Results 51 to 60 of about 12,937,378 (338)
Total Observed Organic Carbon (TOOC): A synthesis of North American observations [PDF]
Measurements of organic carbon compounds in both the gas and particle phases measured upwind, over and downwind of North America are synthesized to examine the total observed organic carbon (TOOC) over this region.
Aiken, A. C.+46 more
core +7 more sources
Enantioselective Total Synthesis of (–)-Myrifabral A and B [PDF]
A catalytic enantioselective approach to the Myrioneuron alkaloids (−)-myrifabral A and (−)-myrifabral B is described. The synthesis was enabled by a palladium-catalyzed enantioselective allylic alkylation, that generates the C(10) all-carbon quaternary ...
Bartberger, Michael D.+3 more
core
Total Synthesis of Panepophenanthrin [PDF]
[reaction: see text] The biomimetic synthesis of the racemic dimer panepophenanthrin was achieved in good yield employing a tandem reaction sequence.
Moses, J. E.+3 more
openaire +4 more sources
Total synthesis of jiadifenolide. [PDF]
As a potent neurotrophic agent, the sesquiterpenoid jiadifenolide represents a valuable small-molecule lead for the potential therapeutic treatment of neurodegenerative diseases.
Dalby, Stephen M+2 more
core +2 more sources
Recent progress on the total synthesis of acetogenins from Annonaceae
An overview of recent progress on the total synthesis of acetogenins from Annonaceae during the past 12 years is provided. These include mono-tetrahydrofurans, adjacent bis-tetrahydrofurans, nonadjacent bis-tetrahydrofurans, tri-tetrahydrofurans ...
Nianguang Li+4 more
doaj +1 more source
Marine Spirotetronates: Biosynthetic Edifices That Inspire Drug Discovery
Spirotetronates are actinomyces-derived polyketides that possess complex structures and exhibit potent and unexplored bioactivities. Due to their anticancer and antimicrobial properties, they have potential as drug hits and deserve further study.
Alexander A. Braddock+1 more
doaj +1 more source
Total Synthesis of (−)‐Caprazamycin A [PDF]
AbstractCaprazamycin A has significant antibacterial activity against Mycobacterium tuberculosis (TB). The first total synthesis is herein reported and features a) the scalable preparation of the syn‐β‐hydroxy amino acid with a thiourea‐catalyzed diastereoselective aldol reaction, b) construction of a diazepanone with an unstable fatty‐acid side chain,
Nakamura, Hugh+5 more
openaire +5 more sources
Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi+3 more
wiley +1 more source
First total synthesis of kipukasin A
In this paper, a practical approach for the total synthesis of kipukasin A is presented with 22% overall yield by using tetra-O-acetyl-β-D-ribose as starting material.
Chuang Li+4 more
doaj +1 more source