Results 11 to 20 of about 165,830 (263)

Serial Total Bile Acid Measurements in Intrahepatic Cholestasis of Pregnancy. [PDF]

Obstet Gynecol
Although peak serum total bile acid (TBA) levels guide management of intrahepatic cholestasis of pregnancy (ICP), whether ICP progresses in severity and when or how to assess bile acid levels serially remains unclear. We conducted a secondary analysis of a single-institution retrospective cohort study to assess bile acid trends across pregnancy among ...
Sarker MR, Ramos GA, Ferrara L, Debolt CA.   +3 more
europepmc   +6 more sources

Total serum bile acids or serum bile acid profile, or both, for the diagnosis of intrahepatic cholestasis of pregnancy [PDF]

Cochrane Database of Systematic Reviews, 2017
Intrahepatic cholestasis of pregnancy is a pregnancy-specific liver disorder, possibly associated with an increased risk of severe fetal adverse events. Total serum bile acids (TSBA) concentration, alone or in combination with serum aminotransferases, have been the most often used biomarkers for the diagnosis of intrahepatic cholestasis of pregnancy in
C. Manzotti, G. Casazza, T. Stimac, D. Nikolova, C. Gluud   +4 more
  +9 more sources

Measurement of total bile acids in gastric juice. [PDF]

Journal of Clinical Pathology, 1984
An established method for the assay of total bile acids was validated for use in fasting and post-prandial gastric juice samples. Fasting and post-prandial intragastric bile acid concentrations were measured in 29 healthy volunteers, 15 patients after vagotomy and gastrojejunostomy (V and GJ) and 15 patients after vagotomy and pyloroplasty (V and P ...
B J, Collins, P C, Watt, T, O'Reilly, R J, McFarland, A H, Love   +4 more
openaire   +2 more sources

Hepatic bile acids and bile acid-related gene expression in pregnant and lactating rats [PDF]

PeerJ, 2013
Background. Significant physiological changes occur during pregnancy and lactation. Intrahepatic cholestasis of pregnancy (ICP) is a liver disease closely related to disruption of bile acid homeostasis.
Qiong N. Zhu, Hong M. Xie, Dan Zhang, Jie Liu, Yuan F. Lu   +4 more
doaj   +2 more sources

Inclusion of Soluble Fiber During Gestation Regulates Gut Microbiota, Improves Bile Acid Homeostasis, and Enhances the Reproductive Performance of Sows

Frontiers in Veterinary Science, 2021
Interaction between the dietary fiber and the gut microbes can regulate host bile acid metabolism. This study sought to explore the effects of guar gum combined with pregelatinized waxy maize starch (GCW) in a gestation diet on reproductive performance ...
Xiaoyu Wu, Shengnan Yin, Chuanshang Cheng, Chuanhui Xu, Jian Peng, Jian Peng   +5 more
doaj   +1 more source

Measurement of sulfated and nonsulfated bile acids in human serum and urine

Journal of Lipid Research, 1974
Amberlite XAD-2 was used to extract bile acids from urine or diluted serum of patients with hepatobiliary diseases. Columns containing Sephadex LH-20 were then used to separate the sulfated and nonsulfated bile acids.
Isao Makino, Kenjiro Shinozaki, Shoichi Nakagawa, Keimei Mashimo   +3 more
doaj   +1 more source

A simple and sensitive assay of total serum bile acids

Clinica Chimica Acta, 1976
A simple and sensitive method was developed for the quantification of serum total 3alpha-hydroxy bile acids. 0.1 ml of serum was mixed with tris(hydroxymethyl) aminomethane hydrochloric acid buffer and heated at 67 degrees C for 30 min. To the solution were added 3alpha-hydroxysteroid : oxidoreductase (EC 1.1.1.50; 3alpha-HSD), NAD, diaphorase (EC 1.6 ...
MASHIGE, FUMIKO, YANAGISAWA, ETSUKO, OSUGA, TOSHIAKI   +2 more
openaire   +2 more sources

Bile acid and sterol metabolism with combined HMG-CoA reductase and PCSK9 suppression

Journal of Lipid Research, 2013
Proprotein convertase subtilisin-kexin-9 (PCSK9) inhibition markedly augments the LDL lowering action of statins. The combination is being evaluated for long-term effects on atherosclerotic disease outcomes.
Rex A. Parker, Ricardo Garcia, Carol S. Ryan, Xiaoqin Liu, Petia Shipkova, Valentin Livanov, Pritesh Patel, Siew P. Ho   +7 more
doaj   +1 more source

A fluorimetric and enzymatic method for the estimation of serum total bile acids [PDF]

Journal of Clinical Pathology, 1970
The enzymatic technique using 3α-hydroxysteroid dehydrogenase for determining bile acids in blood has been modified by measuring the reduced nicotinamide adenine dinucleotide fluorimetrically. The increased sensitivity attained enables the concentration of total bile acids in serum to be estimated using 3 ml for normal subjects and 1 ml for jaundiced ...
G M, Murphy, B H, Billing, D N, Baron
openaire   +2 more sources

Contraceptive steroids alter the steady-state kinetics of bile acids.

Journal of Lipid Research, 1988
Contraceptive steroids increase the ratio of cholic acid to chenodeoxycholic acid in bile. This alteration may contribute to the development of cholesterol gallstones.
G T Everson, P Fennessey, F Kern, Jr
doaj   +1 more source