Results 1 to 10 of about 119,102 (41)
Emerging role of endosomal toll-like receptors in rheumatoid arthritis [PDF]
, 2014 Toll-like receptors (TLRs) and their downstream signaling pathways have been comprehensively characterized in innate immunity. In addition to this function, these receptors have also been suggested to be involved in the pathogenesis of many autoimmune ...
Chamberlain, Giselle +2 more
core +10 more sources
, 2021 Toll-like receptors (TLRs) are pattern recognition receptors that allow innate immunity to protect our body against invading pathogens. They are alsoregulators of adaptive immunity.
core +1 more source
Interaction between Cannabinoid System and Toll-Like Receptors Controls Inflammation [PDF]
, 2016 Since the discovery of the endocannabinoid system consisting of cannabinoid receptors, endogenous ligands, and biosynthetic and metabolizing enzymes, interest has been renewed in investigating the promise of cannabinoids as therapeutic agents.
McCoy, Kathleen L.
core +7 more sources
Intracellular Toll-like Receptors [PDF]
, 2010 Foreign nucleic acids, the signature of invading viruses and certain bacteria, are sensed intracellularly. The nucleic acid-specific Toll-like receptors (TLRs) detect and signal within endolysosomal compartments, triggering the induction of cytokines ...
Beutler, Bruce, Blasius, Amanda L.
core +1 more source
Transcriptome Modifications in Porcine Adipocytes via Toll-Like Receptors Activation [PDF]
, 2019 Adipocytes are the most important cell type in adipose tissue playing key roles in immunometabolism. We previously reported that nine members of the Toll-like receptor (TLR) family are expressed in an originally established porcine intramuscular pre ...
Albarracín, Leonardo Miguel +13 more
core +1 more source
, 2008 A new emerging paradigm of Uncertain Risk of Suspicion, Threat and Danger, observed across the field of information security, is described. Based on this paradigm a novel approach to anomaly detection is presented.
Aickelin, Uwe, Feyereisl, Jan
core +3 more sources
Identification of single nucleotide polymorphisms in Toll-like receptor candidate genes associated with tuberculosis infection in water buffalo (Bubalus bubalis) [PDF]
, 2014 Toll-like receptors play a key role in innate immunity by recognizing pathogens and activating appropriate responses. Pathogens express several signal molecules (pathogen-associated molecular patterns, PAMPs) essential for survival and pathogenicity ...
Acutis, Pier Luigi +11 more
core +1 more source
Up-regulation of Toll-like receptors 2, 3 and 4 in allergic rhinitis [PDF]
, 2005 BACKGROUND: Toll-like receptors enable the host to recognize a large number of pathogen-associated molecular patterns such as bacterial lipopolysaccharide, viral RNA, CpG-containing DNA and flagellin.
A Muir +31 more
core +3 more sources
Vaccinia virus protein A46R targets multiple Toll-like-interleukin-1 receptor adaptors and contributes to virulence [PDF]
, 2005 Viral immune evasion strategies target key aspects of the host antiviral response. Recently, it has been recognized that Toll-like receptors (TLRs) have a role in innate defense against viruses.
Bartlett, Nathan W +8 more
core +2 more sources
Microbiome-gut-brain axis and toll-like receptors in parkinson\u2019s disease [PDF]
, 2018 Parkinson’s disease (PD) is a progressively debilitating neurodegenerative disease characterized by α-synucleinopathy, which involves all districts of the brain-gut axis, including the central, autonomic and enteric nervous systems.
Caputi, Valentina, Giron, Maria Cecilia
core +2 more sources