Results 31 to 40 of about 34,084,722 (297)
Corrigendum – Targeting Toll-Like Receptor 4: a promising strategy to prevent type 1 diabetes occurrence or recurrence [PDF]
CellR4, 2022 Corrigendum
M. Alibashe-Ahmed +3 more
doaj +1 more source
Tumor Biology, 2017 High mobility group box 1 and toll-like receptor 4/myeloid differentiation factor 88 signaling pathway have been indicated to have oncogenic effects in many cancers.
Yanqiu Yue +8 more
doaj +1 more source
Journal of Genetic Engineering and Biotechnology, 2022 Background Durian (Durio zibethinus L.) is a tropical fruit crop which is popular in Southeast Asia but recently gaining popularity in other parts of the world. In this study, we analyzed the resistance gene analogs (RGAs) of durian through mining of the
Cris Q. Cortaga +3 more
doaj +1 more source
BAFF costimulation of Toll‐like receptor‐activatedB‐1 cells [PDF]
European Journal of Immunology, 2006 AbstractB cell‐activating factor belonging to the TNF family (BAFF) and its receptor BAFF‐R play critical roles in the maturation and survival of conventional peripheral B cells. However, they appeared to be dispensable for the generation and maintenance of CD5+ B‐1 cells as BAFF–/– and BAFF‐R–/– mice have normal B‐1 cell populations.
Lai Guan, Ng +7 more
openaire +2 more sources
Effects of adenovirus-mediated knockdown of IRAK4 on synovitis in the osteoarthritis rabbit model
Arthritis Research & Therapy, 2021 Background The use of interleukin-1 receptor-associated kinase 4 (IRAK4) inhibitor as a treatment for the inflammatory joint disease is a promising method. However, its underlying mechanism in osteoarthritis (OA) remains unclear.
Muzhe Li +5 more
doaj +1 more source
Toll-Like Receptors Gene Polymorphisms in Autoimmune Disease
Frontiers in Immunology, 2021 Toll-like receptors (TLRs) are important initiators of the immune response, both innate and acquired. Evidence suggests that gene polymorphisms within TLRs cause malfunctions of certain key TLR-related signaling pathways, which subsequently increases the
Yingchi Zhang +4 more
doaj +1 more source
Fibronectin III 13-14 Domains Induce Joint Damage via Toll-Like Receptor 4 Activation and Synergize with Interleukin-1 and Tumour Necrosis Factor [PDF]
, 2011 Cartilage loss is a feature of chronic arthritis. It results from degradation of the extracellular matrix which is composed predominantly of aggrecan and type II collagen.
Saralili Dipa Robertson +6 more
core +1 more source
Homology Modeling of Toll-Like Receptor Ligand-Binding Domains [PDF]
, 2010 Toll-like receptors (TLRs) are in the front-line during the initiation of an innate immune response against invading pathogens. TLRs are type I transmembrane proteins that are expressed on the surface of immune system cells.
Wei, Tiandi
core +1 more source
Nature Communications, 2023 The opportunistic fungal pathogen Cryptococcus neoformans causes lethal infections in immunocompromised patients. Macrophages are central to the host response to cryptococci; however, it is unclear how C.
Chinaemerem U. Onyishi +10 more
doaj +1 more source
Colony-stimulating factor-1 suppresses responses to CpG DNA and expression of toll-like receptor 9 but enhances responses to lipopolysaccharide in murine macrophages [PDF]
, 2002 During bacterial infections, the balance between resolution of infection and development of sepsis is dependent upon the macrophage response to bacterial products.
Sweet, Matthew J +15 more
core +1 more source