Results 31 to 40 of about 23,538 (242)
The Role of BAR Proteins and the Glycocalyx in Brain Endothelium Transcytosis
Cells, 2020 Within the brain, endothelial cells lining the blood vessels meticulously coordinate the transport of nutrients, energy metabolites and other macromolecules essential in maintaining an appropriate activity of the brain.
Diana M. Leite +2 more
doaj +1 more source
Overview of Crosstalk Between Multiple Factor of Transcytosis in Blood Brain Barrier
Frontiers in Neuroscience, 2020 Blood brain barrier (BBB) conserves unique regulatory system to maintain barrier tightness while allowing adequate transport between neurovascular units.
Marco Tjakra +6 more
doaj +1 more source
Endothelial Transcytosis of Lipoproteins in Atherosclerosis [PDF]
Frontiers in Cardiovascular Medicine, 2018 Seminal studies from Nikolai Anichckov identified the accumulation of cholesterol in the arteries as the initial event that lead to the formation of atherosclerotic plaques. Further studies by Gofman and colleagues demonstrated that high levels of circulating low-density lipoprotein cholesterol (LDL-C) was responsible for the accelerated ...
Xinbo Zhang +2 more
openaire +3 more sources
PLoS Pathogens, 2013 The mechanisms by which human immunodeficiency virus type 1 (HIV-1) crosses mucosal surfaces to establish infection are unknown. Acidic genital secretions of HIV-1-infected women contain HIV-1 likely coated by antibody.
Sandeep Gupta +18 more
doaj +1 more source
A human blood-brain barrier transcytosis assay reveals antibody transcytosis influenced by pH-dependent receptor binding. [PDF]
, 2014 We have adapted an in vitro model of the human blood-brain barrier, the immortalized human cerebral microvascular endothelial cells (hCMEC/D3), to quantitatively measure protein transcytosis.
Claudia Baumgartner +5 more
core +1 more source
Transcytosis of Staphylococcal Superantigen Toxins [PDF]
The Journal of Experimental Medicine, 1997 Staphylococcus aureus produces a set of proteins (e.g., staphylococcal enterotoxin A [SEA], SEB, toxic shock syndrome toxin 1 [TSST-1]) which act both as superantigens (SAgs) and toxins. Although their mode of action as SAgs is well understood, little is known about how they enter the body via the intestine and cause food poisoning.
A R, Hamad, P, Marrack, J W, Kappler
openaire +2 more sources
Advanced Science, 2022 Bile acid‐modified nanoparticles provide a convenient strategy to improve oral bioavailability of poorly permeable drugs by exploiting specific interactions with bile acid transporters.
Feiyang Deng +3 more
doaj +1 more source
Microplastics as Emerging Neurotoxins: Brain Accumulation, Neuroinflammation, and Neurodegeneration Risk. [PDF]
J Biochem Mol ToxicolMicroplastics and nanoplastics (MPs/NPs) are emerging environmental neurotoxicants capable of accumulating in the human brain through blood‐brain barrier transcytosis and olfactory transport pathways. Once within the central nervous system, MPs/NPs trigger interconnected mechanisms including NLRP3 inflammasome activation, oxidative stress ...
Sophian A, Asmariani, Ismayani E.
europepmc +2 more sources
Storax Inhibits Caveolae-Mediated Transcytosis at Blood-Brain Barrier After Ischemic Stroke in Rats
Frontiers in Pharmacology, 2022 Background and Purpose: Blood-brain barrier (BBB) disruption following ischemic stroke (IS) contributes to hemorrhagic transformation, brain edema, increased neural dysfunction, secondary injury, and mortality.
Min Zhou +6 more
doaj +1 more source
Powerful transcytosis ability of Leptospira through HUVEC monolayer.
, 2022 A: Laser confocal microscopic 3D-image reflecting L. interrogans strain Lai transmigrating HUVEC monolayer for the indicated times. The green plaques indicate the cell monolayers. The black plaques indicate the nuclus.
Yaling Yang (746000) +6 more
core +1 more source