Results 91 to 100 of about 174,092 (264)
The Role of Food Allergy in Eosinophilic Esophagitis
Journal of Asthma and Allergy, 2020 Jeffrey M Wilson, Rung-chi Li, Emily C McGowan Division of Allergy and Immunology, University of Virginia, Charlottesville, VA, USACorrespondence: Jeffrey M WilsonDivision of Allergy & Clinical Immunology, University of Virginia, Charlottesville, VA ...
Wilson JM, Li R, McGowan EC
doaj
Fragile Treg cells: Traitors in immune homeostasis?
Regulatory T (Treg) cells play a key role in maintaining immune tolerance and tissue homeostasis. However, in some disease microenvironments, Treg cells exhibit fragility, which manifests as preserved FoxP3 expression accompanied by inflammation and loss
Yumeng Zhu +7 more
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Analysis by manual gating of CD38+ Treg and total Treg cells.
, 2023 Graphs represent individual values and correlation between Severity Score groups and subset percentages (a) and absolute numbers (b) of CD38+ Treg. Percentage (c) and absolute numbers (d) of total Treg cells.
Esther Bernaldo-de-Quirós (12547435) +12 more
core +1 more source
Advanced Science, EarlyView.Lactate accumulation in glioblastoma drives lactylation of STING at lysine 370, a primate‐conserved residue. K370 lactylation weakens STING‐TBK1 binding, destabilizes STING, and disrupts ER‐to‐Golgi trafficking, blunting type I interferon signaling. LDHA inhibition reverses K370 lactylation and improves the antitumor efficacy of STING agonism combined ...
Yueyao Wu +11 more
wiley +1 more source
Expression of IFN-γ, TNF-α, IL17 in Treg of PBLs or in expanded Treg.
, 2013 Cells from PBMCs and expanded Treg on Day 14 after anti-CD3/CD28 activation were stained with indicated antibodies following stimulation with PMA/ionomycin for 5 h and analyzed by FACS.
Weiting Du (284095) +6 more
core +1 more source
The Dynamics of Treg/Th17 and the Imbalance of Treg/Th17 in Clonorchis sinensis-Infected Mice. [PDF]
, 2015 Clonorchiasis, caused by the liver fluke Clonorchis sinensis, is a chronic parasitic infection regulated by T cell subsets. An imbalance of CD4+CD25+ Foxp3+regulatory T (Treg) and interleukin (IL)-17-secreting T cells (Th17) may control inflammation and ...
Chao Yan (150844) +35 more
core +1 more source
Advanced Science, EarlyView.A novel PLGA/PBAE polymer microparticle platform revolutionizes intermediate‐stage liver cancer treatment by co‐delivering panobinostat and IL‐12 via a single TACE‐like injection. This sustained‐release system overcomes tumor immunosuppression, triggers robust innate and adaptive immune responses, and establishes tertiary lymphoid structures ...
Hongzhe Yu +7 more
wiley +1 more source
Immunomodulatory Effect of Fennel in Animal Model of Polycystic Ovarian Syndrome
Majallah-i dānishgāh-i ̒ulūm-i pizishkī-i Arāk, 2020 Background and Aim: Fennel with phytoestrogenic, antioxidant and anti-diabetic properties is used in traditional Iranian medicine to treat Polycystic Ovarian Syndrome (PCOS).
Ensieh Seif Amirhoseiny +3 more
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Chinese Journal of Lung Cancer, 2019 Chronic obstructive pulmonary disease (COPD) and lung cancer are global high incidence and high mortality diseases, which seriously increase the socio-economic burden. Smoke exposure, genetic susceptibility and chronic inflammation are common susceptible
Jinhua ZHOU, Wei WANG, Ruijuan LIU
doaj +1 more source
Kinetics of expression in the tissues after transfer of Treg and CCR2-Treg cells
, 2011 Copyright information:Taken from "Therapy for pneumonitis and sialadenitis by accumulation of CCR2-expressing CD4CD25regulatory T cells in MRL/lpr mice"http://arthritis-research.com/content/9/1/R15Arthritis Research & Therapy 2007;9(1):R15-R15.Published ...
Masaki Yasukawa (28387) +5 more
core +1 more source