Results 1 to 10 of about 275,584 (397)

Oral tolerance to cancer can be abrogated by T regulatory cell inhibition [PDF]

, 2014
Oral administration of tumour cells induces an immune hypo-responsiveness known as oral tolerance. We have previously shown that oral tolerance to a cancer is tumour antigen specific, non-cross-reactive and confers a tumour growth advantage.
A Micheli, AB Castro-Junior, AM Faria, Barbara-ann Guinn, DJ Needham, Garrett Casey, Gerald C. O'Sullivan, H Nishikawa, HL Weiner, HL Weiner, HY Wang, J Larkin, J Murphy, John O. Larkin, L Chen, Maria C. Whelan, Mark Tangney, MC Whelan, MG O'Brien, P Castro-Sanchez, RB Nussenblatt, SA Collins, SD Khare, V Boncheva, Valli De Re, X Wang, Y Chen, Y Zhang   +27 more
core   +16 more sources

Regulatory T-cells and allogeneic hematopoietic stem cell transplantation

Трансплантология (Москва), 2022
The article has summarized the available data about regulatory T cells, describing in-detail the stages of their studying, their development, classification, mechanisms of immunosuppression in general terms and also in the context of allogeneic ...
O. S. Karavaeva, M. Yu. Drokov, E. G. Khamaganova   +2 more
doaj   +1 more source

Facilitating Success: Using Self-Regulated Learning and Servant Leadership in the College Classroom

Journal of Teaching and Learning with Technology, 2020
Student-centered pedagogy shifts the power dynamics, function of content, role of the educator, responsibility for learning, and purpose of evaluation (Weimer, 2013) within the classroom.
Michelle Lynn Clemons, Treg Hopkins
doaj   +1 more source

Intrauterine administration of peripheral blood mononuclear cells (PBMCs) improves embryo implantation in mice by regulating local Treg/Th17 cell balance

The Journal of Reproduction and Development, 2021
Immune imbalance of Treg/Th17 cells may contribute to recurrent implantation failure (RIF) during in vitro fertilization and embryo transfer (IVF-ET). In this study, we sought to determine the effect of intrauterine administration of mouse PBMCs prior to
Lei FAN, Menghan SHA, Wei LI, Qingling KANG, Jianli WU, Suhua CHEN, Nan YU   +6 more
doaj   +1 more source

LKB1 Positively Regulates Dendritic Cell-induced T Cell Immunity and Suppresses Tumor Development [PDF]

Iranian Journal of Immunology, 2023
Background: The functions of dendritic cells (DCs) are influenced by their intracellular metabolism, in which liver kinase B1 (LKB1) plays an important role.
Wenjie Zhang, Shan Liu, Lin Zhao, Juncheng Wang, Meng Liu, Fengge Wang, Yuekang Xu   +6 more
doaj   +1 more source

How sphingolipids affect T cells in the resolution of inflammation

Frontiers in Pharmacology, 2022
The concept of proper resolution of inflammation rather than counteracting it, gained a lot of attention in the past few years. Re-assembly of tissue and cell homeostasis as well as establishment of adaptive immunity after inflammatory processes are the ...
Jennifer Christina Hartel, Jennifer Christina Hartel, Nadine Merz, Sabine Grösch, Sabine Grösch   +4 more
doaj   +1 more source

Evaluation of the functional activity of CD39 ectonucleotidase in regulatory T cells in children with inflammatory bowel diseases

Медицинская иммунология, 2023
In connection with the increasing incidence and prevalence of inflammatory bowel disease (IBD), the search for prognostic markers of the effectiveness of therapy is an urgent problem. An imbalance between Th17 lymphocytes and regulatory T cells (Treg) is
T. V. Radygina, E. G. Sorokina, S. V. Petrichuk, D. G. Kuptsova, O. V. Kurbatova, A. S. Potapov, S. A. Afanasyeva   +6 more
doaj   +1 more source

Treg Cells in Ischemic Stroke: A Small Key to a Great Orchestrion [PDF]

Клиническая практика, 2023
Ischemic stroke is a global medical problem and one of the leading causes of death or disability worldwide. The main approach of ischemic stroke therapy in the most acute period, which can prevent or minimize the development of a neurological deficit, is
Oksana A. Zhukova, Daria A. Chudakova, Vladimir V. Belopasov, Еlena V. Shirshova, Vladimir P. Baklaushev, Gaukhar M. Yusubalieva   +5 more
doaj   +1 more source

Content of CD4⁺T cell subpopulations in predicting the efficacy of biological therapy for psoriasis in children

Медицинская иммунология, 2023
Psoriasis is a chronic inflammatory skin disease characterized by increased proliferation of epidermal cells, impaired keratinization and an inflammatory reaction in dermis caused by activation of T lymphocytes and synthesis of pro-inflammatory cytokines.
D. G. Kuptsova, T. V. Radigina, O. V. Kurbatova, A. I. Materikin, R. V. Epishev, L. A. Opryatin, A. A. Khotko, N. N. Murashkin, S. V. Petrichuk   +8 more
doaj   +1 more source

Plasmodium yoelii infection of BALB/c mice results in expansion rather than induction of CD4+ Foxp3+ regulatory T cells [PDF]

, 2016
Recently, we demonstrated elevated numbers of CD4(+) Foxp3(+) regulatory T (Treg) cells in Plasmodium yoelii‐infected mice contributing to the regulation of anti‐malarial immune response. However, it remains unclear whether this increase in Treg cells is
Abel, S., Buer, J., Hansen, W., Hose, M., Hutzler, M., Kehrmann, J., Matuschewski, K., Tatura, R., Ueffing, K., Westendorf, A.   +9 more
core   +1 more source