Results 61 to 70 of about 23,538 (242)
Advanced Materials for Biologics Delivery to Brain Tumors
Advanced Materials, EarlyView.Material innovation is central to unlocking the therapeutic potential of biologics against many central nervous system diseases, including brain cancer. By engineering carriers with controlled transport, targeting, and release properties, advanced materials can overcome the blood–brain barrier and tumor microenvironment, improving the delivery of ...
Yuran Feng +4 more
wiley +1 more source
Epstein-Barr Virus Transcytosis through Polarized Oral Epithelial Cells [PDF]
, 2013 Although Epstein-Barr virus (EBV) is an orally transmitted virus, viral transmission through the oropharyngeal mucosal epithelium is not well understood.
Palefsky, Joel M +2 more
core +1 more source
Advanced Materials, EarlyView.A cholesterol‐conjugated lipid library enabled the identification of a ligand‐free LNP platform for efficient mRNA delivery to brain endothelial cells via systemic administration. This platform achieves selective BBB targeting without disrupting barrier integrity, and enables modulation of neuroinflammation and vascular function without requiring trans‐
Zeru Tian +7 more
wiley +1 more source
Frontiers in Microbiology, 2021 Cronobacter sakazakii (C. sakazakii) is an emerging opportunistic foodborne pathogen that can cause neonatal necrotizing enterocolitis, meningitis, sepsis in neonates and infants with a relatively high mortality rate.
Tong Jin +6 more
doaj +1 more source
IgG transcytosis in endothelial cells (in vitro data).
, 2023 IgG transcytosis in endothelial cells (in vitro data).
Remziye E. Wessel (17350784) +1 more
core +1 more source
FABP7: a glial integrator of sleep, circadian rhythms, plasticity, and metabolic function
Frontiers in Systems Neuroscience, 2023 Sleep and circadian rhythms are observed broadly throughout animal phyla and influence neural plasticity and cognitive function. However, the few phylogenetically conserved cellular and molecular pathways that are implicated in these processes are ...
Jason R. Gerstner +8 more
doaj +1 more source
Modulation of miR‐23b Wnt/β‐catenin Axis Strengthens Endothelial Barrier Properties
Advanced Science, EarlyView.Early blood‐brain barrier (BBB) disruption contributes to stroke and CNS disease pathology. miR‐23b was identified as a regulator of BBB integrity in brain endothelial cells. Inhibition of miR‐23b enhanced barrier‐associated properties, promoted repair‐related signaling, and reduced BBB leakage in experimental stroke models, supporting further ...
Victor Anthony Martinez +16 more
wiley +1 more source
M CELLS ARE THE IMPORTANT POST IN THE INITIATION OF IMMUNE RESPONSE IN INTESTINE
Инфекция и иммунитет, 2018 Microfold cells (M cells) are specialized intestinal epithelial cells that initiate mucosal immune responses. These unique phagocytic epithelial cells are specialized for the transfer of a broad range of particulate antigens and microorganisms across the
A. S. Bykov +7 more
doaj +1 more source
Smart Nanotechnologies for Multimodal Neuromodulation and Brain Interfacing
Advanced Science, EarlyView.Recent advances in smart nanotechnologies are expanding the toolbox for brain interfacing, from wireless neuromodulation and high‐resolution sensing to targeted delivery within the central nervous system. By combining responsive nanomaterials with bioinspired design, these platforms enable multimodal interactions with neurons and glia, while also ...
Tommaso Curiale +6 more
wiley +1 more source
Regulation of Transcytosis Underlies Blood-Brain Barrier Permeability
, 2019 The blood-brain barrier (BBB) provides a constant homeostatic brain environment that is essential for proper neural function. A single layer of continuous endothelial cells lining the walls of central nervous system (CNS) blood vessels forms the BBB ...
Andreone, Benjamin
core +4 more sources