Results 21 to 30 of about 1,891 (215)
Makara Journal of Health Research, 2011 Excessive hepatocyte apoptosisinduced by bile acid accumulation occurred in severe obstructive jaundice, and impair the liver secretion function. The objective of this study is to determine whether the inhibition of bile acid accumulation through bile ...
Toar J. M. Lalisang +3 more
doaj +1 more source
Journal of Lipid Research, 1968 Fed cholestanol is converted by the rabbit to 5α-bile acids which coprecipitate with the normally occurring 5β-bile acids to form gallstones composed of calcium and sodium glycoallodeoxycholate and glycodeoxycholate.
Alan F. Hofmann +3 more
doaj +1 more source
Dietary Psyllium Increases Fecal Bile Acid Excretion, Total Steroid Excretion and Bile Acid Biosynthesis in Rats [PDF]
The Journal of Nutrition, 1998 Psyllium, a source of dietary fiber rich in soluble components results in lower serum cholesterol concentration in several species. Suggested mechanisms for the hypocholesterolemic effect include a greater excretion of fecal bile acids and total steroids, and up-regulation of bile acid biosynthesis.
K K, Buhman +3 more
openaire +2 more sources
Direct spectrophotometry of total bile acids in serum.
Clinical Chemistry, 1981 Abstract In this simple and direct method for determining total bile acids in serum, the serum was mixed with sodium pyruvate, a lactate dehydrogenase blocker, and bile acids were then measured spectrophotometrically after the following enzyme reaction.
F, Mashige +4 more
openaire +2 more sources
Perinatal bile acid metabolism: analysis of urinary bile acids in pregnant women and newborns
Journal of Lipid Research, 1997 The metabolism of bile acids in 30 pregnant women was evaluated by analyzing the urinary composition of bile acids during late gestation (weeks 30-41) and again in these women and their newborn infants during the first week after delivery.
A Kimura +9 more
doaj +1 more source
A Study of Serum Total Bile Acids in Pregnant Women
Journal of Integrated Health, 2023 Bile stasis, which is one of the hepatobiliary disorders during pregnancy, is manifested by symptoms such as itching, insomnia, fatigue, bleeding, and the amount of total bile acid increases in laboratory tests. Elevation of total bile acids is advantageous not only as a diagnostic criterion, but also as an assessment of fetal risks due to cholestasis.
D. Gerelmaa, T. Sarantuya
openaire +1 more source
Sevelamer inhibits the formation of cholesterol gallstones by modulating bile acid metabolism
Frontiers in PharmacologyBackgroundThe purpose of this study was to investigate the effect and mechanism of Sevelamer hydrochloride (Sev) on cholesterol gallstone formation via the intestinal Fxr-Fgf15 signaling pathway in a mouse model.MethodsA cholesterol gallstone mouse model
Shuang Shen +9 more
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
The human gut microbiome across the life course
FEBS Letters, EarlyView.Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
BMC Pregnancy and ChildbirthBackground Given the high prevalence of gestational diabetes mellitus and its significant impact on maternal and neonatal health, identifying reliable biomarkers for prediction and diagnosis is essential.
Mohammadamin Parsaei +5 more
doaj +1 more source