Results 51 to 60 of about 3,850,300 (360)

A Comprehensive Review on the Total Synthesis of Antibacterial Furanomycin and Its Analogs

Organics
l-(+)-Furanomycin 1 is a miniature antibacterial natural product that contains an α-amino acid core. This non-proteinogenic α-amino acid was first isolated in 1967 by Katagiri and co-workers from the fermentation broth of Streptomyces threomyceticus L ...
Rajendra Rohokale, Rajendra Mane
doaj   +1 more source

Psychological Safety Among Interprofessional Pediatric Oncology Teams in Germany: A Nationwide Survey

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Psychological safety (PS) is essential for teamwork, communication, and patient safety in complex healthcare environments. In pediatric oncology, interprofessional collaboration occurs under high emotional and organizational demands. Low PS may increase stress, burnout, and adverse events.
Alexandros Rahn, Anna‐Lena Herbach, Christian Bock, Katharina Fleig, Urs Mücke   +4 more
wiley   +1 more source

Recent advancements in the synthesis of Veratrum alkaloids

Beilstein Journal of Organic Chemistry
The Veratrum alkaloids constitute a class of natural products with particularly intricate polycyclic frameworks and dense stereochemistry and, thus, have stood long as benchmarks in chemical synthesis.
Morwenna Mögel, David Berger, Philipp Heretsch   +2 more
doaj   +1 more source

Recent Advances on Biological Activities and Structural Modifications of Dehydroabietic Acid

Toxins, 2022
Dehydroabietic acid is a tricyclic diterpenoid resin acid isolated from rosin. Dehydroabietic acid and its derivatives showed lots of medical and agricultural bioactivities, such as anticancer, antibacterial, antiviral, antiulcer, insecticidal, and ...
Meng Hao, Jianwei Xu, Houpeng Wen, Jiawei Du, Shaoyong Zhang, Min Lv, Hui Xu   +6 more
doaj   +1 more source

Total Synthesis of (‐)‐Stemonine. [PDF]

ChemInform, 2003
[reaction: see text] An enantioselective total synthesis of (-)-stemonine (1) is reported via a convergent assembly of the acyclic precursor 2. Key transformations include a Staudinger-aza-Wittig reaction to form the central perhydroazepine ring system and an iodine-induced tandem cyclization to construct the pyrrolidino-butyrolactone framework.
David R, Williams, Khalida, Shamim, Jayachandra P, Reddy, George S, Amato, Stephen M, Shaw   +4 more
openaire   +2 more sources

Total synthesis of aurofusarin: studies on the atropisomeric stability of bis-naphthoquinones [PDF]

, 2018
An efficient annulation involving pyrone addition to a quinone and Dieckmann condensation was developed for rapid assembly of a γ-naphthopyrone monomeric precursor to the bis-naphthoquinone natural product aurofusarin.
Allen, Ashley, Bao, Berkessel, Birchall, Bringmann, Bringmann, Chen, Corey, Crimmins, Dao, Donner, Dwyer, Flegel, Frandsen, Gao, Gray, Helder, Jew, Konkol, Lee, Leeper, Liau, Masson, Morishita, Natori, Romaine, Shi, Shibata, Shibata, Shibata, Shirakawa, Shirakawa, Sperry, Sun, Takeya, Takizawa, Varun, Wu, Yeung, Zeeck, Zhang, Ōki   +42 more
core   +1 more source

Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM

FEBS Letters, EarlyView.
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley   +1 more source

Total Synthesis of Natural Terpenoids Enabled by Cobalt Catalysis

Frontiers in Chemistry, 2022
Transition metal catalysis plays an essential role in the total synthesis of natural products. Cobalt-mediated asymmetric catalysis has successfully been used as a primary or a secondary step in the total synthesis of natural products, especially ...
Shu Xiao, Likun Ai, Qichang Liu, Baihui Yang, Jian Huang, Wei Xue, Yang Chen   +6 more
doaj   +1 more source

The first total synthesis of (+)-mucosin

, 2012
The first total synthesis of (+)-mucosin has been completed allowing assignment of the absolute stereochemistry of the natural product. A zirconium induced co-cyclisation was utilised to install the correct stereochemistry of the four contiguous ...
Henderson, Alan R., Owen, David R., Stec, Jozef, Whitby, Richard J.   +3 more
core   +1 more source

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source