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Toll-like receptors and toll-like receptor-targeted immunotherapy against glioma [PDF]
Journal of Hematology & Oncology, 2021 Glioma represents a fast proliferating and highly invasive brain tumor which is resistant to current therapies and invariably recurs. Despite some advancements in anti-glioma therapies, patients’ prognosis remains poor.
Yang Xun +3 more
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Türk Yoğun Bakim Derneği Dergisi, 2012 Toll-like receptors (TLR) are a class of proteins that play a key role during the first step of interaction between the pathogens and innate immune system.
Aycan Kundakcı, Arash Pirat
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Toll‐like receptors in mammalian sperm [PDF]
Reproductive Medicine and BiologyBackground Toll‐like receptors (TLRs) are critical components of the innate immune system and are expressed in various cells, including the reproductive system. Although their roles in female reproductive tissues such as the ovaries and uterus, including
Takashi Umehara +2 more
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Toll‐like receptors in health and disease [PDF]
MedCommToll‐like receptors (TLRs) are inflammatory triggers and belong to a family of pattern recognition receptors (PRRs) that are central to the regulation of host protective adaptive immune responses. Activation of TLRs in innate immune myeloid cells directs
Kunyu Wang +4 more
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Toll-like receptors and integrins crosstalk [PDF]
Frontiers in ImmunologyImmune system recognizes invading microbes at both pathogen and antigen levels. Toll-like receptors (TLRs) play a key role in the first-line defense against pathogens. Major functions of TLRs include cytokine and chemokine production.
Fahd Alhamdan +8 more
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Brucella infection and Toll-like receptors [PDF]
Frontiers in Cellular and Infection MicrobiologyBrucella consists of gram-negative bacteria that have the ability to invade and replicate in professional and non-professional phagocytes, and its prolonged persistence in the host leads to brucellosis, a serious zoonosis.
Hui Yu +4 more
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Current Biology, 2011 SummaryBeginning with the physical barrier presented by the epithelium, infectious agents such as viruses and bacteria encounter an array of cellular and molecular countermeasures that evolved within the host to resist them. Host immune responses are of two types, termed innate and adaptive.
Moresco, Eva Marie Y. +2 more
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Immunomodulatory responses of toll like receptors against 2019nCoV
Russian Open Medical Journal, 2021 The present review discusses the immune signals via toll like receptors (TLRs) against 2019nCoV. We researched using different database, up to June 18th, 2020. All the included articles were published in English language. The outcome of this review, that
Amany Sayed Maghraby
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Ocular surface toll like receptors in ageing
BMC Ophthalmology, 2022 Background To evaluate changes in Toll Like Receptors (TLRs) expression at the ocular surface of healthy volunteers within different age groups. Methods Fifty-one healthy volunteers were enrolled in a pilot observational study.
Antonio Di Zazzo +5 more
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Einstein (São Paulo), 2020 Objective To analyze and compare the expression of Toll-like receptors by regulatory T cells present in the peritoneal fluid of patients with and without endometriosis.
Camila Hernandes +5 more
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