Results 51 to 60 of about 16,454,265 (355)
Total synthesis of (±)-paroxetine by diastereoconvergent cobalt-catalysed arylation
, 2014 A total synthesis of paroxetine is reported, with a diastereoselective and diastereoconvergent cobalt-catalysed sp3–sp2 coupling reaction involving a 3-substituted 4-bromo-N-Boc-piperidine (Boc = tert-butoxycarbonyl) substrate as a key step.
Despiau, Carole F. +3 more
core +2 more sources
Total synthesis of aurofusarin: studies on the atropisomeric stability of bis-naphthoquinones [PDF]
, 2018 An efficient annulation involving pyrone addition to a quinone and Dieckmann condensation was developed for rapid assembly of a γ-naphthopyrone monomeric precursor to the bis-naphthoquinone natural product aurofusarin.
Allen +42 more
core +1 more source
The first total synthesis of (+)-mucosin
, 2012 The first total synthesis of (+)-mucosin has been completed allowing assignment of the absolute stereochemistry of the natural product. A zirconium induced co-cyclisation was utilised to install the correct stereochemistry of the four contiguous ...
Henderson, Alan R. +3 more
core +1 more source
Organocatalysis in total synthesis [PDF]
, 2015 Peer ...
Herrera, Raquel P. +1 more
core +2 more sources
Pediatric Blood &Cancer, EarlyView.ABSTRACT Chemotherapy‐induced peripheral neuropathy remains a major complication in pediatric cancer, with disrupted somatosensory and nociceptive processing being a key aspect. This review synthesizes empirical studies on alterations in somatosensory and nociceptive processing in children and adolescents with cancer.
Julia Schweiger +4 more
wiley +1 more source
Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM
FEBS Letters, EarlyView.Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley +1 more source
Recent advancements in the synthesis of Veratrum alkaloids
Beilstein Journal of Organic ChemistryThe Veratrum alkaloids constitute a class of natural products with particularly intricate polycyclic frameworks and dense stereochemistry and, thus, have stood long as benchmarks in chemical synthesis.
Morwenna Mögel +2 more
doaj +1 more source
Total Synthesis of Cardenolides Acospectoside A and Acovenoside B
MoleculesAcospectoside A (1) and acovenoside B (2), two cytotoxic cardenolides extracted from the venomous South African bush Acokanthera oppositifolia, are distinguished by their unique structural motifs of the l-acovenose moiety at C-3 and a 1β-O-acetylated ...
Benzhang Liu, Peng Xu, Biao Yu
doaj +1 more source
Synthetic Approaches to the Lamellarins—A Comprehensive Review
Marine Drugs, 2014 The present review discusses the known synthetic routes to the lamellarin alkaloids published until 2014. It begins with syntheses of the structurally simpler type-II lamellarins and then focuses on the larger class of the 5,6-saturated and -unsaturated ...
Dennis Imbri +2 more
doaj +1 more source
Progress in the total synthesis of resin glycosides
Frontiers in Chemistry, 2022 Resin glycosides, mainly distributed in plants of the family Convolvulaceae, are a class of novel and complex glycolipids. Their structural complexity and significant biological activities have received much attention from synthetic chemists, and a ...
Wenli Wang +10 more
doaj +1 more source