Results 11 to 20 of about 1,891 (215)
Trimethylamine-N-oxide (TMAO)-induced atherosclerosis is associated with bile acid metabolism
Lipids in Health and Disease, 2018 Background Recently, trimethylamine-N-oxide (TMAO) plasma levels have been proved to be associated with atherosclerosis development. Among the targets aimed to ameliorating atherosclerotic lesions, inducing bile acid synthesis to eliminate excess ...
Lin Ding +7 more
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Hepatic bile acids and bile acid-related gene expression in pregnant and lactating rats [PDF]
PeerJ, 2013 Background. Significant physiological changes occur during pregnancy and lactation. Intrahepatic cholestasis of pregnancy (ICP) is a liver disease closely related to disruption of bile acid homeostasis.
Qiong N. Zhu +4 more
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Frontiers in Veterinary Science, 2021 Interaction between the dietary fiber and the gut microbes can regulate host bile acid metabolism. This study sought to explore the effects of guar gum combined with pregelatinized waxy maize starch (GCW) in a gestation diet on reproductive performance ...
Xiaoyu Wu +5 more
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A simple and sensitive assay of total serum bile acids
Clinica Chimica Acta, 1976 A simple and sensitive method was developed for the quantification of serum total 3alpha-hydroxy bile acids. 0.1 ml of serum was mixed with tris(hydroxymethyl) aminomethane hydrochloric acid buffer and heated at 67 degrees C for 30 min. To the solution were added 3alpha-hydroxysteroid : oxidoreductase (EC 1.1.1.50; 3alpha-HSD), NAD, diaphorase (EC 1.6 ...
MASHIGE, FUMIKO +2 more
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Measurement of sulfated and nonsulfated bile acids in human serum and urine
Journal of Lipid Research, 1974 Amberlite XAD-2 was used to extract bile acids from urine or diluted serum of patients with hepatobiliary diseases. Columns containing Sephadex LH-20 were then used to separate the sulfated and nonsulfated bile acids.
Isao Makino +3 more
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Bile acid and sterol metabolism with combined HMG-CoA reductase and PCSK9 suppression
Journal of Lipid Research, 2013 Proprotein convertase subtilisin-kexin-9 (PCSK9) inhibition markedly augments the LDL lowering action of statins. The combination is being evaluated for long-term effects on atherosclerotic disease outcomes.
Rex A. Parker +7 more
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Contraceptive steroids alter the steady-state kinetics of bile acids.
Journal of Lipid Research, 1988 Contraceptive steroids increase the ratio of cholic acid to chenodeoxycholic acid in bile. This alteration may contribute to the development of cholesterol gallstones.
G T Everson, P Fennessey, F Kern, Jr
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A fluorimetric and enzymatic method for the estimation of serum total bile acids [PDF]
Journal of Clinical Pathology, 1970 The enzymatic technique using 3α-hydroxysteroid dehydrogenase for determining bile acids in blood has been modified by measuring the reduced nicotinamide adenine dinucleotide fluorimetrically. The increased sensitivity attained enables the concentration of total bile acids in serum to be estimated using 3 ml for normal subjects and 1 ml for jaundiced ...
G M, Murphy, B H, Billing, D N, Baron
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Effect of bile duct ligation on bile acid metabolism in rats.
Journal of Lipid Research, 1981 The effect of bile duct ligation on the quantitative and qualitative changes of bile acids in serum, liver, urine, and feces, and the concentration of cholesterol and phospholipids in serum and liver were examined in male rats.
T Kinugasa +5 more
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Proton magnetic resonance assay of total and taurine-conjugated bile acids in bile
Journal of Lipid Research, 1999 Biliary bile acids, coexisting with phospholipid and cholesterol, are partly conjugated with taurine. In the present report we show that total and taurine-conjugated bile acids in bile can be simultaneously and quantitatively measured by high-resolution (1)H-nuclear magnetic resonance ((1)H-NMR) spectroscopy.
Hiroki Ishikawa +8 more
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