Results 21 to 30 of about 196,754 (276)
Critical Care Explorations, 2021 OBJECTIVES:. Refractory vascular failure due to the inability of vascular smooth muscle to respond to vasoconstrictors such as phenylephrine is a final common pathway for severe circulatory shock of any cause, including trauma/hemorrhagic shock ...
Rafi Mazor, PhD +5 more
doaj +1 more source
The Role of Toll Like Receptors in Pregnancy [PDF]
International Journal of Fertility and Sterility, 2013 For many years, the innate immunity was of less interest than the adaptive immunity because it was perceived to have secondary importance in the functionality of the immune system.
Elham Amirchaghmaghi +5 more
doaj
Up-regulation of Toll-like receptors 2, 3 and 4 in allergic rhinitis
Respiratory Research, 2005 Background Toll-like receptors enable the host to recognize a large number of pathogen-associated molecular patterns such as bacterial lipopolysaccharide, viral RNA, CpG-containing DNA and flagellin.
Uddman Rolf +5 more
doaj +1 more source
Toll-like receptors of deuterostome invertebrates
Frontiers in Immunology, 2012 Defensive systems against pathogens are responsible not only for survival or lifetime of an individual but also for the evolution of a species. Innate immunity is expected to be more important for invertebrates than mammals, given that adaptive immunity ...
Honoo eSatake, Toshio eSekiguchi
doaj +1 more source
Toll-like receptors in lupus nephritis
Journal of Biomedical Science, 2018 The pathogenesis of systemic autoimmune diseases such as systemic lupus erythematosus (SLE) is based on the loss of self-tolerance against ubiquitous autoantigens involving all mechanisms of adaptive immunity.
Satish Kumar Devarapu +1 more
doaj +1 more source
Toll-like receptors and atherosclerosis [PDF]
Medicinski Glasnik, 2009 Toll like receptors (TLR) are receptors with major role in activationof immune system by regulating production of chemokinesand cytokines, which makes them important in different types ofinflammatory reactions- bacterial, viral, parasitic, acute ...
Jerko Barbić +4 more
doaj
Toll-Like Receptors and Myocardial Inflammation
International Journal of Inflammation, 2011 Toll-like receptors (TLRs) are a member of the innate immune system. TLRs detect invading pathogens through the pathogen-associated molecular patterns (PAMPs) recognition and play an essential role in the host defense.
Yan Feng, Wei Chao
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background B‐acute lymphoblastic leukemia (B‐ALL) is the most common pediatric cancer, and while most children in high‐resource settings are cured, therapy carries risks for long‐term toxicities. Understanding parents’ concerns about these late effects is essential to guide anticipatory support and inform evolving therapeutic approaches ...
Kellee N. Parker +7 more
wiley +1 more source
Toll-like receptors as adjuvant receptors
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 2002 The mammalian Toll-like receptors (TLRs) are expressed on macrophages and dendritic cells, which are primarily involved in innate immunity. At present, ligands for several of the TLRs, such as TLR2, TLR3, TLR4, TLR5, TLR6, and TLR9, have been identified.
Kaisho, Tsuneyasu, Akira, Shizuo
openaire +2 more sources
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source