Results 21 to 30 of about 1,089,122 (265)

Trained innate immunity and atherosclerosis [PDF]

Current Opinion in Lipidology, 2013
Item does not contain fulltextPURPOSE OF REVIEW: Monocytes/macrophages play a decisive role in the development and progression of atherosclerosis.
Leo A.B. Joosten, Bekkering, S., Jos W.M. van der Meer, Mihai G. Netea, Meer, J.W.M. van der, Joosten, L.A.B., Netea, M.G., Siroon Bekkering, Niels P. Riksen, Riksen, N.P.   +9 more
core   +4 more sources

Trained Immunity Carried by Non-immune Cells [PDF]

Frontiers in Microbiology, 2019
“Trained immunity” is a term proposed by Netea to describe the ability of an organism to develop an exacerbated immunological response to protect against a second infection independent of the adaptative immunity. This immunological memory can last from 1
Attoumani Hamada, Cédric Torre, Michel Drancourt, Eric Ghigo   +3 more
doaj   +4 more sources

Trained immunity in type 2 immune responses.

Mucosal Immunology, 2022
Immunological memory of innate immune cells, also termed "trained immunity", allows for cross-protection against distinct pathogens, but may also drive chronic inflammation.
Hartung, Franziska, Esser-von Bieren, J., Hartung, F., Esser-von Bieren, Julia   +3 more
core   +4 more sources

Induction of Trained Immunity by Recombinant Vaccines

Frontiers in Immunology, 2021
Vaccines represent an important strategy to protect humans against a wide variety of pathogens and have even led to eradicating some diseases. Although every vaccine is developed to induce specific protection for a particular pathogen, some vaccine ...
Camila Covián, Mariana Ríos, Roslye V. Berríos-Rojas, Susan M. Bueno, Alexis M. Kalergis, Alexis M. Kalergis   +5 more
doaj   +2 more sources

Trained innate immunity, epigenetics, and food allergy

Frontiers in Allergy, 2023
In recent years the increased incidence of food allergy in Western culture has been associated with environmental factors and an inappropriate immune phenotype.
Llilian Arzola-Martínez, Llilian Arzola-Martínez, Catherine Ptaschinski, Catherine Ptaschinski, Nicholas W. Lukacs, Nicholas W. Lukacs   +5 more
doaj   +2 more sources

Trained immunity: a revolutionary immunotherapeutic approach

Animal Diseases
Trained immunity is a phenomenon in which brief exposure to an infectious agent or a vaccine can induce long-lasting changes in the host's immune system, enhancing protection against subsequent infections.
Md. Salauddin, Sabuj Kanti Nath, Sukumar Saha, Qingcong Zheng, Chunfu Zheng, Md. Golzar Hossain   +5 more
doaj   +2 more sources

Trained immunity in organ transplantation. [PDF]

American Journal of Transplantation, 2020
Consistent induction of donor-specific unresponsiveness in the absence of continuous immunosuppressive therapy and toxic effects remains a difficult task in clinical organ transplantation.
Netea, Mihai G, Ochando, Jordi, Mulder, Willem J.M., Madsen, Joren C., Madsen, J.C., Netea, M.G., Netea, Mihai G., Fayad, Z.A., Fayad, Zahi A., Mulder, W.J., Mulder, Willem J M, Madsen, Joren C, Fayad, Zahi A, Ochando, J.   +13 more
core   +9 more sources

The role of trained immunity in sepsis

Frontiers in Immunology
Sepsis is defined as a life-threatening organ dysfunction syndrome caused by dysregulated host response to infection, characterized by a systemic inflammatory response to infection.
Wenjuan Wang, Lisi Ma, Bin Liu, Liangliang Ouyang   +3 more
doaj   +3 more sources

Trained immunity: A new player in cancer immunotherapy [PDF]

eLife
In the past, immune memory was considered an exclusive feature of the adaptive immune system. However, accumulating evidence suggests that the innate immune system, the most primitive and fundamental component of immunity, can mount more robust responses
Shu Li, Yi Zou, Austin McMasters, Fuxiang Chen, Jun Yan   +4 more
doaj   +2 more sources

Effector-Triggered Trained Immunity: An Innate Immune Memory to Microbial Virulence Factors?

Toxins, 2022
In the last decade, a major dogma in the field of immunology has been called into question by the identification of a cell autonomous innate immune memory.
Cedric Torre, Laurent Boyer
doaj   +1 more source