underlying longissimus dorsi muscle growth and development in the pig

Animal Genetics, Volume 54, Issue 6, Page 709-720, December 2023., 2023
AbstractAs a major source of protein in human diets, pig meat plays a crucial role in ensuring global food security. Key determinants of meat production refer to the chemical and physical compositions or characteristics of muscle fibers, such as the number, hypertrophy potential, fiber‐type conversion and intramuscular fat deposition.
Qingjie Zeng, Zhi‐Qiang Du
wiley   +1 more source

Additional file 9 of Cleavage of tropomodulin-3 by asparagine endopeptidase promotes cancer malignancy by actin remodeling and SND1/RhoA signaling [PDF]

, 2022
Additional file 9: Fig. S9.Rescue of truncations of Tmod3 has limited effects on lysosomes in GBM cells.Representative images showing lysosomal status of indicated U87-MG and A172 cells (left panel) with quantification (right panel).
Keman Liao (11611105), Yongming Qiu (171424), Yingying Lin (1790404), Binghong Chen (11080383), Zhonggang Shi (12972190), Qi Lv (169217), Yan Lin (285018), Wenrui Zhang (1486636), Chunhui Ma (668361), Junjun Qiu (10462250), Jiazhou Ye (5712152), Zhongrun Qian (11645269), Rong Liang (587636), Mengying Wang (4443901)   +13 more
core   +1 more source

PSMC4 promotes prostate carcinoma progression by regulating the CBX3–EGFR‐PI3K‐AKT‐mTOR pathway

Journal of Cellular and Molecular Medicine, Volume 27, Issue 16, Page 2437-2447, August 2023., 2023
Abstract Proteasome 26S subunit ATPase 4 (PSMC4) could regulate cancer progression. However, the function of PSMC4 in prostate carcinoma (PCa) progression requires further clarification. In the study, PSMC4 and chromobox 3 (CBX3) levels were verified by TCGA data and tissue microarrays.
Kaifeng Liu, Shengmin Zhang, Yongzhan Gong, Panyan Zhu, Weigan Shen, Qi Zhang   +5 more
wiley   +1 more source

Single‐cell transcriptomic analysis of oral masticatory and lining mucosa‐derived mesenchymal stromal cells

Journal of Clinical Periodontology, Volume 50, Issue 6, Page 807-818, June 2023., 2023
Abstract Aim To reveal the heterogeneity of ex vivo‐cultured human mesenchymal stromal cells derived from either masticatory or lining oral mucosa. Materials and Methods Cells were retrieved from the lamina propria of the hard palate and alveolar mucosa of three individuals. The analysis of transcriptomic‐level differences was accomplished using single‐
Ilan Pinkhasov, Liron Kabakov, Carlos E. Nemcovsky, Miron Weinreb, Pnina Schlesinger, Omer Bender, Maayan Gal, Daniel Z. Bar, Evgeny Weinberg   +8 more
wiley   +1 more source

A Pilot Analysis of Genome‐Wide DNA Methylation Patterns in Mouse Cartilage Reveals Overlapping Epigenetic Signatures of Aging and Osteoarthritis

ACR Open Rheumatology, Volume 4, Issue 12, Page 1004-1012, December 2022., 2022
Objective Cartilage epigenetic changes are strongly associated with human osteoarthritis (OA). However, the influence of individual environmental OA risk factors on these epigenetic patterns has not been determined; herein we characterize cartilage DNA methylation patterns associated with aging and OA in a mouse model. Methods Murine knee cartilage DNA
Vladislav Izda, Christopher M. Dunn, Emmaline Prinz, Leoni Schlupp, Emily Nguyen, Cassandra Sturdy, Matlock A. Jeffries   +6 more
wiley   +1 more source