Virus Recognition by Toll-7 Activates Antiviral Autophagy in Drosophila [PDF]
, 2012 SummaryInnate immunity is highly conserved and relies on pattern recognition receptors (PRRs) such as Toll-like receptors (identified through their homology to Drosophila Toll) for pathogen recognition.
Bambina, Shelly +7 more
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Immunity, Inflammation and Heart Failure: Their Role on Cardiac Function and Iron Status [PDF]
, 2019 Aims: Heart failure is a clinical syndrome characterized by subclinical systemic inflammation and immune system activation associated with iron deficiency.
Corrao S. +10 more
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Activation of toll-like receptors and inflammasome complexes in the diabetic cardiomyopathy-associated inflammation [PDF]
, 2014 Diabetic cardiomyopathy is defined as a ventricular dysfunction initiated by alterations in cardiac energy substrates in the absence of coronary artery disease and hypertension.
Egido, Jesús +4 more
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Role of lipid microdomains in TLR-mediated signalling. [PDF]
, 2015 This is the accepted manuscript. The final version is available at http://www.sciencedirect.com/science/article/pii/S0005273615000930.Over the last twenty years, evidence has been provided that the plasma membrane is partitioned with microdomains ...
Lonez, Caroline, Ruysschaert, Jean-Marie
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Central pathways causing fatigue in neuro-inflammatory and autoimmune illnesses [PDF]
, 2015 The genesis of severe fatigue and disability in people following acute pathogen invasion involves the activation of Toll-like receptors followed by the upregulation of proinflammatory cytokines and the activation of microglia and astrocytes.
Berk, Michael +3 more
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Human mast cell activation through Fc receptors and Toll-like receptors [PDF]
, 2004 Mast cells express high-affinity IgE receptors (FcεRI) on their surface and can be activated to secrete a variety of biologically active mediators by cross-linking of receptor-bound IgE.
Kagaya, Shinji +7 more
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Molecular mechanisms of autoimmunity triggered by microbial infection [PDF]
, 2005 Autoimmunity can be triggered by microbial infection. In this context, the discovery of Toll-like receptors (TLRs) provides new insights and research perspectives.
Anders, Hans-Joachim +3 more
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Toll-like receptor 2 and Toll-like receptor 4 predict favorable prognosis in local pancreatic cancer [PDF]
, 2018 Toll-like receptors play an essential role in our innate immune system and are a focus of interest in contemporary cancer research. Thus far, Toll-like receptors have shown promising prognostic value in carcinomas of the oral cavity, colon, and ovaries ...
Böckelman, Camilla +6 more
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Sublethal infection of C57BL/6 mice with Salmonella enterica serovar typhimurium leads to an increase in levels of toll-like receptor 1 (TLR1), TLR2, and TLR9 mRNA as well as a decrease in levels of TLR6 mRNA in infected organs [PDF]
, 2005 Sublethal infection of C57BL/6 mice with Salmonella enterica serovar Typhimurium M525P initiates a strong inflammatory response. We measured organ expression of mRNA for Toll-like receptors and their associated signaling molecules during S.
Bryant, Clare E +3 more
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Toll-like receptors in domestic animals [PDF]
, 2018 Toll-like receptors are pattern recognition receptors with which hosts recognize pathogen-associated molecular patterns (PAMP). This recognition process is translated rapidly into a meaningful defense reaction.
Burgener, Iwan +3 more
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