Results 21 to 30 of about 310,367 (307)

Toll like receptors agonists-based nanomedicines as veterinary immunotherapies

Precision Nanomedicine, 2020
Many infections affecting animals enter across mucosa, needing of secretory immunity to reject the disease; protection against some pathogens must be early, fast, and specifically elicited, while from others must be wide enough to fight against ...
Federico L Parra, María J Morilla, Eder L Romero   +2 more
doaj   +1 more source

Involvement of Toll-Like Receptor 4 in Decreased Vasopressor Response Following Trauma/Hemorrhagic Shock

Critical Care Explorations, 2021
OBJECTIVES:. Refractory vascular failure due to the inability of vascular smooth muscle to respond to vasoconstrictors such as phenylephrine is a final common pathway for severe circulatory shock of any cause, including trauma/hemorrhagic shock ...
Rafi Mazor, PhD, Fernando Dos Santos, PhD, Joyce B. Li, MSc, Federico Aletti, PhD, Geert Schmid-Schonbein, PhD, Erik B. Kistler, MD, PhD   +5 more
doaj   +1 more source

Up-regulation of Toll-like receptors 2, 3 and 4 in allergic rhinitis

Respiratory Research, 2005
Background Toll-like receptors enable the host to recognize a large number of pathogen-associated molecular patterns such as bacterial lipopolysaccharide, viral RNA, CpG-containing DNA and flagellin.
Uddman Rolf, Jansson Lennart, Erjefält Jonas, Adner Mikael, Fransson Mattias, Cardell Lars-Olaf   +5 more
doaj   +1 more source

The Role of Toll Like Receptors in Pregnancy [PDF]

International Journal of Fertility and Sterility, 2013
For many years, the innate immunity was of less interest than the adaptive immunity because it was perceived to have secondary importance in the functionality of the immune system.
Elham Amirchaghmaghi, Seyed Abdolvahab Taghavi, Farnaz Shapouri, Shaghayegh Saeidi, Abbas Rezaei, Reza Aflatoonian   +5 more
doaj  

Toll-Like Receptors in Angiogenesis

The Scientific World Journal, 2011
Toll-like receptors (TLRs) are known as pattern-recognition receptors related to the Toll protein of Drosophila. After recognition of pathogen-associated molecular patterns of microbial origin, the TLRs alert the immune system, and initiate innate and ...
Karsten Grote, Harald Schütt, Bernhard Schieffer   +2 more
doaj   +1 more source

Identification of single nucleotide polymorphisms in Toll-like receptor candidate genes associated with tuberculosis infection in water buffalo (Bubalus bubalis) [PDF]

, 2014
Toll-like receptors play a key role in innate immunity by recognizing pathogens and activating appropriate responses. Pathogens express several signal molecules (pathogen-associated molecular patterns, PAMPs) essential for survival and pathogenicity ...
Acutis, Pier Luigi, Alfano, Flora, BARONE, AMALIA, Borriello, Giorgia, Desiato, Rosanna, Galiero, Giorgio, Lucibelli, Maria Gabriella, Maniaci, Maria Grazia, Pasquali, Paolo, Peletto, Simone, Tarantino, Michela, Urciuolo, Giovanna   +11 more
core   +1 more source

Serum amyloid A1 mediates myotube atrophy via Toll‐like receptors

Journal of Cachexia, Sarcopenia and Muscle, 2020
Background Critically ill patients frequently develop muscle atrophy and weakness in the intensive‐care‐unit setting [intensive care unit‐acquired weakness (ICUAW)]. Sepsis, systemic inflammation, and acute‐phase response are major risk factors.
Alexander Hahn, Melanie Kny, Cristina Pablo‐Tortola, Mihail Todiras, Michael Willenbrock, Sibylle Schmidt, Katrin Schmoeckel, Ilka Jorde, Marcel Nowak, Ernst Jarosch, Thomas Sommer, Barbara M. Bröker, Stephan B. Felix, Claus Scheidereit, Steffen Weber‐Carstens, Christian Butter, Friedrich C. Luft, Jens Fielitz   +17 more
doaj   +1 more source

Morphine activates neuroinflammation in a manner parallel to endotoxin [PDF]

, 2012
Opioids create a neuroinflammatory response within the CNS, compromising opioid-induced analgesia and contributing to various unwanted actions. How this occurs is unknown but has been assumed to be via classic opioid receptors.
A. A. Somogyi, A. J. de Jesus, A. Reddy, Barochia, Bevan, Bokhari, Dziarski, H. Yin, Hargreaves, Hoshino, Hutchinson, Hutchinson, Hutchinson, Hutchinson, Hutchinson, Hutchinson, J. Thomas, Jacquet, Joce, K. Cheng, K. Ramos, Kirikae, L. C. Loram, L. R. Watkins, Lewis, Li, Liu, Liu, M. R. Hutchinson, Manavalan, Milligan, Nagyoszi, Narita, Ohto, Park, Resman, Rice, Slivka, Takeuchi, Viriyakosol, Watkins, X. Wang, Youn   +42 more
core   +2 more sources

Toll-like Receptors [PDF]

, 2021
Toll-like receptors (TLRs) are pattern recognition receptors that allow innate immunity to protect our body against invading pathogens. They are alsoregulators of adaptive immunity.

core   +1 more source

Toll-like receptors in lupus nephritis

Journal of Biomedical Science, 2018
The pathogenesis of systemic autoimmune diseases such as systemic lupus erythematosus (SLE) is based on the loss of self-tolerance against ubiquitous autoantigens involving all mechanisms of adaptive immunity.
Satish Kumar Devarapu, Hans-Joachim Anders   +1 more
doaj   +1 more source