Results 41 to 50 of about 37,961 (284)
Electron tomography of late stages of FcRn-mediated antibody transcytosis in neonatal rat small intestine [PDF]
, 2012 The neonatal Fc receptor (FcRn) transports maternal immunoglobulin (IgG) across epithelia to confer passive immunity to mammalian young. In newborn rodents, FcRn transcytoses IgG from ingested milk across the intestinal epithelium for release into the ...
Bjorkman, Pamela J. +2 more
core +2 more sources
Hormone-stimulated modulation of endocytic trafficking in osteoclasts [PDF]
, 2012 Copyright @ 2012 Stenbeck, Lawrence and Albert. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in other forums, provided the original authors and ...
Albert, AP, Lawrence, KM, Stenbeck, G
core +2 more sources
Drug delivery in overcoming the blood-brain barrier: role of nasal mucosal grafting [PDF]
, 2017 The blood–brain barrier (BBB) plays a fundamental role in protecting and maintaining the homeostasis of the brain. For this reason, drug delivery to the brain is much more difficult than that to other compartments of the body. In order to bypass or cross
Carafa, Maria +5 more
core +1 more source
Role of Polymeric Immunoglobulin Receptor in IgA and IgM Transcytosis
International Journal of Molecular Sciences, 2021 Transcytosis of polymeric IgA and IgM from the basolateral surface to the apical side of the epithelium and subsequent secretion into mucosal fluids are mediated by the polymeric immunoglobulin receptor (pIgR).
Hao Wei, Ji-Yang Wang
semanticscholar +1 more source
Suppression of transcytosis regulates zebrafish blood-brain barrier function
eLife, 2019 As an optically transparent model organism with an endothelial blood-brain barrier (BBB), zebrafish offer a powerful tool to study the vertebrate BBB. However, the precise developmental profile of functional zebrafish BBB acquisition and the subcellular ...
Natasha M O'Brown +2 more
doaj +1 more source
Frontiers in Neuroscience, 2022 The blood-brain barrier (BBB) comprises a single layer of endothelial cells and maintains a safe and homeostatic environment for proper neuronal function and synaptic transmission.
Wei Li +8 more
doaj +1 more source
Nature Communications, 2021 Effective treatments of neurodegenerative diseases require drugs to be actively transported across the blood-brain barrier (BBB). However, nanoparticle drug carriers explored for this purpose show negligible brain uptake, and the lack of basic ...
K. Kucharz +7 more
semanticscholar +1 more source
Colostrogenesis: IgG1 Transcytosis Mechanisms
Journal of Mammary Gland Biology and Neoplasia, 2014 Biological transport of intact proteins across epithelial cells has been documented for many absorptive and secretory tissues. Immunoglobulins were some of the earliest studied proteins in this category. The transcellular transport (transcytosis) of immunoglobulins in neonatal health and development has been recognized; the process is especially ...
Baumrucker, Craig, Bruckmaier, Rupert
openaire +3 more sources
Endothelial Transcytosis of Lipoproteins in Atherosclerosis [PDF]
Frontiers in Cardiovascular Medicine, 2018 Seminal studies from Nikolai Anichckov identified the accumulation of cholesterol in the arteries as the initial event that lead to the formation of atherosclerotic plaques. Further studies by Gofman and colleagues demonstrated that high levels of circulating low-density lipoprotein cholesterol (LDL-C) was responsible for the accelerated ...
Xinbo Zhang +2 more
openaire +3 more sources
Development of Functional Microfold (M) Cells from Intestinal Stem Cells in Primary Human Enteroids. [PDF]
, 2016 Background & aimsIntestinal microfold (M) cells are specialized epithelial cells that act as gatekeepers of luminal antigens in the intestinal tract.
Dunn, James CY +11 more
core +7 more sources