Results 31 to 40 of about 845 (125)

Single‐cell transcriptomic analysis of oral masticatory and lining mucosa‐derived mesenchymal stromal cells

Journal of Clinical Periodontology, Volume 50, Issue 6, Page 807-818, June 2023., 2023
Abstract Aim To reveal the heterogeneity of ex vivo‐cultured human mesenchymal stromal cells derived from either masticatory or lining oral mucosa. Materials and Methods Cells were retrieved from the lamina propria of the hard palate and alveolar mucosa of three individuals. The analysis of transcriptomic‐level differences was accomplished using single‐
Ilan Pinkhasov, Liron Kabakov, Carlos E. Nemcovsky, Miron Weinreb, Pnina Schlesinger, Omer Bender, Maayan Gal, Daniel Z. Bar, Evgeny Weinberg   +8 more
wiley   +1 more source

A Pilot Analysis of Genome‐Wide DNA Methylation Patterns in Mouse Cartilage Reveals Overlapping Epigenetic Signatures of Aging and Osteoarthritis

ACR Open Rheumatology, Volume 4, Issue 12, Page 1004-1012, December 2022., 2022
Objective Cartilage epigenetic changes are strongly associated with human osteoarthritis (OA). However, the influence of individual environmental OA risk factors on these epigenetic patterns has not been determined; herein we characterize cartilage DNA methylation patterns associated with aging and OA in a mouse model. Methods Murine knee cartilage DNA
Vladislav Izda, Christopher M. Dunn, Emmaline Prinz, Leoni Schlupp, Emily Nguyen, Cassandra Sturdy, Matlock A. Jeffries   +6 more
wiley   +1 more source

Structural and molecular characterization of paraventricular thalamic glucokinase‐expressing neuronal circuits in the mouse

Journal of Comparative Neurology, Volume 530, Issue 11, Page 1773-1949, August 2022., 2022
By using a genetically modified mouse model and viral tracing approaches, we mapped both the anterograde and the retrograde projections of a subpopulation of neurons in the anterior paraventricular thalamic nucleus, molecularly defined by the expression of glucokinase (GckaPVT).
Sevasti Gaspari, Simon Quenneville, Ana Rodriguez Sanchez‐Archidona, Bernard Thorens, Sophie Croizier   +4 more
wiley   +1 more source

Additional file 3 of Cleavage of tropomodulin-3 by asparagine endopeptidase promotes cancer malignancy by actin remodeling and SND1/RhoA signaling

, 2022
Additional file 3: Fig. S3. Tmod3 is highly expressed in many solid tumors and associated with poor prognosis. (A) The relative expression of TMOD3 in cholangiocarcinoma(CHOL), pancreatic adenocarcinoma (PAAD)and stomach adenocarcinoma(STAD) compared to ...
Keman Liao (11611105), Yongming Qiu (171424), Yingying Lin (1790404), Binghong Chen (11080383), Zhonggang Shi (12972190), Qi Lv (169217), Yan Lin (285018), Wenrui Zhang (1486636), Chunhui Ma (668361), Junjun Qiu (10462250), Jiazhou Ye (5712152), Zhongrun Qian (11645269), Rong Liang (587636), Mengying Wang (4443901)   +13 more
core   +1 more source

A gene network of uterine luminal epithelium organizes mouse blastocyst implantation

Reproductive Medicine and Biology, Volume 21, Issue 1, January/December 2022., 2022
Abstract Purpose The receptive endometrium is critical for blastocyst implantation. In mice, after blastocysts enter the uterine cavities on day 4 of pregnancy (day 1 = vaginal plug), blastocyst attachment is completed within 24 h, accompanied by dynamic interactions between the uterine luminal epithelium and the blastocysts.
Shizu Aikawa, Yasushi Hirota, Yamato Fukui, Chihiro Ishizawa, Rei IIda, Tetsuaki Kaku, Tomoyuki Hirata, Shun Akaeda, Takehiro Hiraoka, Mitsunori Matsuo, Yutaka Osuga   +10 more
wiley   +1 more source

Additional file 6 of Cleavage of tropomodulin-3 by asparagine endopeptidase promotes cancer malignancy by actin remodeling and SND1/RhoA signaling

, 2022
Additional file 6: Fig. S6. The truncated Tmod3 produced by AEP promote GBM proliferation and invasion. (A) CCK-8 assays of U87-MG and A172 cells with or without truncations of Tmod3 overexpression. (B) Representative images showing IHC staining of Tmod3,
Keman Liao (11611105), Yongming Qiu (171424), Yingying Lin (1790404), Binghong Chen (11080383), Zhonggang Shi (12972190), Qi Lv (169217), Yan Lin (285018), Wenrui Zhang (1486636), Chunhui Ma (668361), Junjun Qiu (10462250), Jiazhou Ye (5712152), Zhongrun Qian (11645269), Rong Liang (587636), Mengying Wang (4443901)   +13 more
core   +1 more source

Additional file 1 of Cleavage of tropomodulin-3 by asparagine endopeptidase promotes cancer malignancy by actin remodeling and SND1/RhoA signaling

, 2022
Additional file 1: Fig. S1. Relationship between AEP, Tmod3 and lysosome. (A) Representative images showing lysosomal status of A172 and U87-MG cells treated with shCtrl or shAEP (left panel) with quantification (right panel). Scale bar, 100 μm.
Keman Liao (11611105), Yongming Qiu (171424), Yingying Lin (1790404), Binghong Chen (11080383), Zhonggang Shi (12972190), Qi Lv (169217), Yan Lin (285018), Wenrui Zhang (1486636), Chunhui Ma (668361), Junjun Qiu (10462250), Jiazhou Ye (5712152), Zhongrun Qian (11645269), Rong Liang (587636), Mengying Wang (4443901)   +13 more
core   +1 more source

The Role of Tropomodulin's Actin and Tropomyosin Binding Sites in Dendritic Morphology [PDF]

, 2016
Neurons are morphologically complicated cells. In order to develop their immensely intricate shape, neurons coordinate the function of many structural proteins, such as actin.
Gray, Kevin
core   +4 more sources

Additional file 13 of Cleavage of tropomodulin-3 by asparagine endopeptidase promotes cancer malignancy by actin remodeling and SND1/RhoA signaling

, 2022
Additional file 13: Supplementary Table 3.
Keman Liao (11611105), Yongming Qiu (171424), Yingying Lin (1790404), Binghong Chen (11080383), Zhonggang Shi (12972190), Qi Lv (169217), Yan Lin (285018), Wenrui Zhang (1486636), Chunhui Ma (668361), Junjun Qiu (10462250), Jiazhou Ye (5712152), Zhongrun Qian (11645269), Rong Liang (587636), Mengying Wang (4443901)   +13 more
core   +1 more source

MOLECULAR MECHANISMS OF ISOFORM-DEPENDENT INTERACTIONS OF PROTEINS FROM THE TROPOMODULIN FAMILY WITH THEIR BINDING PARTNERS [PDF]

, 2016
Actin filaments are major components of the cytoskeleton in eukaryotic cells and are involved in vital cellular functions such as cell motility and muscle contraction.
Colpan, Mert
core   +4 more sources