The Role of Toll Like Receptors in Hematopoietic Malignancies [PDF]
Frontiers in Immunology, 2016 Toll-like receptors (TLRs) are a family of pattern recognition receptors (PRRs) that shape the innate immune system by identifying pathogen-associated molecular patterns (PAMPS) and host-derived damage associated molecular patterns (DAMPS).
Darlene Monlish +2 more
doaj +4 more sources
, 2008 A new emerging paradigm of Uncertain Risk of Suspicion, Threat and Danger, observed across the field of information security, is described. Based on this paradigm a novel approach to anomaly detection is presented.
Aickelin, Uwe, Feyereisl, Jan
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N-terminal and C-terminal domains of calmodulin mediate FADD and TRADD interaction [PDF]
, 2015 FADD (Fas–associated death domain) and TRADD (Tumor Necrosis Factor Receptor 1-associated death domain) proteins are important regulators of cell fate in mammalian cells. They are both involved in death receptors mediated signaling pathways and have been
Balog, Edward M. +7 more
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Interaction between Cannabinoid System and Toll-Like Receptors Controls Inflammation [PDF]
, 2016 Since the discovery of the endocannabinoid system consisting of cannabinoid receptors, endogenous ligands, and biosynthetic and metabolizing enzymes, interest has been renewed in investigating the promise of cannabinoids as therapeutic agents.
McCoy, Kathleen L.
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Vaccinia virus protein A46R targets multiple Toll-like-interleukin-1 receptor adaptors and contributes to virulence [PDF]
, 2005 Viral immune evasion strategies target key aspects of the host antiviral response. Recently, it has been recognized that Toll-like receptors (TLRs) have a role in innate defense against viruses.
Bartlett, Nathan W +8 more
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Central pathways causing fatigue in neuro-inflammatory and autoimmune illnesses [PDF]
, 2015 The genesis of severe fatigue and disability in people following acute pathogen invasion involves the activation of Toll-like receptors followed by the upregulation of proinflammatory cytokines and the activation of microglia and astrocytes.
Berk, Michael +3 more
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Transcriptome Modifications in Porcine Adipocytes via Toll-Like Receptors Activation [PDF]
, 2019 Adipocytes are the most important cell type in adipose tissue playing key roles in immunometabolism. We previously reported that nine members of the Toll-like receptor (TLR) family are expressed in an originally established porcine intramuscular pre ...
Albarracín, Leonardo Miguel +13 more
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Ibrutinib Unmasks Critical Role of Bruton Tyrosine Kinase in Primary CNS Lymphoma. [PDF]
, 2017 Bruton tyrosine kinase (BTK) links the B-cell antigen receptor (BCR) and Toll-like receptors with NF-κB. The role of BTK in primary central nervous system (CNS) lymphoma (PCNSL) is unknown.
Brennan, Cameron W. +41 more
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Emerging role of endosomal toll-like receptors in rheumatoid arthritis [PDF]
, 2014 Toll-like receptors (TLRs) and their downstream signaling pathways have been comprehensively characterized in innate immunity. In addition to this function, these receptors have also been suggested to be involved in the pathogenesis of many autoimmune ...
Chamberlain, Giselle +2 more
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Identification of CNS Injury-Related microRNAs as Novel Toll-Like Receptor 7/8 Signaling Activators by Small RNA Sequencing [PDF]
, 2020 Toll-like receptors (TLRs) belong to pattern recognition receptors, which respond to danger signals such as pathogen-associated molecular patterns or damage-associated molecular patterns.
Buonfiglioli, Alice +7 more
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