Results 1 to 10 of about 122,409 (259)

Frequency of CD39+, LAG3+, and CTLA4+ Regulatory T Cells in Two Different Immunosuppressive Protocols in Renal Allograft Recipients (Sirolimus vs Mycophenolate mofetil): A Cohort Report [PDF]

Iranian Journal of Immunology, 2022
Background: Impaired renal function is considered as a significant risk factor for cardiovascular events in chronic kidney disease patients. Several immunosuppressive drugs are used in these patients, which necessitates to minimize the drug-related side ...
Yaghoub Mollaei-Kandelous, Pedram Ahmadpoor, Mohsen Nafar, Mohammad Reza Khatami, Samad Farashi Bonab, Nader Tajik, Mahdi Shekarabi, Aliakbar Amirzargar   +7 more
doaj   +1 more source

How sphingolipids affect T cells in the resolution of inflammation

Frontiers in Pharmacology, 2022
The concept of proper resolution of inflammation rather than counteracting it, gained a lot of attention in the past few years. Re-assembly of tissue and cell homeostasis as well as establishment of adaptive immunity after inflammatory processes are the ...
Jennifer Christina Hartel, Jennifer Christina Hartel, Nadine Merz, Sabine Grösch, Sabine Grösch   +4 more
doaj   +1 more source

Facilitating Success: Using Self-Regulated Learning and Servant Leadership in the College Classroom

Journal of Teaching and Learning with Technology, 2020
Student-centered pedagogy shifts the power dynamics, function of content, role of the educator, responsibility for learning, and purpose of evaluation (Weimer, 2013) within the classroom.
Michelle Lynn Clemons, Treg Hopkins
doaj   +1 more source

Intrauterine administration of peripheral blood mononuclear cells (PBMCs) improves embryo implantation in mice by regulating local Treg/Th17 cell balance

The Journal of Reproduction and Development, 2021
Immune imbalance of Treg/Th17 cells may contribute to recurrent implantation failure (RIF) during in vitro fertilization and embryo transfer (IVF-ET). In this study, we sought to determine the effect of intrauterine administration of mouse PBMCs prior to
Lei FAN, Menghan SHA, Wei LI, Qingling KANG, Jianli WU, Suhua CHEN, Nan YU   +6 more
doaj   +1 more source

IL36 Cooperates With Anti-CTLA-4 mAbs to Facilitate Antitumor Immune Responses

Frontiers in Immunology, 2020
Despite the great impact on long-term survival of some cancer patients, the immune checkpoint blockade (ICB) therapy is limited by its low response rates for most cancers.
Qiuxia Qu, Zhiwei Zhai, Jieni Xu, Song Li, Cheng Chen, Binfeng Lu, Binfeng Lu   +6 more
doaj   +1 more source

Evaluation of the functional activity of CD39 ectonucleotidase in regulatory T cells in children with inflammatory bowel diseases

Медицинская иммунология, 2023
In connection with the increasing incidence and prevalence of inflammatory bowel disease (IBD), the search for prognostic markers of the effectiveness of therapy is an urgent problem. An imbalance between Th17 lymphocytes and regulatory T cells (Treg) is
T. V. Radygina, E. G. Sorokina, S. V. Petrichuk, D. G. Kuptsova, O. V. Kurbatova, A. S. Potapov, S. A. Afanasyeva   +6 more
doaj   +1 more source

Content of CD4⁺T cell subpopulations in predicting the efficacy of biological therapy for psoriasis in children

Медицинская иммунология, 2023
Psoriasis is a chronic inflammatory skin disease characterized by increased proliferation of epidermal cells, impaired keratinization and an inflammatory reaction in dermis caused by activation of T lymphocytes and synthesis of pro-inflammatory cytokines.
D. G. Kuptsova, T. V. Radigina, O. V. Kurbatova, A. I. Materikin, R. V. Epishev, L. A. Opryatin, A. A. Khotko, N. N. Murashkin, S. V. Petrichuk   +8 more
doaj   +1 more source

Regulatory T-cells and allogeneic hematopoietic stem cell transplantation

Трансплантология (Москва), 2022
The article has summarized the available data about regulatory T cells, describing in-detail the stages of their studying, their development, classification, mechanisms of immunosuppression in general terms and also in the context of allogeneic ...
O. S. Karavaeva, M. Yu. Drokov, E. G. Khamaganova   +2 more
doaj   +1 more source

Immune-Phenotyping and Transcriptomic Profiling of Peripheral Blood Mononuclear Cells From Patients With Breast Cancer: Identification of a 3 Gene Signature Which Predicts Relapse of Triple Negative Breast Cancer

Frontiers in Immunology, 2018
Background: Interactions between the immune system and tumors are highly reciprocal in nature, leading to speculation that tumor recurrence or therapeutic resistance could be influenced or predicted by immune events that manifest locally, but can be ...
Gemma A. Foulds, Jayakumar Vadakekolathu, Tarek M. A. Abdel-Fatah, Divya Nagarajan, Stephen Reeder, Catherine Johnson, Simon Hood, Paul M. Moseley, Stephen Y. T. Chan, A. Graham Pockley, Sergio Rutella, Stephanie E. B. McArdle   +11 more
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Reprogrammed CD4+ T Cells That Express FoxP3+ Control Inhibitory Antibody Formation in Hemophilia A Mice

Frontiers in Immunology, 2019
Coagulation Factor VIII (FVIII) replacement therapy in hemophilia A patients is complicated by the development of inhibitory antibodies, which often render the treatment ineffective. Previous studies demonstrated a strong correlation between induction of
Roland W. Herzog, Veronica Kuteyeva, Rania Saboungi, Cox Terhorst, Moanaro Biswas   +4 more
doaj   +1 more source