Results 81 to 90 of about 14,944,148 (406)
Synthesis of the spiroketal core of integramycin
Beilstein Journal of Organic Chemistry, 2013 A concise synthetic strategy towards the spiroketal core of the HIV-integrase inhibitor integramycin (1) was developed. The required ketone precursor was efficiently constructed from two simple and easily accessible subunits by means of a ...
Evgeny. V. Prusov
doaj +1 more source
Synthetic Approaches to the Lamellarins—A Comprehensive Review
Marine Drugs, 2014 The present review discusses the known synthetic routes to the lamellarin alkaloids published until 2014. It begins with syntheses of the structurally simpler type-II lamellarins and then focuses on the larger class of the 5,6-saturated and -unsaturated ...
Dennis Imbri +2 more
doaj +1 more source
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Total Synthesis of (.+‐.)‐Garsubellin A. [PDF]
ChemInform, 2005 AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Akiyoshi, Kuramochi +4 more
openaire +2 more sources
Total Syntheses of Marine Natural Products Lyngbyabellin O and Lyngbyabellin P
Marine DrugsLyngbyabellins O and P are complex natural products derived from non-ribosomal peptide synthetase/polyketide synthase (NRPS/PKS) biosynthetic pathways and have been isolated from marine cyanobacterial sources.
Jing Chen, Shiyu Li, Chao Xu, Tao Ye
doaj +1 more source
A new member of the fusaricidin family – structure elucidation and synthesis of fusaricidin E
Beilstein Journal of Organic Chemistry, 2017 Two hitherto unknown fusaricidins were obtained from fermentation broths of three Paenibacillus strains. After structure elucidation based on tandem mass spectrometry and NMR spectroscopy, fusaricidin E was synthesized to confirm the structure and the ...
Marcel Reimann +5 more
doaj +1 more source
Total Synthesis and Metabolic Stability of Hispidulin and Its d-Labelled Derivative
Molecules, 2017 Hispidulin is a naturally occurring flavone known to have various Central nervous system (CNS) activities. Proposed synthetic approaches to synthesizing hispidulin have proven unsatisfactory due to their low feasibility and poor overall yields.
Liang-Chieh Chen +4 more
doaj +1 more source
Transport of apolipoproteins A-I and A-II by human thoracic duct lymph [PDF]
, 1981 The daily transport of human plasma apolipoproteins A-I and A-II, triglyceride, and total cholesterol from the thoracic duct lymph into plasma was measured in 2 subjects before and 3 subjects after renal transplantation. Lymph triglyceride transport was ~
Anderson, DW +8 more
core +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
MoleculesIsoflavones are a class of natural products that exhibit a wide range of interesting biological properties, including antioxidant, hepatoprotective, antimicrobial, and anti-inflammatory activities. Scandenone (1), osajin (2), and 6,8-diprenylgenistein (3)
Hongbo Dong +7 more
doaj +1 more source