Results 21 to 30 of about 233,587 (310)

Toll-like receptor 2 and Toll-like receptor 4 predict favorable prognosis in local pancreatic cancer

Tumor Biology, 2018
Toll-like receptors play an essential role in our innate immune system and are a focus of interest in contemporary cancer research. Thus far, Toll-like receptors have shown promising prognostic value in carcinomas of the oral cavity, colon, and ovaries ...
Mira A Lanki, Hanna E Seppänen, Harri K Mustonen, Camilla Böckelman, Anne T Juuti, Jaana K Hagström, Caj H Haglund   +6 more
doaj   +1 more source

Coactivation of TLR2 and TLR8 in Primary Human Monocytes Triggers a Distinct Inflammatory Signaling Response

Frontiers in Physiology, 2018
Innate immune signaling is essential to mount a fast and specific immune response to pathogens. Monocytes and macrophages are essential cells in the early response in their capacity as ubiquitous phagocytic cells.
Korbinian Bösl, Miriam Giambelluca, Markus Haug, Markus Haug, Marit Bugge, Terje Espevik, Richard K. Kandasamy, Richard K. Kandasamy, Bjarte Bergstrøm, Bjarte Bergstrøm   +9 more
doaj   +1 more source

Hyperreactivity of Blood Leukocytes in Patients with NAFLD to Ex Vivo Lipopolysaccharide Treatment Is Modulated by Metformin and Phosphatidylcholine but Not by Alpha Ketoglutarate. [PDF]

PLoS ONE, 2015
Toll-like receptor 4 and proinflammatory cytokines play a central role in the progression of nonalcoholic fatty liver disease. We investigated IL-1, IL-6 and TNFα production and toll-like receptor 4 in both--obese and lean patients with non-alcoholic ...
Agnieszka Zwolak, Agnieszka Szuster-Ciesielska, Jadwiga Daniluk, Olga Słabczyńska, Martyna Kandefer-Szerszeń   +4 more
doaj   +1 more source

Toll-like receptors in COPD [PDF]

European Respiratory Journal, 2017
TLR4 and NODs could be potential therapeutic targets in chronic obstructive pulmonary diseasehttp://ow.ly ...
Hansbro, Philip M., Haw, Tatt Jhong, Starkey, Malcolm R., Miyake, Kensuke   +3 more
openaire   +3 more sources

Regulatory T cells isolated from endometriotic peritoneal fluid express a different number of Toll-like receptors

Einstein (São Paulo), 2020
Objective To analyze and compare the expression of Toll-like receptors by regulatory T cells present in the peritoneal fluid of patients with and without endometriosis.
Camila Hernandes, Bárbara Yasmin Gueuvoghlanian-Silva, Vitor Ulisses Monnaka, Natalia Mazini Ribeiro, Welbert de Oliveira Pereira, Sérgio Podgaec   +5 more
doaj   +2 more sources

Toll‐like receptor 9 signaling in chronic lymphocytic leukemia cell lines

FEBS Open Bio, 2023
Chronic lymphocytic leukemia (CLL) is a prototypic neoplasia in which malignant cells strongly depend on microenvironmental stimulations in the lymphoid tissues where they accumulate; leukemic cells are exposed to interaction with bystander and accessory
Miriam Meloni, Ilenia Sana, Maria Elena Mantione, Michela Riba, Marta Muzio   +4 more
doaj   +1 more source

TOLL-LIKE RECEPTORS (TLR) 2 AND 4 EXPRESSION OF KERATINOCYTES FROM PATIENTS WITH LOCALIZED AND DISSEMINATED DERMATOPHYTOSIS

Revista do Instituto de Medicina Tropical de São Paulo, 2015
There are few studies on the role of innate immune response in dermatophytosis. An investigation was conducted to define the involvement of Toll-Like Receptors (TLRs) 2 and 4 in localized (LD) and
Cristiane Beatriz de Oliveira, Cídia Vasconcellos, Neusa Y. Sakai-Valente, Mirian Nacagami Sotto, Fernanda Guedes Luiz, Walter Belda JÚNIOR, Maria da Gloria Teixeira de Sousa, Gil Benard, Paulo Ricardo Criado   +8 more
doaj   +1 more source

Toll-like Receptors and the Eye [PDF]

Investigative Opthalmology & Visual Science, 2006
The immune response to microbial pathogens relies on both innate and adaptive components.1 The innate or immediate response is mediated in large measure by leukocytes of the blood, such as neutrophils (PMNs) and macrophages, cells that phagocytose and kill the pathogens and that concurrently coordinate additional host responses by synthesis of a wide ...
Linda D. Hazlett, Fushin X Yu
openaire   +3 more sources

Decreased Toll-like Receptor (TLR) 2 and 4 Expression in Spermatozoa in Couples with Unexplained Recurrent Spontaneous Abortion (URSA)

Iranian Journal of Allergy, Asthma and Immunology, 2019
Studies have shown that toll-like receptors (TLRs) play some important roles in reproductive processes such as ovulation, spermatogenesis, sperm capacitation, fertilization, and pregnancy to the best of our knowledge, no study has evaluated the ...
Nasrin Sereshki, Alireza Andalib, Ataollah Ghahiri, Ferdos Mehrabian, Roya Sherkat, Abbas Rezaei   +5 more
doaj   +1 more source

Toll-like receptors as adjuvant receptors

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 2002
The mammalian Toll-like receptors (TLRs) are expressed on macrophages and dendritic cells, which are primarily involved in innate immunity. At present, ligands for several of the TLRs, such as TLR2, TLR3, TLR4, TLR5, TLR6, and TLR9, have been identified.
Shizuo Akira, Tsuneyasu Kaisho
openaire   +3 more sources