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Toll‐like receptors in health and disease [PDF]

open access: yesMedComm
Toll‐like receptors (TLRs) are inflammatory triggers and belong to a family of pattern recognition receptors (PRRs) that are central to the regulation of host protective adaptive immune responses. Activation of TLRs in innate immune myeloid cells directs
Kunyu Wang   +4 more
doaj   +2 more sources

Toll-like receptors and integrins crosstalk [PDF]

open access: yesFrontiers in Immunology
Immune system recognizes invading microbes at both pathogen and antigen levels. Toll-like receptors (TLRs) play a key role in the first-line defense against pathogens. Major functions of TLRs include cytokine and chemokine production.
Fahd Alhamdan   +8 more
doaj   +2 more sources

Brucella infection and Toll-like receptors [PDF]

open access: yesFrontiers in Cellular and Infection Microbiology
Brucella consists of gram-negative bacteria that have the ability to invade and replicate in professional and non-professional phagocytes, and its prolonged persistence in the host leads to brucellosis, a serious zoonosis.
Hui Yu   +4 more
doaj   +2 more sources

Immunomodulatory responses of toll like receptors against 2019nCoV

open access: yesRussian Open Medical Journal, 2021
The present review discusses the immune signals via toll like receptors (TLRs) against 2019nCoV. We researched using different database, up to June 18th, 2020. All the included articles were published in English language. The outcome of this review, that
Amany Sayed Maghraby
doaj   +1 more source

Ocular surface toll like receptors in ageing

open access: yesBMC Ophthalmology, 2022
Background To evaluate changes in Toll Like Receptors (TLRs) expression at the ocular surface of healthy volunteers within different age groups. Methods Fifty-one healthy volunteers were enrolled in a pilot observational study.
Antonio Di Zazzo   +5 more
doaj   +1 more source

Toll-like receptors in cardiac hypertrophy

open access: yesFrontiers in Cardiovascular Medicine, 2023
Toll-like receptors (TLRs) are a family of pattern recognition receptors (PRRs) that can identify pathogen-associated molecular patterns (PAMPs) and damage-associated molecular patterns (DAMPs).
Yanan Zhang   +23 more
doaj   +1 more source

Regulatory T cells isolated from endometriotic peritoneal fluid express a different number of Toll-like receptors

open access: yesEinstein (São Paulo), 2020
Objective To analyze and compare the expression of Toll-like receptors by regulatory T cells present in the peritoneal fluid of patients with and without endometriosis.
Camila Hernandes   +5 more
doaj   +2 more sources

Toll-like receptors and toll-like receptor-targeted immunotherapy against glioma

open access: yesJournal of Hematology & Oncology, 2021
Glioma represents a fast proliferating and highly invasive brain tumor which is resistant to current therapies and invariably recurs. Despite some advancements in anti-glioma therapies, patients’ prognosis remains poor.
Yang Xun   +3 more
doaj   +1 more source

Toll-Like Receptors

open access: yesTürk Yoğun Bakim Derneği Dergisi, 2012
Toll-like receptors (TLR) are a class of proteins that play a key role during the first step of interaction between the pathogens and innate immune system.
Aycan Kundakcı, Arash Pirat
doaj   +1 more source

Toll-like Receptors in Viral Encephalitis

open access: yesViruses, 2021
Viral encephalitis is a rare but serious syndrome. In addition to DNA-encoded herpes viruses, such as herpes simplex virus and varicella zoster virus, RNA-encoded viruses from the families of Flaviviridae, Rhabdoviridae and Paramyxoviridae are important ...
Olivia Luise Gern   +6 more
doaj   +1 more source

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