Results 11 to 20 of about 23,538 (242)
Colostrogenesis: IgG1 Transcytosis Mechanisms [PDF]
Journal of Mammary Gland Biology and Neoplasia, 2014 Biological transport of intact proteins across epithelial cells has been documented for many absorptive and secretory tissues. Immunoglobulins were some of the earliest studied proteins in this category.
Baumrucker, Craig +3 more
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Transcytosis in the development and morphogenesis of epithelial tissues
The EMBO Journal, 2021 Transcytosis is a form of specialized transport through which an extracellular cargo is endocytosed, shuttled across the cytoplasm in membrane‐bound vesicles, and secreted at a different plasma membrane surface.
Serra, Nicholas D +3 more
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Albumin transcytosis in mesothelium
American Journal of Physiology-Lung Cellular and Molecular Physiology, 2002 Apparent permeability to albumin (P(alb)) was measured with (125)I-albumin in specimens of rabbit parietal pericardium from lumen to interstitium (L-I) and from interstitium to lumen (I-L). With albumin concentration (C(alb)) 0.5%, P(alb) (x 10(-5) cm/s)
E. Agostoni, L. Zocchi, F. Bodega
core +6 more sources
Albumin transcytosis from the pleural space
Journal of Applied Physiology, 2002 Occurrence of transcytosis in pleural mesothelium was verified by measuring removal of labeled macromolecules from pleural liquid in experiments without and with nocodazole.
E. Agostoni, L. Zocchi, F. Bodega
core +4 more sources
Caveolae-Mediated Transcytosis and Its Role in Neurological Disorders
BiomoleculesThe blood–brain barrier (BBB) controls the flow of substances to maintain a homeostatic environment in the brain, which is highly regulated and crucial for the normal function of the central nervous system (CNS). Brain endothelial cells (bECs), which are
Kunjian Yang +4 more
doaj +2 more sources
Epithelial transcytosis of immunoglobulins
Journal of Mammary Gland Biology and Neoplasia, 1998 Transcytosis plays a central role in the immunological functions of epithelia, including the sampling of antigens that enter the body via the digestive, respiratory and urogenital tracts and their presentation to underlying lymphoid tissues, the ...
Hunziker, W., Kraehenbuhl, J. P.
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Transcytosis of Nanomedicine for Tumor Penetration
Nano Letters, 2019 The diffusion of nanomedicines used to treat tumors is severely hindered by the microenvironment, which is a challenge that has emerged as a bottleneck for the effective outcome of nanotherapies.
Fanqiang Meng (4786071) +9 more
core +3 more sources
Stimuli‐Responsive Nanocarriers for Transcytosis‐Based Cancer Drug Delivery
Advanced NanoBiomed ResearchSignificant challenges persist in enhancing the delivery efficiency of tumor nanomedicines, predominantly due to the difficulty of successfully surpassing pathophysiological barriers.
Zhehao Wang +3 more
doaj +2 more sources
Caveolae and transcytosis in endothelial cells: Role in atherosclerosis
Cell and Tissue Research, 2009 The endothelium plays an important role in the regulation of molecular exchanges between the blood and peripheral tissues. The transport of molecules between tissues must be tightly controlled in order to maintain homeostasis between the different organs
Frank, Philippe, +6 more
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Bifunctional molecules that induce targeted degradation and transcytosis of extracellular proteins in brain cells [PDF]
, 2023 We present the application of Angiopep-2 as a molecular degrader of extracellular proteins (MoDE) promoting target protein removal by both transcytosis and lysosomal degradation mechanisms in brain endothelial cells.
David, McDonald +3 more
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